Zobrazeno 1 - 10
of 238
pro vyhledávání: '"Raimund J Ober"'
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218931 (2019)
Endosomes are subcellular organelles which serve as important transport compartments in eukaryotic cells. Fluorescence microscopy is a widely applied technology to study endosomes at the subcellular level. In general, a microscopy image can contain a
Externí odkaz:
https://doaj.org/article/30319e57322942ecb91c403d1acdbeb0
Autor:
E. Sally eWard, Raimund J Ober
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
Externí odkaz:
https://doaj.org/article/247ec7e6cd4249e6baab6d760381df34
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134112 (2015)
The localization of fluorescent microspheres is often employed for drift correction and image registration in single molecule microscopy, and is commonly carried out by fitting a point spread function to the image of the given microsphere. The mismat
Externí odkaz:
https://doaj.org/article/d9bc92343ef4449db45fbb87db17b524
Autor:
Priyanka Khare, Wei Sun, Sreevidhya Ramakrishnan, Rafal Swiercz, Guiyang Hao, Su-Tang Lo, Kien Nham, Xiankai Sun, Raimund J. Ober, E. Sally Ward
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
The prolonged in vivo persistence of antibodies results in high background and poor contrast during their use as molecular imaging agents for positron emission tomography (PET). We have recently described a class of engineered Fc fusion proteins that
Externí odkaz:
https://doaj.org/article/01533df49adc49dc80bf69cd741c757d
Two-color live cell imaging of a J774A.1 macrophage phagocytosing MDA-MB-453 cancer cells. Macrophages with surface-labeled CD45 (green) engulf three trastuzumab-opsonized MDA-MB-453 cells (red). Time is indicated at the top left in minutes:seconds f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb6bad3220ce20d8ba2f3fb507d1c32
https://doi.org/10.1158/1535-7163.22506069.v1
https://doi.org/10.1158/1535-7163.22506069.v1
Autor:
E. Sally Ward, Raimund J. Ober, Ralph P. Mason, Alan Schroit, Hong Tian, Siva Charan Devanaboyina, David Kim, Ramraj Velmurugan, Dongyoung Kim, Li Li, Srinivas Chiguru, Ran Li
In response to cellular stress, phosphatidylserine is exposed on the outer membrane leaflet of tumor blood vessels and cancer cells, motivating the development of phosphatidylserine-specific therapies. The generation of drug-conjugated phosphatidylse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92085005f8e6d9ef756fbc970e4cdd26
https://doi.org/10.1158/1535-7163.c.6537763
https://doi.org/10.1158/1535-7163.c.6537763
Autor:
E. Sally Ward, Raimund J. Ober, Ralph P. Mason, Alan Schroit, Hong Tian, Siva Charan Devanaboyina, David Kim, Ramraj Velmurugan, Dongyoung Kim, Li Li, Srinivas Chiguru, Ran Li
Document containing supplementary figures; Figure S1. Gel filtration analyses of recombinant Fc fusions; Figure S2. Exposure of PS by tumor endothelial cells; Figure S3. Subcellular trafficking analyses of bivalent and tetravalent Fc-Syt1 fusions; Fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e929a64f1b2ecb0ab1ea61b9ebb23d
https://doi.org/10.1158/1535-7163.22504528.v1
https://doi.org/10.1158/1535-7163.22504528.v1
Document containing supplementary methods, supplementary figure legends for supplementary movies and figures; Figure S1. Harvesting efficiency of cancer cells in macrophage:cancer cell co-cultures; Figure S2. Macrophage-mediated reduction of opsonize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285e9703e3d7d65438339efc3723743e
https://doi.org/10.1158/1535-7163.22506051.v1
https://doi.org/10.1158/1535-7163.22506051.v1
Publikováno v:
Ieee Transactions on Computational Imaging
The advent of single molecule microscopy has rev- olutionized biological investigations by providing a powerful tool for the study of intercellular and intracellular trafficking processes of protein molecules which was not available before through co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ce2651771b8e7c34d3779eba85097c
http://europepmc.org/articles/PMC7879562
http://europepmc.org/articles/PMC7879562
Assessing the quality of parameter estimates for models describing the motion of single molecules in cellular environments is an important problem in fluorescence microscopy. In this work, we consider the fundamental data model, where molecules emit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1341f721ccb56bee6626c4c7d9eaeeee
https://eprints.soton.ac.uk/455856/
https://eprints.soton.ac.uk/455856/