Loss of fatty acid degradation by astrocytic mitochondria triggers neuroinflammation and neurodegeneration.

Autor: Mi Y; Center for Innovation in Brain Science, University of Arizona Health Sciences, Tucson, AZ, USA., Qi G; Center for Innovation in Brain Science, University of Arizona Health Sciences, Tucson, AZ, USA., Vitali F; Center for Innovation in Brain Science, University of Arizona Health Sciences, Tucson, AZ, USA.; Department of Neurology, College of Medicine Tucson, University of Arizona, Tucson, AZ, USA., Shang Y; Center for Innovation in Brain Science, University of Arizona Health Sciences, Tucson, AZ, USA., Raikes AC; Center for Innovation in Brain Science, University of Arizona Health Sciences, Tucson, AZ, USA., Wang T; Center for Innovation in Brain Science, University of Arizona Health Sciences, Tucson, AZ, USA.; Department of Neurology, College of Medicine Tucson, University of Arizona, Tucson, AZ, USA., Jin Y; Center of Translational Science, Florida International University, Port St. Lucie, FL, USA., Brinton RD; Center for Innovation in Brain Science, University of Arizona Health Sciences, Tucson, AZ, USA.; Department of Neurology, College of Medicine Tucson, University of Arizona, Tucson, AZ, USA.; Department of Pharmacology, College of Medicine Tucson, University of Arizona, Tucson, AZ, USA.; Graduate Interdisciplinary Program in Neuroscience, University of Arizona, Tucson, AZ, USA., Gu H; Center of Translational Science, Florida International University, Port St. Lucie, FL, USA., Yin F; Center for Innovation in Brain Science, University of Arizona Health Sciences, Tucson, AZ, USA. feiyin@arizona.edu.; Department of Pharmacology, College of Medicine Tucson, University of Arizona, Tucson, AZ, USA. feiyin@arizona.edu.; Graduate Interdisciplinary Program in Neuroscience, University of Arizona, Tucson, AZ, USA. feiyin@arizona.edu.

Publikováno v: Nature metabolism [Nat Metab] 2023 Mar; Vol. 5 (3), pp. 445-465. Date of Electronic Publication: 2023 Mar 23.

Contributions of sex and genotype to exploratory behavior differences in an aged humanized APOE mouse model of late-onset Alzheimer's disease.

Autor: McLean JW; Center for Innovation in Brain Science, University of Arizona, Tucson, Arizona 85721, USA.; Graduate Interdisciplinary Program in Neuroscience, University of Arizona, Tucson, Arizona 85721, USA., Bhattrai A; Center for Innovation in Brain Science, University of Arizona, Tucson, Arizona 85721, USA.; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona 85724, USA., Vitali F; Center for Innovation in Brain Science, University of Arizona, Tucson, Arizona 85721, USA., Raikes AC; Center for Innovation in Brain Science, University of Arizona, Tucson, Arizona 85721, USA., Wiegand JL; Center for Innovation in Brain Science, University of Arizona, Tucson, Arizona 85721, USA., Brinton RD; Center for Innovation in Brain Science, University of Arizona, Tucson, Arizona 85721, USA.; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona 85724, USA.

Publikováno v: Learning & memory (Cold Spring Harbor, N.Y.) [Learn Mem] 2022 Sep 02; Vol. 29 (9), pp. 321-331. Date of Electronic Publication: 2022 Sep 02 (Print Publication: 2022).

Exploratory imaging outcomes of a phase 1b/2a clinical trial of allopregnanolone as a regenerative therapeutic for Alzheimer's disease: Structural effects and functional connectivity outcomes.

Autor: Raikes AC; Center for Innovation in Brain Science University of Arizona Tucson Arizona USA., Hernandez GD; Center for Innovation in Brain Science University of Arizona Tucson Arizona USA., Matthews DC; Departments of Pharmacology and Neurology, College of Medicine ADM Diagnostics Northbrook Illinois USA., Lukic AS; Departments of Pharmacology and Neurology, College of Medicine ADM Diagnostics Northbrook Illinois USA., Law M; Department of Radiology Alfred Health Department of Neuroscience and Computer Systems Engineering Monash University Melbourne Australia., Shi Y; Stevens Neuroimaging and Informatics Institute Keck School of Medicine University of Southern California Los Angeles California USA., Schneider LS; Keck School of Medicine University of Southern California Los Angeles California USA., Brinton RD; Center for Innovation in Brain Science University of Arizona Tucson Arizona USA.

Publikováno v: Alzheimer's & dementia (New York, N. Y.) [Alzheimers Dement (N Y)] 2022 Mar 14; Vol. 8 (1), pp. e12258. Date of Electronic Publication: 2022 Mar 14 (Print Publication: 2022).

Exposure to Blue Wavelength Light Is Associated With Increases in Bidirectional Amygdala-DLPFC Connectivity at Rest.

Autor: Alkozei A; Social, Cognitive, and Affective Neuroscience Laboratory, Department of Psychiatry, University of Arizona, Tucson, AZ, United States., Dailey NS; Social, Cognitive, and Affective Neuroscience Laboratory, Department of Psychiatry, University of Arizona, Tucson, AZ, United States., Bajaj S; Multimodal Clinical Neuroimaging Laboratory (MCNL), Center for Neurobehavioral Research, Boys Town National Research Hospital, Boys Town, NE, United States., Vanuk JR; Social, Cognitive, and Affective Neuroscience Laboratory, Department of Psychiatry, University of Arizona, Tucson, AZ, United States., Raikes AC; Social, Cognitive, and Affective Neuroscience Laboratory, Department of Psychiatry, University of Arizona, Tucson, AZ, United States., Killgore WDS; Social, Cognitive, and Affective Neuroscience Laboratory, Department of Psychiatry, University of Arizona, Tucson, AZ, United States.

Publikováno v: Frontiers in neurology [Front Neurol] 2021 Mar 26; Vol. 12, pp. 625443. Date of Electronic Publication: 2021 Mar 26 (Print Publication: 2021).

Blue light exposure enhances neural efficiency of the task positive network during a cognitive interference task.

Autor: Killgore WDS; Social, Cognitive and Affective Neuroscience Lab., University of Arizona College of Medicine, United States. Electronic address: killgore@psychiatry.arizona.edu., Dailey NS; Social, Cognitive and Affective Neuroscience Lab., University of Arizona College of Medicine, United States., Raikes AC; Social, Cognitive and Affective Neuroscience Lab., University of Arizona College of Medicine, United States., Vanuk JR; Social, Cognitive and Affective Neuroscience Lab., University of Arizona College of Medicine, United States., Taylor E; Social, Cognitive and Affective Neuroscience Lab., University of Arizona College of Medicine, United States., Alkozei A; Social, Cognitive and Affective Neuroscience Lab., University of Arizona College of Medicine, United States.

Publikováno v: Neuroscience letters [Neurosci Lett] 2020 Sep 14; Vol. 735, pp. 135242. Date of Electronic Publication: 2020 Jul 08.