Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rainer L Heuchel"'
Autor:
Guan-Xian Liu, You-Qi Li, Xiao R Huang, Lihua Wei, Hai-Yong Chen, Yong-Jun Shi, Rainer L Heuchel, Hui Y Lan
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53573 (2013)
Smad7 is an inhibitory Smad and plays a protective role in obstructive and diabetic kidney disease. However, the role and mechanisms of Smad7 in hypertensive nephropathy remains unexplored. Thus, the aim of this study was to investigate the role and
Externí odkaz:
https://doaj.org/article/767a84863a7144b897f0843fc5ff7a4f
Autor:
Carlos Fernández Moro, Natalie Geyer, Sara Harrizi, Yousra Hamidi, Sara Söderqvist, Danyil Kuznyecov, Evelina Tidholm Qvist, Media Salmonson Schaad, Laura Hermann, Amanda Lindberg, Rainer L. Heuchel, Alfonso Martín-Bernabé, Soniya Dhanjal, Anna C. Navis, Christina Villard, Andrea C. del Valle, Lorand Bozóky, Ernesto Sparrelid, Luc Dirix, Carina Strell, Arne Östman, Bernhard Schmierer, Peter B. Vermeulen, Jennie Engstrand, Béla Bozóky, Marco Gerling
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract A perimetastatic capsule is a strong positive prognostic factor in liver metastases, but its origin remains unclear. Here, we systematically quantify the capsule’s extent and cellular composition in 263 patients with colorectal cancer live
Externí odkaz:
https://doaj.org/article/1e0e733410a64db5b9017544b7a2ff5f
Publikováno v:
Pancreas. 50:1427-1434
Transforming growth factor-β (TGF-β)-mediated accumulation of extracellular matrix proteins such as collagen I is a common feature of fibrosis. Pancreatic stellate cells play an integral role in the pathogenesis of pancreatitis, and their profibrot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b2a3e67bf22ff2a1a00fa986a3123f7
https://doi.org/10.1097/mpa.0000000000001951
https://doi.org/10.1097/mpa.0000000000001951
Publikováno v:
Signal Transduction and Targeted Therapy. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78be495460bf45b8e2302ffce532e8d8
https://doi.org/10.1038/s41392-022-01203-8
https://doi.org/10.1038/s41392-022-01203-8
Autor:
Benedek Bozóky, Carlos Fernández Moro, Carina Strell, Natalie Geyer, Rainer L. Heuchel, J. Matthias Löhr, Ingemar Ernberg, Laszlo Szekely, Marco Gerling, Béla Bozóky
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1300-1306 (2021)
Introduction: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive solid tumors. Based on transcriptomic classifiers, basal-like and classical PDAC subtypes have been defined that differ in prognosis. Cells of both subtypes can coexi
Externí odkaz:
https://doaj.org/article/91e8e2b3c7e24a6e950edafe3ff950a1