Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rainer, Winstel"'
Publikováno v:
Drugs in R&D. 17:305-312
Ovaleap® (XM17) is a recombinant human follicle-stimulating hormone to treat infertility by inducing ovulation or controlled ovarian stimulation for assisted reproductive technology (ART) procedures. Ovaleap® (follitropin-α) was approved by the Eu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384025a56de349ad8816de812a7d9b5c
https://doi.org/10.1007/s40268-017-0182-z
https://doi.org/10.1007/s40268-017-0182-z
Publikováno v:
Drugs in R&D
Ovaleap® (XM17) is a recombinant human follicle-stimulating hormone to treat infertility by inducing ovulation or controlled ovarian stimulation for assisted reproductive technology (ART) procedures. Ovaleap® (follitropin-α) was approved by the Eu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cfe8e049cec5681c6f8815173045d868
https://pubmed.ncbi.nlm.nih.gov/28386738
https://pubmed.ncbi.nlm.nih.gov/28386738
Publikováno v:
Kidney International. 49:1047-1052
G-protein-coupled receptor kinases. β-Adrenergic receptors are prototypes of the many G-protein-coupled receptors. Activation and inactivation of these receptors are regulated by multiple mechanisms which can affect either their function or their ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc7c907d8ed699d013235dda1d590ff
https://doi.org/10.1038/ki.1996.153
https://doi.org/10.1038/ki.1996.153
Publikováno v:
Biochemical pharmacology. 70(7)
G protein-coupled receptor kinases (GRKs) are regulatory enzymes involved in the modulation of seven-transmembrane-helix receptors. In order to develop specific inhibitors for these kinases, we synthesized and investigated peptide inhibitors derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c72aa63f849057834cb85d18267a720
https://pubmed.ncbi.nlm.nih.gov/16102734
https://pubmed.ncbi.nlm.nih.gov/16102734
Autor:
Martin J. Lohse, Cornelius Krasel, Rainer Winstel, Harald Mischak, Jörg Brockmann, Sascha Dammeier
Publikováno v:
The Journal of biological chemistry. 276(3)
G-protein-coupled receptor kinases (GRKs) are important regulators of G-protein-coupled receptor function. Two members of this family L, GRK2 and GRK5 L, have been shown to be substrates for protein kinase C (PKC). Whereas PKC-mediated phosphorylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6123f738099abcb1adfd3a77218c45
https://pubmed.ncbi.nlm.nih.gov/11042191
https://pubmed.ncbi.nlm.nih.gov/11042191
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 96(10)
Homologous desensitization of G protein-coupled receptors is thought to occur in several steps: binding of G protein-coupled receptor kinases (GRKs) to receptors, receptor phosphorylation, kinase dissociation, and finally binding of β-arrestins to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711182538520414564dc7baf9d9fc512
https://pubmed.ncbi.nlm.nih.gov/10318908
https://pubmed.ncbi.nlm.nih.gov/10318908
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 93(5)
The beta-adrenergic receptor kinase (betaARK) is the prototypical member of the family of cytosolic kinases that phosphorylate guanine nucleotide binding-protein-coupled receptors and thereby trigger uncoupling between receptors and guanine nucleotid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea01f8f0957c93ab641d424afb589b0
https://pubmed.ncbi.nlm.nih.gov/8700892
https://pubmed.ncbi.nlm.nih.gov/8700892