Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Rahwa A Woldeyesus"'
Autor:
Yi-Je Chen, James W. Chan, Rafael Shimkunas, Samir Awasthi, Trevor Landas, Brittani Wood, Nipavan Chiamvimonvat, Dennis L Matthews, Ye Chen-Izu, Zhong Jian, Deborah K. Lieu, Rahwa A Woldeyesus, Ziliang Mao, Aaron Lerner, Julie Bossuyt, Kit S. Lam, Leighton T. Izu
Publikováno v:
SPIE Proceedings.
The objective of this study was to develop a method for simultaneously measuring the calcium and contraction dynamics of single, live cardiomyocytes at high spatial resolutions. Such measurements are important to investigate local calcium release and
Autor:
Nipavan Chiamvimonvat, Zhong Jian, Brent M. Wood, Ziliang Mao, Dennis L Matthews, Deborah K. Lieu, Julie Bossuyt, Aaron Lerner, Leighton T. Izu, Rahwa A Woldeyesus, Kit S. Lam, Samir Awasthi, Yi-Je Chen, Ye Chen-Izu, Rafael Shimkunas, James W. Chan, Trevor Landas
Publikováno v:
Circulation research, vol 118, iss 2
Rationale: Cardiac myocyte contraction is caused by Ca 2+ binding to troponin C, which triggers the cross-bridge power stroke and myofilament sliding in sarcomeres. Synchronized Ca 2+ release causes whole cell contraction and is readily observable wi