Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Raihan K Uddin"'
Autor:
Raihan K Uddin, Shiva M Singh
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69768 (2013)
A number of gene expression microarray studies have been carried out in the past, which studied aging and age-associated spatial learning impairment (ASLI) in the hippocampus in animal models, with varying results. Data from such studies were never i
Externí odkaz:
https://doaj.org/article/899f3424688149aa83f030643334a175
Autor:
Shiva M. Singh, Raihan K. Uddin
Publikováno v:
Frontiers in Systems Neuroscience
Frontiers in Systems Neuroscience, Vol 11 (2017)
Frontiers in Systems Neuroscience, Vol 11 (2017)
As humans age many suffer from a decrease in normal brain functions including spatial learning impairments. This study aimed to better understand the molecular mechanisms in age-associated spatial learning impairment (ASLI). We used a mathematical mo
Autor:
Michelle Harrison, Shiva M. Singh, Morgan L. Kleiber, Raihan K. Uddin, Julie TreadwellJ. Treadwell
Publikováno v:
Genome. 50:877-897
Most familial behavioral phenotypes result from the complex interaction of multiple genes. Studies of such phenotypes involving human subjects are often inconclusive owing to complexity of causation and experimental limitations. Studies of animal mod
Autor:
Shiva M. Singh, Raihan K. Uddin
Publikováno v:
Brain Research. 1088:31-44
The physiological effects of alcohol are known to include drunkenness, toxicity, and addiction leading to alcohol-related health and societal problems. Some of these effects are mediated by regulation of expression of many genes involved in alcohol r
Publikováno v:
Biochemical Genetics. 40:395-410
Strains of mice that differ in voluntary alcohol consumption (VAC) are valuable models for the identification of genes involved in the complex etiology of alcohol effects and alcoholism. These mice offer a novel approach to the identification of stra
Autor:
Raihan K. Uddin, Shiva M. Singh
Publikováno v:
Addiction Medicine ISBN: 9781441903372
Metabolomics together with genomics and proteomics contribute towards a better understanding of biological processes including addiction through a modern integrative approach known as systems biology. The excessive economic and social cost of drug ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca6df1a1acf120c8718508f39ef6f8d3
https://doi.org/10.1007/978-1-4419-0338-9_12
https://doi.org/10.1007/978-1-4419-0338-9_12
Autor:
Raihan K. Uddin, Shiva M. Singh
Publikováno v:
The pharmacogenomics journal. 7(1)
Transcription factors (TFs) and their combinatorial control on cis-regulatory elements play critical role in the co-expression of genes. This affects the interaction of genes in the transcriptome and thus may affect signals that cascade through cellu
Autor:
Yang Zhang, Shiva M. Singh, Richard O'Reilly, Jay Rao, Victoria Mok Siu, Raihan K. Uddin, Yao Shan Fan
Publikováno v:
BMC Medical Genetics, Vol 7, Iss 1, p 18 (2006)
BMC Medical Genetics
Biology Publications
BMC Medical Genetics
Biology Publications
Background Chromosome 22q11.2 region is highly susceptible to rearrangement, specifically deletions that give rise to a variety of genomic disorders including velocardiofacial or DiGeorge syndrome. Individuals with this 22q11 microdeletion syndrome a
Publikováno v:
Alcoholism, clinical and experimental research. 30(1)
Background: Metallothioneins (MTs) are ubiquitously expressed intracellular proteins that bind heavy metals and are involved in cytoprotection against several types of stress agents including chemicals, hormones, and oxidants. We have previously repo
Publikováno v:
Neurochemical research. 30(9)
The search for genetic causes involved in alcohol dependence/response has been challenging. Understanding the mechanisms of action and interaction of the genes implicated in alcohol response is a key towards understanding the problem. Sixty-nine etha