Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Rainer Albert"'
Autor:
Ian Lewis, Gisbert Weckbecker, Herbert A. Schmid, Steven W.J. Lamberts, Viktor Boerlin, Joost van der Hoek, Günter Bovermann, Lukas Oberer, Janos Pless, Nagarajan Chandramouli, Wilfried Bauer, Rainer Albert, Christian Bruns
Publikováno v:
CHIMIA, Vol 58, Iss 4 (2004)
A rational drug design approach involving transposition of functional groups from SRIF into a reduced size cyclohexapeptide template has led to the discovery of SOM230, a novel, stable cyclohexapeptide somatostatin mimic which exhibits unique high af
Externí odkaz:
https://doaj.org/article/d902474928ed4ac9b119a949dab0d176
Autor:
Meyer, Sascha Rainer Albert1,2 (AUTHOR), Boelaarts, Leo1 (AUTHOR), Lindeboom, Jaap3 (AUTHOR), De Jonghe, Jos F. M.1 (AUTHOR), Ponds, Rudolf4 (AUTHOR)
Publikováno v:
Applied Neuropsychology: Adult. Jan/Feb 2022, Vol. 29 Issue 1, p23-31. 9p. 2 Charts, 1 Graph.
Autor:
Kortunov, Pavel, Chmelik, Christian, Kärger, Jörg, Rakoczy, Rainer Albert, Ruthven, Douglas M., Traa, Yvonne, Vasenkov, Sergey, Weitkamp, Jens, Ito, Taro
Publikováno v:
Diffusion fundamentals. 2(96):1-2
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A14433
https://ul.qucosa.de/api/qucosa%3A14433/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A14433/attachment/ATT-0/
Akademický článek
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Autor:
Eric Francotte, Danilo Guerini, Markus Streiff, Markus Zollinger, Karl Welzenbach, Rainer Albert, Klaus Hinterding, Trixie Wagner, Helmut Knecht, Nigel Graham Cooke, Frédéric Zecri, Corinne Simeon, Constanze Müller-Hartwieg, Volker Brinkmann
Publikováno v:
Journal of Medicinal Chemistry. 48:5373-5377
In vivo phosphorylation of FTY720 (1) in rats and humans resulted exclusively in the biologically active (S)-configured enantiomer, which was proven by an ex vivo o-phthaldialdehyde derivatization protocol especially elaborated for phosphates of 1. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b15be152523830d14deb51d14f71330
https://doi.org/10.1021/jm050242f
https://doi.org/10.1021/jm050242f
Autor:
Sompong, Wattanasin, Joerg, Kallen, Stewart, Myers, Qin, Guo, Michael, Sabio, Claus, Ehrhardt, Rainer, Albert, Ulrich, Hommel, Gisbert, Weckbecker, Karl, Welzenbach, Gabriele, Weitz-Schmidt
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:1217-1220
1,4-Diazepane-2,5-diones (2) are found to be a new class of potent LFA-1 inhibitors. The synthesis, structure, and biological evaluation of these 1,4-diazepine-2,5-diones and related derivatives are described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f65d17c722f1e9f1c1e00fc6d2f5bf
https://doi.org/10.1016/j.bmcl.2004.11.072
https://doi.org/10.1016/j.bmcl.2004.11.072
Autor:
Rainer Albert, Herbert A. Schmid, Gisbert Weckbecker, Daniel Hoyer, Christian Bruns, Ian Lewis
Publikováno v:
Scopus-Elsevier
Somatostatins — also known as somatotropin-release inhibiting factors (SRIFs) — are a family of cyclopeptides that have broad inhibitory effects on the secretion of hormones such as growth hormone, insulin and glucagon. These effects have formed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2195896e24cc0dd54e86da696e2e9241
https://doi.org/10.1038/nrd1255
https://doi.org/10.1038/nrd1255
Autor:
Klemens Hoegenauer, Sylvain Cottens, Peter Nussbaumer, Frédéric Zecri, Peter Buehlmayer, Nathanael S. Gray, Shifeng Pan, Rainer Albert, Klaus Hinterding, Carsten Spanka, Peter Ettmayer, Volker Brinkmann
Publikováno v:
Synthesis. 2003:1667-1670
Efficient and versatile protocols for the synthesis of chiral analogues of the novel immunomodulator FTY720 and its phosphate are described. These synthetic procedures allow for broad structural variation and deliver essential tools to further elucid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6ea5217d1245081996932ac4d345f6e
https://doi.org/10.1055/s-2003-40883
https://doi.org/10.1055/s-2003-40883
Autor:
Ian Lewis, Wilfried Bauer, Gisbert Weckbecker, Rainer Albert, Nagarajan Chandramouli, Janos Pless, Christian Bruns
Publikováno v:
Journal of Medicinal Chemistry. 46:2334-2344
A rational drug design approach, capitalizing on structure-activity relationships and involving transposition of functional groups from somatotropin release inhibitory factor (SRIF) into a reduced size cyclohexapeptide template, has led to the discov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782039056c4de32378516f03d8b81df7
https://doi.org/10.1021/jm021093t
https://doi.org/10.1021/jm021093t
Autor:
Hans Peter Weber, Valerie Hungerford, Elsebeth Andersen, Francis Bitch, Christos Papageorgiou, Max H. Schreier, Rainer Albert, Michel Lemaire, Philipp Floersheim
Publikováno v:
Journal of Medicinal Chemistry. 41:3530-3538
T-cell immunosuppressant-based therapies efficiently control early graft rejection in allotransplantation settings. They fail, however, to prevent those rejection events which are mediated by transplant-induced antibody (Ab) responses such as those i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::728db18c87b4d4635657878ba4cff0e0
https://doi.org/10.1021/jm981028c
https://doi.org/10.1021/jm981028c