Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Raichel M. Alex"'
Autor:
Yao Shun Chaung, Raichel M. Alex, Mahrshi Jani, Donald E. Watenpaugh, Radana Vilimkova Kahankova, Scott A. Sands, Khosrow Behbehani
Publikováno v:
Sleep Disorders, Vol 2023 (2023)
Obstructive sleep apnea (OSA) pathologically stresses the cardiovascular system. Apneic events cause significant oscillatory surges in nocturnal blood pressure (BP). Trajectories of these surges vary widely. This variability challenges the quantifica
Externí odkaz:
https://doaj.org/article/d3df86336d614981bb3063245073104d
Autor:
Scott A. Sands, Raichel M. Alex, Dwayne Mann, Daniel Vena, Philip I. Terrill, Laura K. Gell, Andrey Zinchuk, Tamar Sofer, Sanjay R. Patel, Luigi Taranto-Montemurro, Ali Azarbarzin, Michael Rueschman, David P. White, Andrew Wellman, Susan Redline
Publikováno v:
Annals of the American Thoracic Society. 20:440-449
Sleep apnea is the manifestation of key "endotypic traits" including greater pharyngeal collapsibility, reduced dilator muscle compensation and elevated chemoreflex loop gain.We investigate how endotypic traits vary with obesity, age, sex, and race/e
Autor:
Eysteinn Finnsson, Eydís Arnardóttir, Wan-Ju Cheng, Raichel M. Alex, Þóra B. Sigmarsdóttir, Snorri Helgason, Liang-Wen Hang, Jón S. Ágústsson, Andrew Wellman, Scott A. Sands
Publikováno v:
Frontiers in Sleep. 2
Obstructive sleep apnea (OSA) is a common disorder characterized by recurrent upper airway obstruction during sleep. Despite the availability of continuous positive airway pressure (CPAP) as the gold standard treatment, it is not well tolerated by al
Autor:
Jordan D Bird, Scott A. Sands, Raichel M Alex, Conan L.H. Shing, Brooke M Shafer, Nicholas G Jendzjowsky, Richard J.A. Wilson, Trevor A Day, Glen E Foster
Publikováno v:
Annals of the American Thoracic Society.
Autor:
Magdy Younes, Luigi Taranto-Montemurro, Daniel Vena, Raichel M. Alex, Sang-Wook Kim, Ali Azarbarzin, Andrew Wellman, Scott A. Sands, Tamar Sofer, Susan Redline, David P. White, Daniel J. Gottlieb
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 203:1546-1555
Rationale: Randomized controlled trials have been unable to detect a cardiovascular benefit of continuous positive airway pressure in unselected patients with obstructive sleep apnea (OSA). We hypo...
Autor:
Raichel M Alex, Tamar Sofer, Ali Azarbarzin, Daniel Vena, Laura K Gell, Andrew Wellman, David P White, Susan Redline, Scott A Sands
Publikováno v:
Sleep. 45(9)
Study Objectives Obstructive sleep apnea (OSA) is characterized by multiple “endotypic traits,” including pharyngeal collapsibility, muscle compensation, loop gain, and arousal threshold. Here, we examined (1) within-night repeatability, (2) long
Autor:
Laura K Gell, Daniel Vena, Raichel M Alex, Ali Azarbarzin, Nicole Calianese, Lauren B Hess, Luigi Taranto-Montemurro, David P White, Andrew Wellman, Scott A Sands
Publikováno v:
Thorax. 77(7)
BackgroundIn the classic model of obstructive sleep apnoea (OSA), respiratory events occur with sleep-related dilator muscle hypotonia, precipitating increased neural ventilatory ‘drive’. By contrast, a drive-dependent model has been proposed, wh
Autor:
Gino S. Panza, Huzaifa Hakim, M. Safwan Badr, Jason H. Mateika, Bradley A. Edwards, Scott A. Sands, Raichel M. Alex
Publikováno v:
The Journal of Physiology. 597:3697-3711
KEY POINTS Repeated daily mild intermittent hypoxia has been endorsed as a therapy to promote the recovery of respiratory and limb motor dysfunction. One possible side-effect of this therapy is an increase in apnoeic event number and duration, which
Publikováno v:
Computers in Biology and Medicine. 108:196-199
Publikováno v:
Respiratory Physiology & Neurobiology. 256:58-66
The following review explores the effect that intermittent or sustained hypercapnia coupled to intermittent hypoxia has on respiratory plasticity. The review explores published work which suggests that intermittent hypercapnia leads to long-term depr