Zobrazeno 1 - 10
of 505
pro vyhledávání: '"Rainer, Blasczyk"'
Autor:
Zhiwei Liu, Yang Luo, Samuel Kirimunda, Murielle Verboom, Olusegun O. Onabajo, Mateus H. Gouveia, Martin D. Ogwang, Patrick Kerchan, Steven J. Reynolds, Constance N. Tenge, Pamela A. Were, Robert T. Kuremu, Walter N. Wekesa, Nestory Masalu, Esther Kawira, Tobias Kinyera, Isaac Otim, Ismail D. Legason, Hadijah Nabalende, Herry Dhudha, Leona W. Ayers, Kishor Bhatia, James J. Goedert, Nathan Cole, Wen Luo, Jia Liu, Michelle Manning, Belynda Hicks, Ludmila Prokunina-Olsson, George Chagaluka, W. Thomas Johnston, Nora Mutalima, Eric Borgstein, George N. Liomba, Steve Kamiza, Nyengo Mkandawire, Collins Mitambo, Elizabeth M. Molyneux, Robert Newton, Ann W. Hsing, James E. Mensah, Anthony A. Adjei, Amy Hutchinson, Mary Carrington, Meredith Yeager, Rainer Blasczyk, Stephen J. Chanock, Soumya Raychaudhuri, Sam M. Mbulaiteye
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract Burkitt lymphoma (BL) is responsible for many childhood cancers in sub-Saharan Africa, where it is linked to recurrent or chronic infection by Epstein-Barr virus or Plasmodium falciparum. However, whether human leukocyte antigen (HLA) polymo
Externí odkaz:
https://doaj.org/article/9dbb6d4ddc894347a08013feb54d1c14
Autor:
Katharina Schmalkuche, Tamina Rother, Jonathan M. Burgmann, Henrike Voß, Klaus Höffler, Günes Dogan, Arjang Ruhparwar, Jan D. Schmitto, Rainer Blasczyk, Constanca Figueiredo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Heart transplantation is associated with major hurdles, including the limited number of available organs for transplantation, the risk of rejection due to genetic discrepancies, and the burden of immunosuppression. In this study, we demonstrated the
Externí odkaz:
https://doaj.org/article/7159c2abd33b4a21b8e9532868962379
Autor:
Markus Benedikt Krueger, Agnes Bonifacius, Anna Christina Dragon, Maria Michela Santamorena, Björn Nashan, Richard Taubert, Ulrich Kalinke, Britta Maecker-Kolhoff, Rainer Blasczyk, Britta Eiz-Vesper
Publikováno v:
Transplant International, Vol 37 (2024)
Infectious complications, including widespread human cytomegalovirus (CMV) disease, frequently occur after hematopoietic stem cell and solid organ transplantation due to immunosuppressive treatment causing impairment of T-cell immunity. Therefore, in
Externí odkaz:
https://doaj.org/article/2510528d4a8b4271b8afed71ba6d2b25
Autor:
Katharina Schmalkuche, Tamina Rother, Sevval Besli, Reinhard Schwinzer, Rainer Blasczyk, Björn Petersen, Constanca Figueiredo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Xenotransplantation offers a promising alternative to circumvent the lack of donated human organs available for transplantation. Different attempts to improve the survival of xenografts led to the generation of transgenic pigs expressing various comb
Externí odkaz:
https://doaj.org/article/9127359b36e848a995a3a66ff4a47181
Autor:
Anna Christina Dragon, Luca Marie Beermann, Melina Umland, Agnes Bonifacius, Chiara Malinconico, Louisa Ruhl, Patrik Kehler, Johanna Gellert, Lisa Weiß, Sarah Mayer-Hain, Katharina Zimmermann, Sebastian Riese, Felicitas Thol, Gernot Beutel, Britta Maecker-Kolhoff, Fumiichiro Yamamoto, Rainer Blasczyk, Axel Schambach, Michael Hust, Michael Hudecek, Britta Eiz-Vesper
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionChimeric antigen receptor-engineered T cells (CAR-Ts) are investigated in various clinical trials for the treatment of cancer entities beyond hematologic malignancies. A major hurdle is the identification of a target antigen with high exp
Externí odkaz:
https://doaj.org/article/46ba9e9337d34affb73dc677378f3afa
Autor:
Agnes Bonifacius, Britta Lamottke, Sabine Tischer-Zimmermann, Rebecca Schultze-Florey, Lilia Goudeva, Hans-Gert Heuft, Lubomir Arseniev, Rita Beier, Gernot Beutel, Gunnar Cario, Birgit Fröhlich, Johann Greil, Leo Hansmann, Justin Hasenkamp, Michaela Höfs, Patrick Hundsdoerfer, Edgar Jost, Kinan Kafa, Oliver Kriege, Nicolaus Kröger, Stephan Mathas, Roland Meisel, Michaela Nathrath, Mervi Putkonen, Sarina Ravens, Hans Christian Reinhardt, Elisa Sala, Martin G. Sauer, Clemens Schmitt, Roland Schroers, Nina Kristin Steckel, Ralf Ulrich Trappe, Mareike Verbeek, Daniel Wolff, Rainer Blasczyk, Britta Eiz-Vesper, Britta Maecker-Kolhoff
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
BACKGROUND Adoptive transfer of EBV-specific T cells can restore specific immunity in immunocompromised patients with EBV-associated complications.METHODS We provide results of a personalized T cell manufacturing program evaluating donor, patient, T
Externí odkaz:
https://doaj.org/article/90b7781e7f1547e9ab2df6d697ea2d7d
Autor:
Tamina Rother, Carina Horgby, Katharina Schmalkuche, Jonathan M. Burgmann, Fabian Nocke, Johannes Jägers, Jessica Schmitz, Jan Hinrich Bräsen, Miriam Cantore, Franck Zal, Katja B. Ferenz, Rainer Blasczyk, Constanca Figueiredo
Publikováno v:
Frontiers in Transplantation, Vol 2 (2023)
Normothermic ex-vivo machine perfusion provides a powerful tool to improve donor kidney preservation and a route for the delivery of pharmacological or gene therapeutic interventions prior to transplantation. However, perfusion at normothermic temper
Externí odkaz:
https://doaj.org/article/dab9afa8e791448ea00dfb4b56dff5ce
Autor:
Sabine Tischer-Zimmermann, Elisabeth Salzer, Tamires Bitencourt, Nelli Frank, Christine Hoffmann-Freimüller, Julia Stemberger, Britta Maecker-Kolhoff, Rainer Blasczyk, Volker Witt, Gerhard Fritsch, Wolfgang Paster, Thomas Lion, Britta Eiz-Vesper, René Geyeregger
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAspergillus fumigatus (Asp) infections constitute a major cause of morbidity and mortality in patients following allogeneic hematopoietic stem cell transplantation (HSCT). In the context of insufficient host immunity, antifungal drugs sho
Externí odkaz:
https://doaj.org/article/e7579928abb04b849c28a29c88411a08
Autor:
Sabine Tischer-Zimmermann, Agnes Bonifacius, Maria Michela Santamorena, Philip Mausberg, Sven Stoll, Marius Döring, Ulrich Kalinke, Rainer Blasczyk, Britta Maecker-Kolhoff, Britta Eiz-Vesper
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIn immunocompromised patients, Epstein-Barr virus (EBV) infection or reactivation is associated with increased morbidity and mortality, including the development of B-cell lymphomas. The first-line treatment consists of reduction of immun
Externí odkaz:
https://doaj.org/article/a835f60d638343ba896921dd0b07be9b
Autor:
Katharina Schmalkuche, Reinhard Schwinzer, Nadine Wenzel, Emilio Valdivia, Björn Petersen, Rainer Blasczyk, Constanca Figueiredo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12711 (2023)
Xenotransplantation reemerged as a promising alternative to conventional transplantation enlarging the available organ pool. However, success of xenotransplantation depends on the design and selection of specific genetic modifications and on the deve
Externí odkaz:
https://doaj.org/article/c4edc1ab82cb4491b8444093493838fc