Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Raimund I Herzog"'
Autor:
Seung Hee Lee, Suho Lee, Jing Du, Kanika Jain, Min Ding, Anis J Kadado, Gourg Atteya, Zainab Jaji, Tarun Tyagi, Won‐ho Kim, Raimund I Herzog, Amar Patel, Costin N Ionescu, Kathleen A Martin, John Hwa
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 8, Pp 1-16 (2019)
Abstract Mitophagy can selectively remove damaged toxic mitochondria, protecting a cell from apoptosis. The molecular spatial–temporal mechanisms governing autophagosomal selection of reactive oxygen species (ROS)‐damaged mitochondria, particular
Externí odkaz:
https://doaj.org/article/871e1a76b48e41b29fd1dc521e9e776c
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69464 (2013)
To develop a vaccination approach for prevention of type 1 diabetes (T1D) that selectively attenuates self-reactive T-cells targeting specific autoantigens, we selected phage-displayed single chain antigen receptor libraries for clones binding to a c
Externí odkaz:
https://doaj.org/article/67e6968de23148c1b87adf0deb7e3322
Autor:
Victoria Cotero, John Graf, Hiromi Miwa, Zall Hirschstein, Khaled Qanud, Tomás S. Huerta, Ningwen Tai, Yuyan Ding, Kevin Jimenez-Cowell, Jacquelyn N. Tomaio, Weiguo Song, Alex Devarajan, Tea Tsaava, Radhika Madhavan, Kirk Wallace, Evelina Loghin, Christine Morton, Ying Fan, Tzu-Jen Kao, Kainat Akhtar, Meghana Damaraju, Linda Barenboim, Teresa Maietta, Jeffrey Ashe, Kevin J. Tracey, Thomas R. Coleman, Dino Di Carlo, Damian Shin, Stavros Zanos, Sangeeta S. Chavan, Raimund I. Herzog, Chris Puleo
Publikováno v:
Nature biomedical engineering, vol 6, iss 6
Nat Biomed Eng
Nat Biomed Eng
Peripheral neurons that sense glucose relay signals of glucose availability to integrative clusters of neurons in the brain. However, the roles of such signalling pathways in the maintenance of glucose homoeostasis and their contribution to disease a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0a8488343d3d4ec60241759abde0f4
https://escholarship.org/uc/item/3w48p6zz
https://escholarship.org/uc/item/3w48p6zz
Autor:
Qunxiang Ong, Yongzhan Nie, Mingzuo Jiang, Kaisi Zhang, Weiming Ni, Hai Bin Ruan, Raimund I. Herzog, Weiping Han, Jeong Sang Lee, Xiaoyong Yang, Kamini Singh, Xuemei Han, Robert S. Sherwin, Zhaobing Ding, Susan M. Kaech, Philip Lee, Jing Wu, Jinfeng Zhou, Min-Dian Li, Kevin Qian, Hans-Guido Wendel, John R. Yates, Bichen Zhang, Jay Prakash Singh
Publikováno v:
Oncogene
Cancer cells are known to adopt aerobic glycolysis in order to fuel tumor growth, but the molecular basis of this metabolic shift remains largely undefined. O-GlcNAcase (OGA) is an enzyme harboring O-linked β-N-acetylglucosamine (O-GlcNAc) hydrolase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9baa90f20539dfbf10cedd4f61381a
https://doi.org/10.1038/s41388-019-0975-3
https://doi.org/10.1038/s41388-019-0975-3
Publikováno v:
Children
Volume 7
Issue 12
Children, Vol 7, Iss 270, p 270 (2020)
Volume 7
Issue 12
Children, Vol 7, Iss 270, p 270 (2020)
Preliminary evidence suggests that the glutamate&ndash
serine&ndash
glycine (GSG) index, which combines three amino acids involved in glutathione synthesis, may be used as a potential biomarker of non-alcoholic fatty liver disease (NAFLD).
serine&ndash
glycine (GSG) index, which combines three amino acids involved in glutathione synthesis, may be used as a potential biomarker of non-alcoholic fatty liver disease (NAFLD).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7aae14b06f9e097ca5d4c2f19cae028
Autor:
Yaozu Xiang, John Hwa, Li Qian, Seung Hee Lee, Chaoying Yin, Kai Jiang, Kathleen A. Martin, Dandan Wang, Yu Liao, Jing Du, Zizhuo Tu, Li Wang, Lawrence H. Young, Feng Chen, Hongcai Shang, Xiaoyue Hu, Zejian Liu, Raimund I. Herzog
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • Optimal treatment for patients with diabetes and myocardial infarction remains a challenge. • Hyperglycemia- and hyperinsulinemia-induced miR-24 reduction and O-GlcNAcylation in the diabetic heart contributes to
Highlights • Optimal treatment for patients with diabetes and myocardial infarction remains a challenge. • Hyperglycemia- and hyperinsulinemia-induced miR-24 reduction and O-GlcNAcylation in the diabetic heart contributes to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3307bc13385b89107136b2007ea8c0
https://doi.org/10.1016/j.jacbts.2018.01.005
https://doi.org/10.1016/j.jacbts.2018.01.005
Autor:
Mridu Gulati, Wajahat Z. Mehal, Jaden Faunce, Caitlin Brandsdorfer, Jose D. Herazo-Maya, Varvara Kirillov, Jonathan Puchalski, Daniel F Bogenhagen, Christina Blaul, Erica L. Herzog, Anjelica L. Gonzalez, Glenda Trujillo, Raimund I. Herzog, Kathleen O. Lindell, Martin D. Slade, Huanxing Sun, Changwan Ryu, Kevin F. Gibson, Naftali Kaminski, Yonglin Chen, Julia Winkler, Argyrios Tzouvelekis, Danielle Antin-Ozerkis, Tony Woolard, Hongyi Pan, Carol Feghali-Bostwick, Charles S. Dela Cruz, Awo Osafo-Addo
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 196:1571-1581
Idiopathic pulmonary fibrosis (IPF) involves the accumulation of α-smooth muscle actin-expressing myofibroblasts arising from interactions with soluble mediators such as transforming growth factor-β1 (TGF-β1) and mechanical influences such as loca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f90a6beadf9cbd20558ef60e6ea3f3
https://doi.org/10.1164/rccm.201612-2480oc
https://doi.org/10.1164/rccm.201612-2480oc
Autor:
Dennis W. J. Klomp, Raimund I. Herzog, Bart R. Steensma, Graeme F. Mason, Robin A. de Graaf, Douglas L. Rothman, Peter B. Brown, Henk M. De Feyter
Publikováno v:
Magnetic Resonance in Medicine. 80:11-20
Purpose 13 C magnetic resonance spectroscopy (MRS) in combination with infusion of 13 C-labeled substrates has led to unique insights into human brain metabolism and neurotransmitter cycling. However, the low sensitivity of direct 13 C MRS and high r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b760c2cf477e6186dfb6637eaf339a77
https://doi.org/10.1002/mrm.27003
https://doi.org/10.1002/mrm.27003
Autor:
Cosimo Giannini, Nicola Santoro, Raimund I. Herzog, Fangyong Li, Hetty Prinsen, Robin A. de Graaf, Sonia Caprio, Domenico Tricò, Christoph Juchem
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 102:2473-2481
Context Traditional risk factors for type 2 diabetes mellitus are weak predictors of changes in glucose tolerance and insulin sensitivity in youth. Objective To identify early metabolic features of insulin resistance (IR) in youth and whether they pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b5be4e3b7dc42549a0775c5fe2ce2b
https://doi.org/10.1210/jc.2017-00475
https://doi.org/10.1210/jc.2017-00475
Autor:
Ryan D. Molony, Caroline J. Zeiss, Vishwa Deep Dixit, Akiko Iwasaki, Jennifer L. Asher, Ludmilla A. Morozova-Roche, Chao Wang, Raimund I. Herzog, Albert C. Shaw, Emily L. Goldberg
Publikováno v:
Cell Reports, Vol 18, Iss 9, Pp 2077-2087 (2017)
Summary: Aging and lipotoxicity are two major risk factors for gout that are linked by the activation of the NLRP3 inflammasome. Neutrophil-mediated production of interleukin-1β (IL-1β) drives gouty flares that cause joint destruction, intense pain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f72994d2c9006ce812ff5bbe7007af
https://doi.org/10.1016/j.celrep.2017.02.004
https://doi.org/10.1016/j.celrep.2017.02.004