Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Rainer Kneuer"'
Autor:
Rahel H. Wallimann, Heloïse Hensinger, Cristina Müller, Roger Schibli, Rainer Kneuer, Patrick Schindler
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 299 (2024)
In recent years, nuclear medicine has gained great interest, partly due to the success story of [177Lu]Lu-PSMA-617 (PluvictoTM). Still, in-depth preclinical characterization of radiopharmaceuticals mainly happens at centers that allow working with ra
Externí odkaz:
https://doaj.org/article/77bda5efd8434174b9780130724b3d16
Autor:
Julia Baguña Torres, Jay Roodselaar, Megan Sealey, Marina Ziehn, Marc Bigaud, Rainer Kneuer, David Leppert, Gisbert Weckbecker, Bart Cornelissen, Daniel C. Anthony
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Approval of B-cell-depleting therapies signifies an important advance in the treatment of multiple sclerosis (MS). However, it is unclear whether the administration route of anti-CD20 monoclonal antibodies (mAbs) alters tissue distribution patterns a
Externí odkaz:
https://doaj.org/article/3e65cfb68b9f41b1a866e9a64579ab0e
Autor:
Mary-Anne Migotto, Karine Mardon, Jacqueline Orian, Gisbert Weckbecker, Rainer Kneuer, Rajiv Bhalla, David C. Reutens
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Objective: To investigate the imaging and biodistribution of a novel zirconium-89 (89Zr)-labeled mouse anti-cd20 monoclonal antibody (mAb) in control and experimental autoimmune encephalomyelitis (EAE) mice following subcutaneous (s. c.) and intraven
Externí odkaz:
https://doaj.org/article/9d5c26bd5bd8411b80a70dc6efe25de7
Autor:
Diethilde Theil, Paul Smith, Catherine Huck, Yoann Gilbart, Algirdas Kakarieka, David Leppert, Celine Rauld, Cindy Schmid, Reto Baumgartner, Nathalie Stuber, Francisco Cordoba, Valerie Dubost, Katy Darribat, Magali Jivkov, Wilfried Frieauff, Rainer Kneuer, Markus Stoeckli, Stefan Reinker, Keith Mansfield, José M. Carballido, Philippe Couttet, Gisbert Weckbecker
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Ofatumumab is the first, fully human, anti-CD20 monoclonal antibody in Phase 3 development for multiple sclerosis (MS). The study focused on changes in lymphocyte subsets in blood and lymphoid tissues and on potential novel biomarkers as a result of
Externí odkaz:
https://doaj.org/article/ba3d555b05114fb2a5dab3fbd7970781
Autor:
Ian Lewis, Herbert A. Schmid, Rainer Kneuer, Daniel Hoyer, Antonio P. Silva, Gisbert Weckbecker, Christian Bruns, Janos Pless
Publikováno v:
CHIMIA, Vol 68, Iss 7-8 (2014)
A rational drug design approach involving transposition of functional groups from SRIF into a reduced size cyclohexapeptide template has led to the discovery of SOM230, a novel, stable cyclohexapeptide somatostatin mimic which exhibits unique high af
Externí odkaz:
https://doaj.org/article/acb590e64be4447a990fd182c1dd7c47
In vivo imaging with fluorescent smart probes to assess treatment strategies for acute pancreatitis.
Autor:
Abhiruchi Agarwal, Andreas Boettcher, Rainer Kneuer, Farid Sari-Sarraf, Adriana Donovan, Julian Woelcke, Oliver Simic, Trixi Brandl, Thomas Krucker
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55959 (2013)
BACKGROUND AND AIMS: Endoprotease activation is a key step in acute pancreatitis and early inhibition of these enzymes may protect from organ damage. In vivo models commonly used to evaluate protease inhibitors require animal sacrifice and therefore
Externí odkaz:
https://doaj.org/article/685a8db557fa415b8d07c6ac5aa241bb
Autor:
Abhiruchi Agarwal, Andreas Boettcher, Rainer Kneuer, Farid Sari-Sarraf, Adriana Donovan, Julian Woelcke, Oliver Simic, Trixi Brandl, Thomas Krucker
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/2cf0564e4d7e42d9aa43d1aeb843175c
Autor:
Hans-Ulrich Gremlich, Vicente Martínez, Rainer Kneuer, Willy Kinzy, Eckhard Weber, Hans-Juergen Pfannkuche, Markus Rudin
Publikováno v:
Molecular Imaging, Vol 3 (2004)
Noninvasive near-infrared fluorescence reflectance imaging (FRI) is an in vivo technique to assess physiological and molecular processes in the intact organism. Here we describe a method to assess gastric emptying in mice. TentaGel™ beads with cova
Externí odkaz:
https://doaj.org/article/9599b5637d614684b75fa9494ce21027
Autor:
Rahel H. Wallimann, Patrick Schindler, Heloïse Hensinger, Viviane J. Tschan, Sarah D. Busslinger, Rainer Kneuer, Cristina Müller, Roger Schibli
Publikováno v:
Molecular Pharmaceutics, 20 (4)
This study addresses the question whether in-ductively coupled plasma mass spectrometry (ICP-MS) can be used as a method for the in vitro and in vivo characterization of non-radioactive metal conjugates to predict the properties of analogous radiopha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b972985462646e270026444bc1106f
Autor:
Rahel Wallimann, Rainer Kneuer, Heloise Hensinger, Patrick Schindler, Anna Becker, Cristina Mueller, Roger Schibli
Publikováno v:
Nuclear Medicine and Biology. :S42-S43