Zobrazeno 1 - 10
of 3 046
pro vyhledávání: '"Rainer K"'
Autor:
Jannatun Nawer, Brian Stanford, Matthias Kolbe, Stephan Schneider, Stéphane Gossé, Rainer K. Wunderlich, Markus Mohr, Aurelio Borzì, Antonia Neels, Douglas M. Matson
Publikováno v:
npj Microgravity, Vol 10, Iss 1, Pp 1-6 (2024)
Abstract Evaporation control is a critical facility resource during solidification experiments that limits processing time and must be tracked to ensure facility health. A thermodynamic analysis was performed on a ternary FeCrNi sample processed onbo
Externí odkaz:
https://doaj.org/article/44f66b8e2f944dd5a338194bc1e65d1b
Autor:
Marie-Kristin Raulf, Katharina Raue, Nadja Rohdich, Eva Zschiesche, Jonathan Raue, Kristina Merhof, Holger A. Volk, Manuela Schnyder, Simone Morelli, Donato Traversa, Rainer K. A. Roepke, Christina Strube
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-15 (2024)
Abstract Background Aelurostrongylus abstrusus is one of the most important respiratory nematodes of felines. Infections may lead to respiratory clinical signs with varying severity or even death, emphasizing the need for preventive treatment of cats
Externí odkaz:
https://doaj.org/article/372d24c04abe4fb881e1aec83e274963
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract We describe nonmetal adducts of the phosphorus center of terminal phosphinidene complexes using classical C- and N-ligands from metal coordination chemistry. The nature of the L-P bond has been analyzed by various theoretical methods includi
Externí odkaz:
https://doaj.org/article/3b2fd2e04f584d86b71f8d95875defba
Autor:
Johanna Kaufmann, Nina Kathleen Blum, Falko Nagel, Anna Schuler, Julia Drube, Carsten Degenhart, Julian Engel, Jan Eicke Eickhoff, Pooja Dasgupta, Sebastian Fritzwanker, Maria Guastadisegni, Clemens Schulte, Elke Miess-Tanneberg, Hans Michael Maric, Mariana Spetea, Andrea Kliewer, Matthias Baumann, Bert Klebl, Rainer K. Reinscheid, Carsten Hoffmann, Stefan Schulz
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
A G protein-coupled receptors (GPCRs) phosphorylation assay for cell culture plates can be used for ligand profiling and inhibitor screening, as evidenced by the identification of two GRK inhibitor compounds.
Externí odkaz:
https://doaj.org/article/6d354c7b140b4e0489510cad7b49570b
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
BackgroundHealthy brain development depends on early social practices and experiences. The risk gene CACNA1C is implicated in numerous neuropsychiatric disorders, in which key characteristics include deficits in social functioning and communication.
Externí odkaz:
https://doaj.org/article/96b96acaaf6e43cd8c0c5f612a8553c6
Autor:
Pooja Dasgupta, Anika Mann, Willma E. Polgar, Rainer K. Reinscheid, Nurulain T. Zaveri, Stefan Schulz
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Multi-receptor targeting has been proposed as a promising strategy for the development of opioid analgesics with fewer side effects. Cebranopadol and AT-121 are prototypical bifunctional ligands targeting the nociceptin/orphanin FQ peptide r
Externí odkaz:
https://doaj.org/article/d9bd7e74763c49baa260dbab828e0fd3
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Ionizing radiations encountered by astronauts on deep space missions produce biological damage by two main mechanisms: (1) Targeted effects (TE) due to direct traversals of cells by ionizing tracks. (2) Non-targeted effects (NTE) caused by r
Externí odkaz:
https://doaj.org/article/33e3e998520d412cbba849112b6b1ca1
Autor:
Sebastian Fritzwanker, Lionel Moulédous, Catherine Mollereau, Carine Froment, Odile Burlet-Schiltz, Felix Effah, Alexis Bailey, Mariana Spetea, Rainer K. Reinscheid, Stefan Schulz, Andrea Kliewer
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Fritzwanker et al. develop a knock-in transgenic mouse line in which the hemagglutinin epitope tag sequence is fused with the amino-terminus of the µ-opioid receptor. Their model enables more efficient immunodetection of G protein-coupled receptors.
Externí odkaz:
https://doaj.org/article/495c33f2d6324ceca45d00dab8a2f7bb
Autor:
Hauke Fender, Kim Walter, Aytug K. Kiper, Jelena Plačkić, Theresa M. Kisko, Moria D. Braun, Rainer K. W. Schwarting, Susanne Rohrbach, Markus Wöhr, Niels Decher, Jens Kockskämper
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 9795 (2023)
CACNA1C encodes the pore-forming α1C subunit of the L-type Ca2+ channel, Cav1.2. Mutations and polymorphisms of the gene are associated with neuropsychiatric and cardiac disease. Haploinsufficient Cacna1c+/− rats represent a recently developed mod
Externí odkaz:
https://doaj.org/article/d9f78659843d41f8b4d58c8056c80183
Autor:
Katharina Raue, Nadja Rohdich, Daniela Hauck, Eva Zschiesche, Simone Morelli, Donato Traversa, Angela Di Cesare, Rainer K. A. Roepke, Christina Strube
Publikováno v:
Parasites & Vectors, Vol 14, Iss 1, Pp 1-10 (2021)
Abstract Background The feline lungworm Aelurostrongylus abstrusus affects the lower respiratory tract in cats worldwide. As infections may lead to chronic respiratory changes or even death, preventive treatment in cats with outdoor access is warrant
Externí odkaz:
https://doaj.org/article/5689104aa1d641dfbffc5e67791ab656