Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Rainer, Koenig"'
Autor:
Eunice O Adedeji, Thomas Beder, Claudia Damiani, Alessia Cappelli, Anastasia Accoti, Sofia Tapanelli, Olubanke O Ogunlana, Segun Fatumo, Guido Favia, Rainer Koenig, Ezekiel Adebiyi
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0305207 (2024)
Increasing reports of insecticide resistance continue to hamper the gains of vector control strategies in curbing malaria transmission. This makes identifying new insecticide targets or alternative vector control strategies necessary. CLassifier of E
Externí odkaz:
https://doaj.org/article/dc19d1869641424faacd2db7e04c0150
Autor:
Maximilian A. Kelch, Antonella Vera-Guapi, Thomas Beder, Marcus Oswald, Alicia Hiemisch, Nina Beil, Piotr Wajda, Sandra Ciesek, Holger Erfle, Tuna Toptan, Rainer Koenig
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Expanding antiviral treatment options against SARS-CoV-2 remains crucial as the virus evolves under selection pressure which already led to the emergence of several drug resistant strains. Broad spectrum host-directed antivirals (HDA) are promising t
Externí odkaz:
https://doaj.org/article/05c0f34c61634c5bbd7d2b6ac3cac832
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-23 (2022)
Abstract Background Elucidating cellular metabolism led to many breakthroughs in biotechnology, synthetic biology, and health sciences. To date, deriving metabolic fluxes by 13C tracer experiments is the most prominent approach for studying metabolic
Externí odkaz:
https://doaj.org/article/15fce799bc2a45ecbbc5b262b5ea936f
Autor:
Olufemi Tony Aromolaran, Itunu Isewon, Eunice Adedeji, Marcus Oswald, Ezekiel Adebiyi, Rainer Koenig, Jelili Oyelade
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0288023 (2023)
Computational prediction of absolute essential genes using machine learning has gained wide attention in recent years. However, essential genes are mostly conditional and not absolute. Experimental techniques provide a reliable approach of identifyin
Externí odkaz:
https://doaj.org/article/3309f46a0c954a7aae2284c17b6f72b9
Autor:
Olufemi Aromolaran, Thomas Beder, Eunice Adedeji, Yvonne Ajamma, Jelili Oyelade, Ezekiel Adebiyi, Rainer Koenig
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 4581-4592 (2021)
Pathogens causing infections, and particularly when invading the host cells, require the host cell machinery for efficient regeneration and proliferation during infection. For their life cycle, host proteins are needed and these Host Dependency Facto
Externí odkaz:
https://doaj.org/article/864a4b40c5c9449dacb121860a0d2548
Autor:
Eunice Oluwatobiloba Adedeji, Olubanke Olujoke Ogunlana, Segun Fatumo, Thomas Beder, Yvonne Ajamma, Rainer Koenig, Ezekiel Adebiyi
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-30 (2020)
Abstract The increasing resistance to currently available insecticides in the malaria vector, Anopheles mosquitoes, hampers their use as an effective vector control strategy for the prevention of malaria transmission. Therefore, there is need for new
Externí odkaz:
https://doaj.org/article/ad2bf0d1ed3a4bab963d89c509518483
Autor:
Olufemi Aromolaran, Thomas Beder, Marcus Oswald, Jelili Oyelade, Ezekiel Adebiyi, Rainer Koenig
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 612-621 (2020)
Genes are termed to be essential if their loss of function compromises viability or results in profound loss of fitness. On the genome scale, these genes can be determined experimentally employing RNAi or knockout screens, but this is very resource i
Externí odkaz:
https://doaj.org/article/8fa7838d7b674acbb659111fae35f764
Autor:
Eunice O. Adedeji, Gbolahan O. Oduselu, Olubanke O. Ogunlana, Segun Fatumo, Rainer Koenig, Ezekiel Adebiyi
Publikováno v:
Insects, Vol 13, Iss 11, p 1070 (2022)
Trehalase inhibitors are considered safe alternatives for insecticides and fungicides. However, there are no studies testing these compounds on Anopheles gambiae, a major vector of human malaria. This study predicted the three-dimensional structure o
Externí odkaz:
https://doaj.org/article/7f34687ced9542ea9cc65110685433e3
Publikováno v:
American Journal of Medical Genetics Part A. 188:2969-2975
Autor:
Joe Rainger, Ellen van Beusekom, Jacqueline K Ramsay, Lisa McKie, Lihadh Al-Gazali, Rosanna Pallotta, Anita Saponari, Peter Branney, Malcolm Fisher, Harris Morrison, Louise Bicknell, Philippe Gautier, Paul Perry, Kishan Sokhi, David Sexton, Tanya M Bardakjian, Adele S Schneider, Nursel Elcioglu, Ferda Ozkinay, Rainer Koenig, Andre Mégarbané, C Nur Semerci, Ayesha Khan, Saemah Zafar, Raoul Hennekam, Sérgio B Sousa, Lina Ramos, Livia Garavelli, Andrea Superti Furga, Anita Wischmeijer, Ian J Jackson, Gabriele Gillessen-Kaesbach, Han G Brunner, Dagmar Wieczorek, Hans van Bokhoven, David R FitzPatrick
Publikováno v:
PLoS Genetics, Vol 14, Iss 12, p e1007866 (2018)
[This corrects the article DOI: 10.1371/journal.pgen.1002114.].
Externí odkaz:
https://doaj.org/article/5eacb5aa2aef4ceabdeb674476983ece