Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Rainer Haeckel"'
Autor:
Rainer Haeckel, Tatjana Ammer, Werner Wosniok, Alexander Krebs, Antje Torge, Mustafa Özcürümez, Alexander Bertram
Publikováno v:
Journal of Laboratory Medicine. 47:55-62
Objectives Reference intervals of total cholesterol concentrations in plasma and of their fractions low-density lipoprotein (LDL)-, high-density lipoprotein (HDL)-and non-HDL concentrations are seldom studied with respect to the relevance of age and
Publikováno v:
Clinica Chimica Acta. 523:437-440
The concept of reference change values (RCVs) for diagnosis and monitoring of diseases has become well established. Several models habe been developed, e. g. one assuming a normal distribution and another one for a log-normal distribution. RCV values
Publikováno v:
Clinical chemistry and laboratory medicineReferences.
Reference intervals are established either by direct or indirect approaches. Whereas the definition of direct is well established, the definition of indirect is still a matter of debate. In this paper, a general definition that covers all indirect mo
Autor:
Rainer Haeckel, Werner Wosniok
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM). 59:1628-1633
Objectives There are generally two major reasons for the comparison of reference intervals (RIs): when externally determined RIs (from the literature or provided by a manufacturer) are compared with presently used intra-laboratory RIs and when indire
Publikováno v:
Journal of Laboratory Medicine, Vol 45, Iss 2, Pp 87-94 (2021)
A new model for the indirect estimation of reference limits (RLs) has been proposed recently and was coined TMC approach (truncated minimum chi-square estimation) which can be performed with R statistic. A spline function is applied to the RLs to get
Autor:
Thomas Streichert, Anja Figge, Antje Torge, Rainer Haeckel, Farhad Arzideh, Mustafa Özcürümez
Publikováno v:
Journal of Laboratory Medicine, Vol 45, Iss 2, Pp 111-119 (2021)
Objectives Plasma glucose concentrations exhibit a pronounced daytime-dependent variation. The oscillations responsible for this are currently not considered in the determination of reference limits (RL) and decision limits. Methods We characterized
Publikováno v:
Journal of Laboratory Medicine, Vol 45, Iss 2, Pp 103-109 (2021)
Objectives Indirect methods for the estimation of Reference Limits (RLs) use large data pools stored in modern laboratory information’s systems. To avoid correlation between observations repeated results from each patient should be excluded. Some d
Publikováno v:
Journal of Laboratory Medicine, Vol 45, Iss 2, Pp 35-53 (2021)
Reference intervals (RIs) can be determined by direct and indirect procedures. Both approaches identify a reference population from which the RIs are defined. The crucial difference between direct and indirect methods is that direct methods select pa
Publikováno v:
Journal of Laboratory Medicine, Vol 45, Iss 2, Pp 121-124 (2021)
It has been observed that the estimation of reference intervals of leukocytes in whole venous blood leads to higher upper reference limits (uRLs) with indirect methods than has been reported in the literature determined by direct approaches. This phe
Autor:
Rainer Haeckel, Ralf Junker, Antje Torge, Matthias Orth, Alexander Bertram, Alexander Krebs, Mustafa Özcürümez, Werner Wosniok, Thomas Streichert
Publikováno v:
Journal of Laboratory Medicine. 45:95-101
The glucose concentration in plasma or serum is one of the most often requested analytical values in laboratory medicine. Whereas the analytical part of the glucose determination is well standardised, the standardisation of the pre-examination part (