Zobrazeno 1 - 10
of 220
pro vyhledávání: '"Raimond L, Winslow"'
Autor:
Yvette Tan, Michael Young, Akanksha Girish, Beini Hu, Zina Kurian, Joseph L. Greenstein, Han Kim, Raimond L Winslow, James Fackler, Jules Bergmann
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Mechanical ventilation is a life-saving treatment in the Intensive Care Unit (ICU), but often causes patients to be at risk of further respiratory complication. We created a statistical model utilizing electronic health record and physi
Externí odkaz:
https://doaj.org/article/8b2d9932ef1f45a09107fa28a5765e26
Autor:
Sanjukta N Bose, Andrew Defante, Joseph L Greenstein, Gabriel G Haddad, Julie Ryu, Raimond L Winslow
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0289763 (2023)
RationaleAcute respiratory failure is a life-threatening clinical outcome in critically ill pediatric patients. In severe cases, patients can require mechanical ventilation (MV) for survival. Early recognition of these patients can potentially help c
Externí odkaz:
https://doaj.org/article/3fd648cbe4c84890b991ebce35b06498
Autor:
Michael I. Miller, Andrew O. Brightman, Frederick H. Epstein, K. Jane Grande-Allen, Jordan J. Green, Eileen Haase, Cato T. Laurencin, Elizabeth Logsdon, Feilim Mac Gabhann, Brenda Ogle, Chun Wang, George R. Wodicka, Raimond L. Winslow
Publikováno v:
BME Frontiers, Vol 4 (2023)
Externí odkaz:
https://doaj.org/article/ba6d717ecabe4bddba4317861f28bbf8
Autor:
Akshaya V Annapragada, Joseph L Greenstein, Sanjukta N Bose, Bradford D Winters, Sridevi V Sarma, Raimond L Winslow
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 12, p e1009712 (2021)
Hypoxemia is a significant driver of mortality and poor clinical outcomes in conditions such as brain injury and cardiac arrest in critically ill patients, including COVID-19 patients. Given the host of negative clinical outcomes attributed to hypoxe
Externí odkaz:
https://doaj.org/article/3746b8c908d3497fb4dec5a63de0bd00
Autor:
Joshua A. Krachman, Jessica A. Patricoski, Christopher T. Le, Jina Park, Ruijing Zhang, Kirby D. Gong, Indranuj Gangan, Raimond L. Winslow, Joseph L. Greenstein, James Fackler, Anthony A. Sochet, Jules P. Bergmann
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Background: High flow nasal cannula (HFNC) is commonly used as non-invasive respiratory support in critically ill children. There are limited data to inform consensus on optimal device parameters, determinants of successful patient response, and indi
Externí odkaz:
https://doaj.org/article/936a3e40619c4397af3d8200c68880d5
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 10, p e1009536 (2021)
Ectopic beats (EBs) are cellular arrhythmias that can trigger lethal arrhythmias. Simulations using biophysically-detailed cardiac myocyte models can reveal how model parameters influence the probability of these cellular arrhythmias, however such an
Externí odkaz:
https://doaj.org/article/477112a02f4f479683219e2e669f6343
Autor:
Sanjukta N. Bose, Joseph L. Greenstein, James C. Fackler, Sridevi V. Sarma, Raimond L. Winslow, Melania M. Bembea
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Objective: The objective of the study is to build models for early prediction of risk for developing multiple organ dysfunction (MOD) in pediatric intensive care unit (PICU) patients.Design: The design of the study is a retrospective observational co
Externí odkaz:
https://doaj.org/article/8a57a99685bf432795438e5d3045306f
Autor:
Ran Liu, BS, Joseph L. Greenstein, PhD, James C. Fackler, MD, Jules Bergmann, MD, Melania M. Bembea, MD, MPH, PhD, Raimond L. Winslow, PhD
Publikováno v:
Critical Care Explorations, Vol 3, Iss 6, p e0442 (2021)
Objectives:. Sepsis and septic shock are leading causes of in-hospital mortality. Timely treatment is crucial in improving patient outcome, yet treatment delays remain common. Early prediction of those patients with sepsis who will progress to its mo
Externí odkaz:
https://doaj.org/article/1daf61f35ab0440597d1a78e8c215442
Autor:
Aman Ullah, Minh Tuan Hoang-Trong, William Jonathan Lederer, Raimond L. Winslow, Mohsin Saleet Jafri
Publikováno v:
Cells, Vol 11, Iss 12, p 1878 (2022)
Cardiovascular disease is the leading cause of death worldwide due in a large part to arrhythmia. In order to understand how calcium dynamics play a role in arrhythmogenesis, normal and dysfunctional Ca2+ signaling in a subcellular, cellular, and tis
Externí odkaz:
https://doaj.org/article/cd09b38068bb406e83b57392a1db191f
Publikováno v:
eLife, Vol 9 (2020)
Sepsis is not a monolithic disease, but a loose collection of symptoms with diverse outcomes. Thus, stratification and subtyping of sepsis patients is of great importance. We examine the temporal evolution of patient state using our previously-publis
Externí odkaz:
https://doaj.org/article/f5c216a9c58b49f4bc42633fe53816f8