Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Rainald Knecht"'
Autor:
Christine Solbach, Anja Sterner-Kock, Marc Roller, Hans Georg Schnürch, Manfred Stegmuller, Gudrun Caspar-Bell, Petra Maria Schumm-Draeger, Manfred Kaufmann, Rainald Knecht
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 4, Iss 3, Pp 237-242 (2002)
The proliferative stimulus of the epidermal growth factor (EGF) in human epithelial cells is mediated by its binding to the external domain of the EGF receptor (EGF-R). The purpose of this study was to investigate whether growth arrest of tumors trea
Externí odkaz:
https://doaj.org/article/e5b4c80bffd642eead54784ce83170ac
Autor:
Mascha Binder, Carsten Bokemeyer, Sonja Loges, Boris Fehse, Kristoffer Riecken, Rainald Knecht, Martin Trepel, Bruno Märkl, Elzbieta Jakubowicz, Steffen Goletz, Antje Danielczyk, Simon Laban, Ingke Braren, Isabel Ben Batalla, Anja Thalhammer, Markus Sack, Veronique Blanchard, Karina Biskup, Tobias Grob, Beate Habel, Minna Voigtlaender, Malte Kriegs, Friederike Braig
Supplementary Figure 1. Inhibitory effect of Cetuximab determined by western blot analysis of 12 HNSCC cell line lysates. Supplementary Figure 2. Time course of EGFR phosphorylation in HNSCC cell line UT-SCC 8. Supplementary Figure 3. Correlation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2861dab98115ba59a2863d22258b88
https://doi.org/10.1158/0008-5472.22416219.v1
https://doi.org/10.1158/0008-5472.22416219.v1
Autor:
Mascha Binder, Carsten Bokemeyer, Sonja Loges, Boris Fehse, Kristoffer Riecken, Rainald Knecht, Martin Trepel, Bruno Märkl, Elzbieta Jakubowicz, Steffen Goletz, Antje Danielczyk, Simon Laban, Ingke Braren, Isabel Ben Batalla, Anja Thalhammer, Markus Sack, Veronique Blanchard, Karina Biskup, Tobias Grob, Beate Habel, Minna Voigtlaender, Malte Kriegs, Friederike Braig
Supplementary Table 1 Patient characteristics including EGFRK521 allele frequency. Supplementary Table 2 Characteristics and sequencing data of squamous cell carcinoma cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf07edc18e7ba91ca942179f80df7e1
https://doi.org/10.1158/0008-5472.22416216
https://doi.org/10.1158/0008-5472.22416216
Autor:
Mascha Binder, Carsten Bokemeyer, Sonja Loges, Boris Fehse, Kristoffer Riecken, Rainald Knecht, Martin Trepel, Bruno Märkl, Elzbieta Jakubowicz, Steffen Goletz, Antje Danielczyk, Simon Laban, Ingke Braren, Isabel Ben Batalla, Anja Thalhammer, Markus Sack, Veronique Blanchard, Karina Biskup, Tobias Grob, Beate Habel, Minna Voigtlaender, Malte Kriegs, Friederike Braig
Supplemental Figures 1 to 6 from Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-K521 Polymorphism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4bc16eeae53fa30a4b111b627183ce
https://doi.org/10.1158/0008-5472.22416222
https://doi.org/10.1158/0008-5472.22416222
Autor:
Mascha Binder, Carsten Bokemeyer, Sonja Loges, Boris Fehse, Kristoffer Riecken, Rainald Knecht, Martin Trepel, Bruno Märkl, Elzbieta Jakubowicz, Steffen Goletz, Antje Danielczyk, Simon Laban, Ingke Braren, Isabel Ben Batalla, Anja Thalhammer, Markus Sack, Veronique Blanchard, Karina Biskup, Tobias Grob, Beate Habel, Minna Voigtlaender, Malte Kriegs, Friederike Braig
Head and neck squamous cell carcinomas (HNSCC) exhibiting resistance to the EGFR-targeting drug cetuximab poses a challenge to their effective clinical management. Here, we report a specific mechanism of resistance in this setting based upon the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25965099290cbcc9845191154ace7fe
https://doi.org/10.1158/0008-5472.c.6509496.v1
https://doi.org/10.1158/0008-5472.c.6509496.v1
Autor:
Anja Thalhammer, Isabel Ben Batalla, Sonja Loges, Steffen Goletz, Tobias Grob, Karina Biskup, Beate Habel, Véronique Blanchard, Kristoffer Riecken, Markus Sack, Martin Trepel, Rainald Knecht, Friederike Braig, Ingke Braren, Carsten Bokemeyer, Mascha Binder, Boris Fehse, Antje Danielczyk, Elzbieta Jakubowicz, Simon Laban, Malte Kriegs, Bruno Märkl, Minna Voigtlaender
Publikováno v:
Cancer Research. 77:1188-1199
Head and neck squamous cell carcinomas (HNSCC) exhibiting resistance to the EGFR-targeting drug cetuximab poses a challenge to their effective clinical management. Here, we report a specific mechanism of resistance in this setting based upon the pres
Autor:
Thorsten Rieckmann, M.S. Kröger, J. Jensen, K Rothkamm, M Kriegs, Cordula Petersen, Rainald Knecht, F. Gatzemeier, CJ Busch
Publikováno v:
Radiotherapy and Oncology. 122:260-266
Background and purpose HPV-positive HNSCC cells are characterized by radiosensitivity, inefficient DNA double-strand break repair and a profound and prolonged arrest in G2. Here we explored the effect of clinically relevant inhibitors of Chk1 and Wee
Publikováno v:
HNO. 64:736-740
The annual meeting of the American Society of Clinical Oncology (ASCO) took place at the beginning of June 2016 in Chicago. This year a total of 28 studies on the treatment of patients with thyroid cancer were presented, described in this review arti
Publikováno v:
HNO. 64:717-722
Beim jahrlichen Treffen der American Society of Clinical Oncology (ASCO) wurden auch im Jahr 2016 aktuelle Studien zur Primartherapie von Kopf-Hals-Tumoren vorgestellt. Gegenstand der Untersuchungen sind v. a. Therapiestrategien fur lokal fortgeschri
Publikováno v:
HNO. 64:708-716
Die Immuntherapie erfahrt durch den Einsatz sog. Immuncheckpointinhibitoren aktuell auch eine Renaissance in der medikamentosen Kopf-Hals-Onkologie. Auf der aktuellen Jahrestagung der American Society of Clinical Oncology (ASCO) wurden zum Thema Immu