Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Raimon Duran-Struuck"'
Autor:
Monica Wei, Laurice Flowers, Simon A. B. Knight, Qi Zheng, Sofia Murga-Garrido, Aayushi Uberoi, Jamie Ting-Chun Pan, Jasmine Walsh, Erin Schroeder, Emily W. Chu, Amy Campbell, Daniel Shin, Charles W. Bradley, Raimon Duran-Struuck, Elizabeth A. Grice
Publikováno v:
mSphere, Vol 8, Iss 4 (2023)
ABSTRACT The microbiota mediate multiple aspects of skin barrier function, including colonization resistance to pathogens such as Staphylococcus aureus. The endogenous skin microbiota limits S. aureus colonization via competition and direct inhibitio
Externí odkaz:
https://doaj.org/article/686198a86f14431a9493458327c5a513
Autor:
Gavin I. Ellis, Mosha Z. Deng, Delaine W. Winn, Kimberly E. Coker, Divanshu Shukla, Vijay Bhoj, Michael C. Milone, Raimon Duran-Struuck, James L. Riley
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101784- (2022)
Summary: It is technically challenging to generate large doses of regulatory T cells (Tregs) engineered to express a chimeric antigen receptor (CAR) in non-human primates (NHP). Here, we have optimized the manufacturing of CAR Tregs by stringent sort
Externí odkaz:
https://doaj.org/article/3ecb14d2484749ee86dcbdacea509bb5
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The absence of clinically relevant large animal tumor models has historically forced experimental cellular therapies for hematological malignancies to translate directly from murine models to clinical trials. However, recent advances highlight swine
Externí odkaz:
https://doaj.org/article/f954b604cdac4fdda70dfb17ef957216
Autor:
Marian Schenk, Abraham J. Matar, Isabel Hanekamp, Robert J. Hawley, Christene A. Huang, Raimon Duran-Struuck
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The lack of a reliable and reproducible large animal tumor model for the study of hemolymphatic malignancies limits the ability to explore the underlying pathophysiology and testing of novel therapies. The goal of this study was to develop an aggress
Externí odkaz:
https://doaj.org/article/088b3ccbf7024b20b7aed9c7f0af87f2
Publikováno v:
Transplantation. 106:928-937
Over the last 40 y, a specialized herd of miniature swine has been intentionally bred to develop lines of animals homozygous for the swine major histocompatibility complex (MHC), which have facilitated transplantation studies across reproducible MHC
Publikováno v:
Transplantation and Cellular Therapy. 29:S185-S186
Autor:
Laurice Flowers, Monica Wei, Simon A. B. Knight, Qi Zheng, Aayushi Uberoi, Amy Campbell, Ting-Chun Jamie Pan, Jasmine Walsh, Erin Schroeder, Emily W. Chu, Charles W. Bradley, Raimon Duran-Struuck, Elizabeth A. Grice
The microbiota mediates multiple aspects of skin barrier function, including colonization resistance to pathogens such as Staphylococcus aureus. The endogenous skin microbiota limits S. aureus colonization via competition and direct inhibition. Novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::486d481834fce22470124f298efde822
https://doi.org/10.1101/2022.08.05.502505
https://doi.org/10.1101/2022.08.05.502505
Autor:
Brian Karolewski, Joshua Weiner, Adam Griesemer, Sulemon Chaudhry, Megan Sykes, Sam W. Baker, Philipp J. Houck, Yojiro Kato, Jonah Zitsman, Anette Wu, Tomoaki Kato, Mallory L. Sears, Paula Alonso-Guallart, Raimon Duran-Struuck, Jay H. Lefkowitch, Mercedes Martinez, David C. Woodland, Hugo P. Sondermeijer
Publikováno v:
Transplantation
Background Although short-term outcomes for liver transplantation have improved, patient and graft survival are limited by infection, cancer, and other complications of immunosuppression. Rapid induction of tolerance after liver transplantation would
Publikováno v:
Transplant immunology. 68
Acute rejection is a leading cause of organ transplant failure and the most common indication for re-transplantation. Clinically, suspicion of acute rejection is often dependent upon serum laboratory values which may only manifest after organ injury.
Autor:
Sigal Kofman, Jonah Zitsman, Megan Sykes, Jeffrey Stern, David C. Woodland, Siu Hong Ho, Leo Buhler, Adam Griesemer, Paula Alonso-Guallart, Raimon Duran-Struuck, Hugo P. Sondermeijer
Publikováno v:
Am J Transplant
American Journal of Transplantation, 19(8), 2186-2198. Wiley
American Journal of Transplantation, 19(8), 2186-2198. Wiley
Reliable in vitro expansion protocols of regulatory T cells (Tregs) are needed for clinical use. We studied the biology of Mauritian Cynomolgus macaque (MCM) Tregs and developed four in vitro Treg expansion protocols for translational studies. Tregs