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Akademický článek

Continuous deep brain stimulation of the nucleus accumbens reduces food intake but does not affect body weight in mice fed a high-fat diet

Autor: Harold F. Hounchonou, Hui Tang, Raik Paulat, Andrea Kühn, Joachim Spranger, Christoph van Riesen, Lukas Maurer

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)

Abstract Obesity is an enormous health problem, and many patients do not respond to any of the available therapies. Deep brain stimulation (DBS) is currently investigated as a potential treatment for morbid obesity. In this study, we tested the hypot

Externí odkaz: https://doaj.org/article/ab9ccab50b7145ba8828f655cb04fa8f

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Experimental deep brain stimulation in rodent models of movement disorders

Autor: Heinz Endres, Cordula Matthies, Nikolaus Wenger, Chi Wang Ip, Christoph Harms, Susanne Knorr, Thomas Musacchio, Raik Paulat

Publikováno v: Experimental neurology. 348

Deep brain stimulation (DBS) is the preferred treatment for therapy-resistant movement disorders such as dystonia and Parkinson's disease (PD), mostly in advanced disease stages. Although DBS is already in clinical use for ~30 years and has improved

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa335563c035f4ef5d5e84ad55cb34b
https://pubmed.ncbi.nlm.nih.gov/34793784

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Development of an implantable microstimulation system for chronic DBS in rodents

Autor: Wassilios G. Meissner, Rudolf Morgenstern, Raik Paulat, Daniel Harnack, Andreas Kupsch

Publikováno v: EMBC

High frequency deep brain stimulation (DBS) of certain basal ganglia nuclei (e.g. subthalamic nucleus, STN) has emerged as a powerful neuromodulatory approach in the treatment of late stage Parkinson's disease patients. However, the underlying mechan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a10f3951e31aef2ce2e406730eb2d6d
https://pubmed.ncbi.nlm.nih.gov/22254395

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Continuous high-frequency stimulation in freely moving rats: development of an implantable microstimulation system

Autor: Raik Paulat, Wassilios G. Meissner, Christine Winter, Wolf-Dieter Müller, Rudolf Morgenstern, Andreas Kupsch, Daniel Harnack, Hannes Hilgenfeld

Publikováno v: Journal of neuroscience methods. 167(2)

High-frequency stimulation (HFS) of basal ganglia and thalamic nuclei is an established treatment for various movement disorders and has recently been extended to other neuro-psychiatric conditions. Numerous experimental studies in small laboratory a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d182c23a9cd5f50327e2474abf25666
https://pubmed.ncbi.nlm.nih.gov/17942159

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A cold-response index for the assessment of Raynaud's phenomenon

Autor: Ruth Pauli, Markus Eweleit, John Foerster, Gabriela Riemekasten, Margitta Worm, Raik Paulat, Esther Krautwald, Eyline Niederstrasser, Anja Kuerth

Publikováno v: Journal of dermatological science. 45(2)

Quantification of Raynaud's phenomenon (RP) is a prerequisite in the evaluation of novel therapeutic strategies. Fingertip rewarming in response to local cold provocation has been used in many studies but not been systematically validated. We have pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9659e5711ae101278b4c19ee2c3682c
https://pubmed.ncbi.nlm.nih.gov/17169532

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Akademický článek

Continuous deep brain stimulation of the nucleus accumbens reduces food intake but does not affect body weight in mice fed a high-fat diet.

Autor: Hounchonou, Harold F.^1,2,3 (AUTHOR), Tang, Hui^1,2 (AUTHOR), Paulat, Raik⁴ (AUTHOR), Kühn, Andrea⁴ (AUTHOR), Spranger, Joachim^1,2 (AUTHOR), van Riesen, Christoph^4,5 (AUTHOR), Maurer, Lukas^1,2 (AUTHOR) lukas.maurer@charite.de

Publikováno v: Scientific Reports. 11/2/2023, Vol. 13 Issue 1, p1-11. 11p.

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