Výsledky vyhledávání - "Rahul Ravichandran"

Akademický článek

Issues that affected the mental health of children in India during COVID-19 and efforts taken by the Indian Government to address them

Autor: Latika Chugh, Rahul Ravichandran

Publikováno v: Global Journal of Medicine and Public Health, Vol 11, Iss 4 (2024)

The COVID-19 pandemic resulted in the world's strictest lockdown, that had a tremendous influence on the mental health of all people worldwide, especially with children being a vulnerable group prone to negative consequences. This commentary deals wi

Externí odkaz: https://doaj.org/article/1ff958c09e284db08f8498da3ce601a0

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Akademický článek

Carbonic anhydrase activation profile of indole-based derivatives

Autor: Elisabetta Barresi, Rahul Ravichandran, Lorenzo Germelli, Andrea Angeli, Emma Baglini, Silvia Salerno, Anna Maria Marini, Barbara Costa, Eleonora Da Pozzo, Claudia Martini, Federico Da Settimo, Claudiu Supuran, Sandro Cosconati, Sabrina Taliani

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1783-1797 (2021)

Carbonic Anhydrase Activators (CAAs) could represent a novel approach for the treatment of Alzheimer’s disease, ageing, and other conditions that require remedial achievement of spatial learning and memory therapy. Within a research project aimed a

Externí odkaz: https://doaj.org/article/61803acb569c43b59486f5dce895777a

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Akademický článek

Tetrahydroquinazole-based secondary sulphonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IV, and IX, and computational studies

Autor: Emma Baglini, Rahul Ravichandran, Emanuela Berrino, Silvia Salerno, Elisabetta Barresi, Anna Maria Marini, Monica Viviano, Sabrina Castellano, Federico Da Settimo, Claudiu T. Supuran, Sandro Cosconati, Sabrina Taliani

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1874-1883 (2021)

A library of variously decorated N-phenyl secondary sulphonamides featuring the bicyclic tetrahydroquinazole scaffold was synthesised and biologically evaluated for their inhibitory activity against human carbonic anhydrase (hCA) I, II, IV, and IX. O

Externí odkaz: https://doaj.org/article/88031813ab9443118c310ad8a0e3ccdb

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Akademický článek

Development of Reduced Peptide Bond Pseudopeptide Michael Acceptors for the Treatment of Human African Trypanosomiasis

Autor: Santo Previti, Roberta Ettari, Carla Di Chio, Rahul Ravichandran, Marta Bogacz, Ute A. Hellmich, Tanja Schirmeister, Sandro Cosconati, Maria Zappalà

Publikováno v: Molecules, Vol 27, Iss 12, p 3765 (2022)

Human African Trypanosomiasis (HAT) is an endemic protozoan disease widespread in the sub-Saharan region that is caused by T. b. gambiense and T. b. rhodesiense. The development of molecules targeting rhodesain, the main cysteine protease of T. b. rh

Externí odkaz: https://doaj.org/article/5873f4bdecaa4d6e87e4e4cfc50782cc

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Akademický článek

Genetics of PCOS: A systematic bioinformatics approach to unveil the proteins responsible for PCOS

Autor: Pritam Kumar Panda, Riya Rane, Rahul Ravichandran, Shrinkhla Singh, Hetalkumar Panchal

Publikováno v: Genomics Data, Vol 8, Iss C, Pp 52-60 (2016)

Polycystic ovary syndrome (PCOS) is a hormonal imbalance in women, which causes problems during menstrual cycle and in pregnancy that sometimes results in fatality. Though the genetics of PCOS is not fully understood, early diagnosis and treatment ca

Externí odkaz: https://doaj.org/article/f94c8ccaa6bd4741af870d47e52aea74

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Comparative Analysis of Groundwater Quality Index for Bhavani River Basin Using Remote Sensing and Statistical Analysis

Autor: Rahul Ravichandran, Raviraj Ayyavoo, Lalitha Rajangam, Nagarajan Madasamy, Basker Murugaiyan, Sumathi Shanmugam

Publikováno v: Jordan Journal of Civil Engineering. 17:58-70

This research was conducted to examine the drinking (WQI1) and irrigation (WQI2) water quality for the Bhavani river basin using statistical methodologies. The study area geographically covers up to 4207 km2. For evaluating the Water Quality Index (W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3adaa1fb3d7f09f1842705b761fc86bb
https://doi.org/10.14525/jjce.v17i1.06

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Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain

Autor: Santo Previti, Roberta Ettari, Elsa Calcaterra, Carla Di Chio, Rahul Ravichandran, Collin Zimmer, Stefan Hammerschmidt, Annika Wagner, Marta Bogacz, Sandro Cosconati, Tanja Schirmeister, Maria Zappalà

Publikováno v: ACS medicinal chemistry letters. 13(7)

Human African Trypanosomiasis (HAT) is a neglected tropical disease widespread in sub-Saharan Africa. Rhodesain, a cysteine protease of Trypanosoma brucei rhodesiense, has been identified as a valid target for the development of anti-HAT agents. Here

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7271d21b0301d852592b9187cb8dd482
https://pubmed.ncbi.nlm.nih.gov/35859868

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Carbonic anhydrase activation profile of indole-based derivatives

Autor: Federico Da Settimo, Sandro Cosconati, Claudia Martini, Eleonora Da Pozzo, Claudiu T. Supuran, Andrea Angeli, Elisabetta Barresi, Barbara Costa, Lorenzo Germelli, Rahul Ravichandran, Emma Baglini, Silvia Salerno, Sabrina Taliani, Anna Maria Marini

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1783-1797 (2021)
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ab3f3c620e14b64aa7da5388937e37
https://doaj.org/article/61803acb569c43b59486f5dce895777a

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