Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Raimo A, Ketola"'
Autor:
Pirkko Kriikku, Raimo A. Ketola
Publikováno v:
Drug Testing and Analysis. 11:1338-1357
A meta-analysis of drug concentrations in post-mortem specimens is presented. The analysis involved 50 commonly used drugs and their concentrations in femoral blood, other blood (such as cardiac blood), vitreous humor, muscle, liver, kidney, brain, h
Autor:
Ilkka Ojanperä, Raimo A. Ketola
Publikováno v:
Drug Testing and Analysis. 11:1326-1337
Concentration distributions for 183 drugs and metabolites frequently found in post-mortem (PM) femoral venous blood were statistically characterized based on an extensive database of 122 234 autopsy cases investigated during an 18-year period in a ce
Autor:
Tina Suominen, Päivi Uutela, Raimo A Ketola, Jonas Bergquist, Lars Hillered, Moshe Finel, Hongbo Zhang, Aki Laakso, Risto Kostiainen
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e68007 (2013)
An UPLC-MS/MS method was developed for the determination of serotonin (5-HT), dopamine (DA), their phase I metabolites 5-HIAA, DOPAC and HVA, and their sulfate and glucuronide conjugates in human brain microdialysis samples obtained from two patients
Externí odkaz:
https://doaj.org/article/7902cbc36bd84fa68c5c70db7f5f89ce
Autor:
Julia Lehtinen, Mari Raki, Kim A Bergström, Päivi Uutela, Katariina Lehtinen, Annukka Hiltunen, Jere Pikkarainen, Huamin Liang, Sari Pitkänen, Ann-Marie Määttä, Raimo A Ketola, Marjo Yliperttula, Thomas Wirth, Arto Urtti
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41410 (2012)
BACKGROUND: Epidermal growth factor receptor (EGFR) is overexpressed in many solid tumor types, such as ovarian carcinoma. Immunoliposome based drug targeting has shown promising results in drug delivery to the tumors. However, the ratio of tumor-to-
Externí odkaz:
https://doaj.org/article/503018bf1f2148a89d56c2f7c458ea89
Autor:
Merja Gergov, Raimo A. Ketola
Publikováno v:
Forensic Toxicology. 34:235-243
A liquid chromatography-tandem mass spectrometric (LC-MS/MS) method was developed and validated for the analysis of seven common sartans (candesartan, eprosartan, losartan, olmesartan, telmisartan, valsartan, and losartan carboxylic acid (EXP3174), t
Publikováno v:
Rapid Communications in Mass Spectrometry. 30:467-475
Rationale Fast methods that allow the in situ analysis of explosives from a variety of surfaces are needed in crime scene investigations and home-land security. Here, the feasibility of the ambient mass spectrometry technique desorption atmospheric p
Publikováno v:
Forensic Science International. 249:e7-e11
Kavalactones are a group of compounds found in kava, a beverage or extract prepared from the rhizome of the kava plant (Piper methysticum). Traditionally kava extracts have been used for their anxiolytic and sedative properties. Sales of kava extract
Publikováno v:
Journal of Analytical Toxicology. 39:359-364
This work describes a procedure to evaluate matrix effects in a combined dilution and standard addition method (SAM) using liquid chromatography-electrospray-tandem mass spectrometry. The method was validated and applied to an analysis of metformin i
Publikováno v:
Drug Testing and Analysis. 7:89-94
A phenyethylamine derivative, 2-amino-N-ethyl-1-phenylbutane (2-AEPB), has recently been detected in doping control and drugs-of-abuse samples, and identified as a non-labelled ingredient in a dietary supplement. To facilitate efficient control of th
Publikováno v:
Analytica Chimica Acta. 794:76-81
A new and simple APPI interface employing commercially available hardware is used to combine GC to MS. The feasibility of the method is demonstrated in the analysis of urine samples for neurosteroids as their trimethylsilyl (TMS) derivatives. The eff