Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Raimund Wagener"'
Autor:
Matthias Przyklenk, Shreya Karmacharya, Debora Bonasera, Arthur-Lauri Pasanen-Zentz, Stanislav Kmoch, Mats Paulsson, Raimund Wagener, Gianmaria Liccardi, Alvise Schiavinato
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract ANTXR1 is one of two cell surface receptors mediating the uptake of the anthrax toxin into cells. Despite substantial research on its role in anthrax poisoning and a proposed function as a collagen receptor, ANTXR1’s physiological function
Externí odkaz:
https://doaj.org/article/22356ec8dc874494a392ca8895a39007
Autor:
Helena Fabiana Forte-Gomez, Roberta Gioia, Francesca Tonelli, Birgit Kobbe, Peter Koch, Wilhelm Bloch, Mats Paulsson, Frank Zaucke, Antonella Forlino, Raimund Wagener
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
COMP (Cartilage Oligomeric Matrix Protein), also named thrombospondin-5, is a member of the thrombospondin family of extracellular matrix proteins. It is of clinical relevance, as in humans mutations in COMP lead to chondrodysplasias. The gene encodi
Externí odkaz:
https://doaj.org/article/9adb8056af46421082fccb017fb4d9a9
Autor:
Matthias Przyklenk, Stefanie Elisabeth Heumüller, Carolin Freiburg, Steffen Lütke, Gerhard Sengle, Manuel Koch, Mats Paulsson, Alvise Schiavinato, Raimund Wagener
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105116- (2022)
Summary: The microfibril-forming collagen VI is proteolytically cleaved and it was proposed that the released C-terminal Kunitz domain (C5) of the α3 chain is an adipokine important for tumor progression and fibrosis. Designated “endotrophin,” C
Externí odkaz:
https://doaj.org/article/a8b30b48a13a4e42ab42fd0c35ab3304
Autor:
Amelie T van der Ven, Birgit Kobbe, Stefan Kohl, Shirlee Shril, Hans-Martin Pogoda, Thomas Imhof, Hadas Ityel, Asaf Vivante, Jing Chen, Daw-Yang Hwang, Dervla M Connaughton, Nina Mann, Eugen Widmeier, Mary Taglienti, Johanna Magdalena Schmidt, Makiko Nakayama, Prabha Senguttuvan, Selvin Kumar, Velibor Tasic, Elijah O Kehinde, Shrikant M Mane, Richard P Lifton, Neveen Soliman, Weining Lu, Stuart B Bauer, Matthias Hammerschmidt, Raimund Wagener, Friedhelm Hildebrandt
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191224 (2018)
Congenital anomalies of the kidney and urinary tract (CAKUT) are the most common cause (40-50%) of chronic kidney disease (CKD) in children. About 40 monogenic causes of CAKUT have so far been discovered. To date less than 20% of CAKUT cases can be e
Externí odkaz:
https://doaj.org/article/2bc11b7231c74bacbf98e8696e293ebc
Autor:
Peter A. Bell, Raimund Wagener, Frank Zaucke, Manuel Koch, Julian Selley, Stacey Warwood, David Knight, Raymond P. Boot-Handford, David J. Thornton, Michael D. Briggs
Publikováno v:
Biology Open, Vol 2, Iss 8, Pp 802-811 (2013)
Summary Pseudoachondroplasia and multiple epiphyseal dysplasia are genetic skeletal diseases resulting from mutations in cartilage structural proteins. Electron microscopy and immunohistochemistry previously showed that the appearance of the cartilag
Externí odkaz:
https://doaj.org/article/7dede92b37ab4afaad40a786ac0bbdf0
Autor:
Sandra Lettmann, Wilhelm Bloch, Tobias Maaß, Anja Niehoff, Jan-Niklas Schulz, Beate Eckes, Sabine A Eming, Paolo Bonaldo, Mats Paulsson, Raimund Wagener
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105686 (2014)
Patients suffering from collagen VI related myopathies caused by mutations in COL6A1, COL6A2 and COL6A3 often also display skin abnormalities, like formation of keloids or "cigarette paper" scars, dry skin, striae rubrae and keratosis pilaris (follic
Externí odkaz:
https://doaj.org/article/86af229f60434120a026ce2496335d9c
Autor:
Thomas J Carney, Natália Martins Feitosa, Carmen Sonntag, Krasimir Slanchev, Johannes Kluger, Daiji Kiyozumi, Jan M Gebauer, Jared Coffin Talbot, Charles B Kimmel, Kiyotoshi Sekiguchi, Raimund Wagener, Heinz Schwarz, Phillip W Ingham, Matthias Hammerschmidt
Publikováno v:
PLoS Genetics, Vol 6, Iss 4, p e1000907 (2010)
Using forward genetics, we have identified the genes mutated in two classes of zebrafish fin mutants. The mutants of the first class are characterized by defects in embryonic fin morphogenesis, which are due to mutations in a Laminin subunit or an In
Externí odkaz:
https://doaj.org/article/9c7e24b095e0436ea5c7ffdc952f4b05
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6782
AMACO (VWA2 protein), secreted by epithelial cells, is strongly expressed at basement membranes when budding or invagination occurs in embryos. In skin, AMACO associates with proteins of the Fraser complex, which form anchoring cords. These, during d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b66cc8ff28d9b980ae23ecb311832cb
https://doi.org/10.3390/ijms24076782
https://doi.org/10.3390/ijms24076782
Autor:
Wilhelm Bloch, Juliane Heilig, Raimund Wagener, D. Shmerling, Anja Niehoff, P. Seifer, Frank Zaucke, Attila Aszodi, Lutz Fleischhauer, Martine Cohen-Solal, S. Sonntag, Eric Haÿ, Hauke Clausen-Schaumann, Mats Paulsson
Publikováno v:
Osteoarthritis and Cartilage. 29:78-88
Summary Objective The human matrilin-3 T303M (in mouse T298M) mutation has been proposed to predispose for osteoarthritis, but due to the lack of an appropriate animal model this hypothesis could not be tested. This study was carried out to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1d0bde69db1e49aaabcc5e205a18a1
https://doi.org/10.1016/j.joca.2020.09.008
https://doi.org/10.1016/j.joca.2020.09.008
Publikováno v:
European Journal of Immunology. 51:2345-2347
The monoclonal antibody ER-TR7 was used in a great number of studies for detecting reticular fibroblasts and the ECM of lymphoid and non-lymphoid organs even if the protein recognized by the ER-TR7 antibody was not known. We have now identified nativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84874e71637fd480ff13d55cc1cf8580
https://doi.org/10.1002/eji.202149263
https://doi.org/10.1002/eji.202149263