Circadian PERformance in breast cancer: a germline and somatic genetic study of PER3 VNTR polymorphisms and gene co-expression

Autor: Jaume Fores-Martos, Raimundo Cervera-Vidal, Julia Sierra-Roca, Carlos Lozano-Asencio, Vita Fedele, Sten Cornelissen, Hege Edvarsen, Irene Tadeo-Cervera, Pilar Eroles, Ana Lluch, Rafa Tabares-Seisdedos, Antonio Falcó, Laura J. Van’t Veer, Marjanka Schmidt, David A. Quigley, Anne-Lise Børresen-Dale, Vessela N. Kristensen, Allan Balmain, Joan Climent

Publikováno v: npj Breast Cancer, Vol 7, Iss 1, Pp 1-12 (2021)

Abstract Polymorphisms in the PER3 gene have been associated with several human disease phenotypes, including sleep disorders and cancer. In particular, the long allele of a variable number of tandem repeat (VNTR) polymorphism has been previously lin

Externí odkaz: https://doaj.org/article/4e917fb342074343a2b9ae2128ef604c

MicroRNAs as a clue to overcome breast cancer treatment resistance

Autor: Iris Garrido-Cano, Pilar Eroles, Birlipta Pattanayak, Raimundo Cervera, Ana Lameirinhas, Sandra Torres-Ruiz, Eduardo Tormo, Anna Adam-Artigues

Publikováno v: Cancer and Metastasis Reviews. 41:77-105

Breast cancer is the most frequent cancer in women worldwide. Despite the improvement in diagnosis and treatments, the rates of cancer relapse and resistance to therapies remain higher than desirable. Alterations in microRNAs have been linked to chan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2efc685c770470709d306586da48b175
https://doi.org/10.1007/s10555-021-09992-0

Abstract 1075: AXL is a potential druggable target in trastuzumab resistance in HER2+ breast cancer patients

Autor: Soraya Simón, Ana Rovira, Raimundo Cervera, Aleix Prat, Enrique J. Arenas, Pilar Eroles, Eduardo Tormo, Joaquín Arribas, Alex Martínez-Sabadell, Begoña Bermejo, M. I. Martínez, Octavio Burgues, Cristina Hernando, Fara Brasó-Maristany, Joan Albanell, Ana Lluch, Anna Adam-Artigues, Jesús Poveda, Federico Rojo, Juan Miguel Cejalvo

Publikováno v: Cancer Research. 81:1075-1075

Introduction HER2+ correlates with aggressive phenotype and poor prognosis. The use of several antiHER2 drugs has dramatically improved prognosis and survival of HER2+ breast cancer (BC) patients. However, ≈20% of these patients will present resist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d49932a1524c44e547790f024947b204
https://doi.org/10.1158/1538-7445.am2021-1075

List of Contributors

Autor: Carolina Abril-Tormo, Sahar Al-Mahdawi, Diogo Almeida-Rios, Sara Anjomani Virmouni, Juan Ausio, Bharati Bapat, Charlotte L. Bevan, Jenefer M. Blackwell, Tiziana Bonaldi, Abdelhalim Boukaba, Eoin Brennan, Enrique J. Busó, F. Javier Carmona Sanz, Raimundo Cervera, Alfredo Ciccodicola, Joan Climent, Valerio Costa, Ana B. Crujeiras, Alessandro Cuomo, Avery DeVries, Angel Diaz-Lagares, Roberta Esposito, Alessandro Fatica, Alfredo Ferro, Claire E. Fletcher, Ana-Maria Florea, Ernest Fraenkel, Yu Fujita, Tomohiro Fujiwara, Miriam Gagliardi, José Luis García-Giménez, Rosalba Giugno, Catherine Godson, Inês Graça, Kirsten Grønbæk, Shinji Hagiwara, Rui Henrique, José Santiago Ibañez Cabellos, Marisa Iborra, Toyotaka Ishibashi, Sarra E. Jamieson, Carmen Jerónimo, Sadhana Joshi, Phillip Kantharidis, Akira Kawai, Vinita Khot, Lasse Sommer Kristensen, Ana Lluch, José Antonio López-Guerrero, Paula Lopez-Serra, Annita Louloupi, Luca Magnani, Jacobo Martínez-Santamaría, Maria R. Matarazzo, Aaron McClelland, Pamela Milani, Yutaka Nezu, Roberta Noberini, Takahiro Ochiya, Toshifumi Ozaki, Federico V. Pallardó, Lorena Peiró-Chova, Marco Pellegrini, Tandy L.D. Petrov, Olga Bahamonde Ponce, Mark A. Pook, Alfredo Pulvirenti, João Ramalho-Carvalho, Alberto Ramos, George Rasti, Nicole C. Riddle, Peter H.J. Riegman, Carlos Romá Mateo, Francesco Russo, Fabian Sanchis-Gomar, Juan Sandoval, Flavia Scoyni, Marta Seco Cervera, Akifumi Shibakawa, Nicolas G. Simonet, Ailsa Sita-Lumsden, Olafur Andri Stefansson, Deepali Sundrani, Genevieve Syn, Trygve O. Tollefsbol, Eneda Toska, Marianne B. Treppendahl, Toshikazu Ushijima, Alejandro Vaquero, Donata Vercelli, Filipa Quintela Vieira, Yinan Zhang, Fang Zhao, Wilbert Zwart

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c0bf14fa23bfa54caa0990a65e44ff7
https://doi.org/10.1016/b978-0-12-801899-6.01002-0

A genomic approach to study down syndrome and cancer inverse comorbidity: untangling the chromosome 21

Autor: Enrique Chirivella, Raimundo Cervera-Vidal, Joan Climent, Alberto Ramos-Jarero, Jaume Forés-Martos

Publikováno v: Frontiers in Physiology
Frontiers in Physiology, Vol 6 (2015)

Down syndrome (DS), one of the most common birth defects and the most widespread genetic cause of intellectual disabilities, is caused by extra genetic material on chromosome 21 (HSA21). The increased genomic dosage of trisomy 21 is thought to be res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3528aec99e859151d14c43f764ea360a