Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Raimund Jung"'
Autor:
Raimund Jung, Marie C Lechler, Ana Fernandez-Villegas, Chyi Wei Chung, Harry C Jones, Yoon Hee Choi, Maximilian A Thompson, Christian Rödelsperger, Waltraud Röseler, Gabriele S Kaminski Schierle, Ralf J Sommer, Della C David
Publikováno v:
PLoS Biology, Vol 21, Iss 9, p e3002284 (2023)
During aging, proteostasis capacity declines and distinct proteins become unstable and can accumulate as protein aggregates inside and outside of cells. Both in disease and during aging, proteins selectively aggregate in certain tissues and not other
Externí odkaz:
https://doaj.org/article/6e413ad3f27943b5974f39bac00f3cda
Autor:
Chiara Zambarda, Carlos Pérez González, Andreas Schoenit, Nisha Veits, Clara Schimmer, Raimund Jung, Dirk Ollech, Joel Christian, Pere Roca-Cusachs, Xavier Trepat, Elisabetta Ada Cavalcanti-Adam
Publikováno v:
European Journal of Cell Biology, Vol 101, Iss 4, Pp 151274- (2022)
Several factors present in the extracellular environment regulate epithelial cell adhesion and dynamics. Among them, growth factors such as EGF, upon binding to their receptors at the cell surface, get internalized and directly activate the acto-myos
Externí odkaz:
https://doaj.org/article/a7aecba09d4e4db0843a78412505db80
Autor:
Marie C. Lechler, Emily D. Crawford, Nicole Groh, Katja Widmaier, Raimund Jung, Janine Kirstein, Jonathan C. Trinidad, Alma L. Burlingame, Della C. David
Publikováno v:
Cell Reports, Vol 18, Iss 2, Pp 454-467 (2017)
Summary: Low-complexity “prion-like” domains in key RNA-binding proteins (RBPs) mediate the reversible assembly of RNA granules. Individual RBPs harboring these domains have been linked to specific neurodegenerative diseases. Although their aggre
Externí odkaz:
https://doaj.org/article/b5d785eb2438408095c363dff5f3c2d9
Autor:
Chaolie Huang, Sara Wagner-Valladolid, Amberley D Stephens, Raimund Jung, Chetan Poudel, Tessa Sinnige, Marie C Lechler, Nicole Schlörit, Meng Lu, Romain F Laine, Claire H Michel, Michele Vendruscolo, Clemens F Kaminski, Gabriele S Kaminski Schierle, Della C David
Publikováno v:
eLife, Vol 8 (2019)
Reduced protein homeostasis leading to increased protein instability is a common molecular feature of aging, but it remains unclear whether this is a cause or consequence of the aging process. In neurodegenerative diseases and other amyloidoses, spec
Externí odkaz:
https://doaj.org/article/d304ea99735c4d8ea67842213713ac7f
Autor:
Anna Katharina Maier, Raimund Jung, Clarissa Villinger, Axel Schubert, Paul Walther, Christian Sinzger, Diana Lieber
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169580 (2017)
Widely used methods for quantification of human cytomegalovirus (HCMV) infection in cell culture such as immunoblotting or plaque reduction assays are generally restricted to low throughput and require time-consuming evaluation. Up to now, only few H
Externí odkaz:
https://doaj.org/article/c831f8802df14645a494c997d25aa2cb
Autor:
Ralf J. Sommer, Christian Rödelsperger, Raimund Jung, Waltraud Röseler, Marie C. Lechler, Della C. David
During aging, proteostasis capacity declines and aggregation-prone proteins become instable, accumulating in protein aggregates both inside and outside cells. Both in disease and during aging, proteins selectively aggregate in certain tissues and not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5f85266c1300da9443ab3b2852ca657
https://doi.org/10.1101/2020.12.04.409771
https://doi.org/10.1101/2020.12.04.409771
Autor:
Raimund Jung, Waltraud Röseler, Sinem Agilkaya, Ivan Gallotta, Martin Haslbeck, Ralf J. Sommer, Della C. David, Christian Rödelsperger, Chaolie Huang, Jane L. Blersch, Aneet Sandhu, Maximilian Peters
Publikováno v:
Nature / Physical science 584(7821), 410-414 (2020). doi:10.1038/s41586-020-2461-z
In metazoans, the secreted proteome participates in intercellular signalling and innate immunity, and builds the extracellular matrix scaffold around cells. Compared with the relatively constant intracellular environment, conditions for proteins in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7551d1df24598615d1d5f8f956f7e582
Autor:
Marie C. Lechler, Claire H. Michel, G. S. Kaminski Schierle, Chaolie Huang, Raimund Jung, Chetan Poudel, Clemens F. Kaminski, Della C. David, N. Schlörit, A.D. Stephens, Michele Vendruscolo, Romain F. Laine, Tessa Sinnige, Sara Wagner-Valladolid
Reduced protein homeostasis and increased protein instability is a common feature of aging. Yet it remains unclear whether protein instability is a cause of aging. In neurodegenerative diseases and amyloidoses, specific proteins self-assemble into am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3f0aaba92d0d8b1562dd9e98d11e31
Publikováno v:
Journal of Visualized Experiments.
In the last decades, the prevalence of neurodegenerative disorders, such as Alzheimer's disease (AD) and Parkinson's disease (PD), has grown. These age-associated disorders are characterized by the appearance of protein aggregates with fibrillary str
Autor:
Janine Kirstein, Katja Widmaier, Jonathan C. Trinidad, Marie C. Lechler, Emily D. Crawford, Della C. David, Nicole Groh, Alma L. Burlingame, Raimund Jung
Publikováno v:
Cell reports 18(2), 454-467 (2017). doi:10.1016/j.celrep.2016.12.033
Cell Reports
Cell reports, 18(2): 454–467
Cell Reports, Vol 18, Iss 2, Pp 454-467 (2017)
Cell Reports
Cell reports, 18(2): 454–467
Cell Reports, Vol 18, Iss 2, Pp 454-467 (2017)
Summary Low-complexity “prion-like” domains in key RNA-binding proteins (RBPs) mediate the reversible assembly of RNA granules. Individual RBPs harboring these domains have been linked to specific neurodegenerative diseases. Although their aggreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5af5e2785ae020a809f32fa789c3e4