Zobrazeno 1 - 10
of 599
pro vyhledávání: '"Rainer, Schulz"'
Autor:
Rolf Schreckenberg, Rainer Schulz, Nadja Itani, Peter Ferdinandy, Peter Bencsik, Tamara Szabados, Susanne Rohrbach, Bernd Niemann, Klaus-Dieter Schlüter
Publikováno v:
Redox Biology, Vol 76, Iss , Pp 103308- (2024)
In rats decreased bioavailability of nitric oxide induces oxidative stress and right heart failure. Oxidative stress can activate matrix metalloproteinase-2 (MMP2). We addressed the question whether increasing oxidative defense by administration of t
Externí odkaz:
https://doaj.org/article/319c7419566c47558947845e0c22dd7b
Autor:
Mette Sørensen, Göran Pershagen, Jesse Daniel Thacher, Timo Lanki, Benedikt Wicki, Martin Röösli, Danielle Vienneau, Manuella Lech Cantuaria, Jesper Hvass Schmidt, Gunn Marit Aasvang, Sadeer Al-Kindi, Michael T. Osborne, Philip Wenzel, Juan Sastre, Ingrid Fleming, Rainer Schulz, Omar Hahad, Marin Kuntic, Jacek Zielonka, Helmut Sies, Tilman Grune, Katie Frenis, Thomas Münzel, Andreas Daiber
Publikováno v:
Redox Biology, Vol 69, Iss , Pp 102995- (2024)
Transportation noise is a ubiquitous urban exposure. In 2018, the World Health Organization concluded that chronic exposure to road traffic noise is a risk factor for ischemic heart disease. In contrast, they concluded that the quality of evidence fo
Externí odkaz:
https://doaj.org/article/9422ae74b23f4599bfc0b65004a7dfa1
Autor:
Paulin Brosinsky, Jacqueline Heger, Akylbek Sydykov, Astrid Weiss, Stephan Klatt, Laureen Czech, Simone Kraut, Ralph Theo Schermuly, Klaus-Dieter Schlüter, Rainer Schulz
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6212 (2024)
Increased mitochondrial reactive oxygen species (ROS) formation is important for the development of right ventricular (RV) hypertrophy (RVH) and failure (RVF) during pulmonary hypertension (PH). ROS molecules are produced in different compartments wi
Externí odkaz:
https://doaj.org/article/d7e972d26d56448bb81b561a9a215258
Autor:
Gerd Heusch, Ioanna Andreadou, Robert Bell, Edoardo Bertero, Hans-Erik Botker, Sean M. Davidson, James Downey, Philip Eaton, Peter Ferdinandy, Bernard J. Gersh, Mauro Giacca, Derek J. Hausenloy, Borja Ibanez, Thomas Krieg, Christoph Maack, Rainer Schulz, Frank Sellke, Ajay M. Shah, Holger Thiele, Derek M. Yellon, Fabio Di Lisa
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102894- (2023)
The present review summarizes the beneficial and detrimental roles of reactive oxygen species in myocardial ischemia/reperfusion injury and cardioprotection. In the first part, the continued need for cardioprotection beyond that by rapid reperfusion
Externí odkaz:
https://doaj.org/article/0fa5d92cdebd454588eef18a999eac76
Autor:
Jacqueline Heger, Stefan Partsch, Claudia Harjung, Zoltán V. Varga, Tamás Baranyai, Johannes Weiß, Lea Kremer, Fabian Locquet, Przemyslaw Leszek, Bence Ágg, Bettina Benczik, Péter Ferdinandy, Rainer Schulz, Gerhild Euler
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 401 (2023)
Cardiac hypertrophy resulting from sympathetic nervous system activation triggers the development of heart failure. The transcription factor Y-box binding protein 1 (YB-1) can interact with transcription factors involved in cardiac hypertrophy and ma
Externí odkaz:
https://doaj.org/article/43a811068dde42149ee976eccc024c5a
Autor:
Kathleen Pappritz, Jie Lin, Muhammad El‐Shafeey, Henry Fechner, Uwe Kühl, Alessio Alogna, Frank Spillmann, Ahmed Elsanhoury, Rainer Schulz, Carsten Tschöpe, Sophie Van Linthout
Publikováno v:
ESC Heart Failure, Vol 9, Iss 2, Pp 925-941 (2022)
Abstract Aim The acute phase of a coxsackievirus 3 (CVB3)‐induced myocarditis involves direct toxic cardiac effects and the systemic activation of the immune system, including the cardiosplenic axis. Consequently, the nucleotide‐binding oligomeri
Externí odkaz:
https://doaj.org/article/a2758d127c774136b0ea4616cf588917
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Connexins are known for their ability to mediate cell-cell communication via gap junctions and also form hemichannels that pass ions and molecules over the plasma membrane when open. Connexins have also been detected within mitochondria, with mitocho
Externí odkaz:
https://doaj.org/article/2a89740f74f345cfac609b10d460888f
Autor:
Jonas Knittel, Nadja Itani, Rolf Schreckenberg, Jacqueline Heger, Susanne Rohrbach, Rainer Schulz, Klaus-Dieter Schlüter
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 1013 (2023)
Serotonin effects on cardiac hypertrophy, senescence, and failure are dependent either on activation of specific receptors or serotonin uptake and serotonin degradation by monoamine oxidases (MAOs). Receptor-dependent effects are specific for seroton
Externí odkaz:
https://doaj.org/article/f240e7988aa94e02894008905ab7a2ea
Autor:
Jacqueline Heger, Tamara Szabados, Paulin Brosinsky, Péter Bencsik, Péter Ferdinandy, Rainer Schulz
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6443 (2023)
The cardiomyocyte-specific knockout (KO) of monoamine oxidase (MAO)-B, an enzyme involved in the formation of reactive oxygen species (ROS), reduced myocardial ischemia/reperfusion (I/R) injury in vitro. Because sex hormones have a strong impact on M
Externí odkaz:
https://doaj.org/article/4f7e93355ab24b3b92a934af76214f17
Autor:
Rainer Schulz, Klaus-Dieter Schlüter
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6459 (2023)
On the one hand, reactive oxygen species (ROS) are involved in the onset and progression of a wide array of diseases. On the other hand, these are a part of signaling pathways related to cell metabolism, growth and survival. While ROS are produced at
Externí odkaz:
https://doaj.org/article/072de334d6d34158941febf1660a04df