Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Rainer Kalscheuer"'
Autor:
Ying Gao, Marian Frank, Nicole Teusch, Dennis Woschko, Christoph Janiak, Attila Mándi, Tibor Kurtán, Rudolf Hartmann, Katja Schiedlauske, Lasse van Geelen, Rainer Kalscheuer, Jesko Kaiser, Christoph G. W. Gertzen, Holger Gohlke, Bin-Gui Wang, Peter Proksch, Zhen Liu
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Three sulfur-containing alkaloids aplospojaveedins A–C (1–3) with a hitherto undescribed carbon skeleton comprising octahy-dronaphthalene, α, β-unsaturated lactam and glycine-cysteine moieties were isolated from Aplosporella javeedii. Their str
Externí odkaz:
https://doaj.org/article/cb0d8e5ca85a405883d413726ab9f086
Autor:
Lukas Junk, Volker M. Schmiedel, Somraj Guha, Katharina Fischel, Peter Greb, Kristin Vill, Violetta Krisilia, Lasse van Geelen, Klaus Rumpel, Parvinder Kaur, Ramya V. Krishnamurthy, Shridhar Narayanan, Radha Krishan Shandil, Mayas Singh, Christiane Kofink, Andreas Mantoulidis, Philipp Biber, Gerhard Gmaschitz, Uli Kazmaier, Anton Meinhart, Julia Leodolter, David Hoi, Sabryna Junker, Francesca Ester Morreale, Tim Clausen, Rainer Kalscheuer, Harald Weinstabl, Guido Boehmelt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Antimicrobial resistance is a global health threat that requires the development of new treatment concepts. These should not only overcome existing resistance but be designed to slow down the emergence of new resistance mechanisms. Targeted
Externí odkaz:
https://doaj.org/article/762402cfc91745d09f200167975e5d00
Publikováno v:
Molecules, Vol 29, Iss 9, p 2126 (2024)
In this study, a library of 3,7-di(hetero)aryl-substituted 10-(3-trimethylammoniumpropyl)10H-phenothiazine salts is prepared. These title compounds and their precursors are reversible redox systems with tunable potentials. The Hammett correlation giv
Externí odkaz:
https://doaj.org/article/f0bccf511c164519a6e2abc67fb96290
Autor:
Alaa Anwar, Mohamed S. Elnaggar, Ahmed M. Elissawy, Nehal Ibrahim, Attila Mándi, Tibor Kurtán, Zhen Liu, Sherweit H. El-Ahmady, Rainer Kalscheuer
Publikováno v:
Molecules, Vol 28, Iss 22, p 7650 (2023)
In this study, we report the isolation of two new meroterpenoids, miniolutelide D (1) and miniolutelide E (13-epi-miniolutelide C) (2), along with two meroterpenoidal analogues (3 and 4) and two phenolic compounds (5 and 6) from the endophytic fungus
Externí odkaz:
https://doaj.org/article/9fe91847e96247a3b87f22cfd312daec
Autor:
Mohammed Rizwan Babu Sait, Hendrik Koliwer-Brandl, Jessica A. Stewart, Benjamin M. Swarts, Marc Jacobsen, Thomas R. Ioerger, Rainer Kalscheuer
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The disaccharide trehalose is essential for viability of Mycobacterium tuberculosis, which synthesizes trehalose de novo but can also utilize exogenous trehalose. The mycobacterial cell wall encompasses two permeability barriers, the cytopla
Externí odkaz:
https://doaj.org/article/e573588583e540d78c2cd002752f7ed5
Autor:
Harwoko Harwoko, Jungho Lee, Georgios Daletos, Michael Feldbrügge, Rainer Kalscheuer, Peter Proksch
Publikováno v:
JKKI (Jurnal Kedokteran dan Kesehatan Indonesia), Pp 151-157 (2021)
Background: Genus Trichoderma of fungal kingdom are largely used as biological control agents due to broad-spectrum activity against plant pathogens. Objective: This study aimed to investigate Trichoderma harzianum, an endophytic fungus obtained from
Externí odkaz:
https://doaj.org/article/0034423bf84c4979b5ca91e2db526b87
Autor:
Xiaoli Yang, Shafaqat Ali, Manman Zhao, Lisa Richter, Vanessa Schäfer, Julian Schliehe-Diecks, Marian Frank, Jing Qi, Pia-Katharina Larsen, Jennifer Skerra, Heba Islam, Thorsten Wachtmeister, Christina Alter, Anfei Huang, Sanil Bhatia, Karl Köhrer, Carsten Kirschning, Heike Weighardt, Ulrich Kalinke, Rainer Kalscheuer, Markus Uhrberg, Stefanie Scheu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Beauvericin (BEA), a mycotoxin of the enniatin family produced by various toxigenic fungi, has been attributed multiple biological activities such as anti-cancer, anti-inflammatory, and anti-microbial functions. However, effects of BEA on dendritic c
Externí odkaz:
https://doaj.org/article/e7db736d19e84cc1b3620305b013c974
Autor:
Peter M. EZE, Ying GAO, Yang LIU, Lasse van GEELEN, Chika P. EJIKEUGWU, Charles O. ESIMONE, Festus B. C. OKOYE, Peter PROKSCH, Rainer KALSCHEUER
Publikováno v:
Notulae Scientia Biologicae, Vol 13, Iss 3 (2021)
Extremophilic fungi have received considerable attention recently as new promising sources of biologically active compounds with potential pharmaceutical applications. This study investigated the secondary metabolites of a marine-derived Penicillium
Externí odkaz:
https://doaj.org/article/3870ce33cb744ddf82ded5b11e557ecd
Autor:
Flaminia Mazzone, Viktor E. Simons, Lasse van Geelen, Marian Frank, Attila Mándi, Tibor Kurtán, Klaus Pfeffer, Rainer Kalscheuer
Publikováno v:
Antibiotics, Vol 11, Iss 9, p 1176 (2022)
Toxoplasma gondii is an apicomplexan pathogen able to infect a wide range of warm-blooded animals, including humans, leading to toxoplasmosis. Current treatments for toxoplasmosis are associated with severe side-effects and a lack efficacy to eradica
Externí odkaz:
https://doaj.org/article/6335312bf6ea440c8c7d414b4917f594
Autor:
Alexander Berger, Talea Knak, Anna-Lene Kiffe-Delf, Korana Mudrovcic, Vinayak Singh, Mathew Njoroge, Bjoern B. Burckhardt, Mohanraj Gopalswamy, Beate Lungerich, Lutz Ackermann, Holger Gohlke, Kelly Chibale, Rainer Kalscheuer, Thomas Kurz
Publikováno v:
Pharmaceuticals, Vol 15, Iss 8, p 984 (2022)
The continuous, worldwide spread of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) endanger the World Health Organization’s (WHO) goal to end the global TB pandemic by the year 2035. During the past 50 years, very
Externí odkaz:
https://doaj.org/article/f926422d1ba64ca7b14ee4203abd9260