Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Rahul Palchaudhuri"'
Autor:
Naoya Uchida, Ulana Stasula, Selami Demirci, Paula Germino-Watnick, Malikiya Hinds, Anh Le, Rebecca Chu, Alexander Berg, Xiong Liu, Ling Su, Xiaolin Wu, Allen E. Krouse, N. Seth Linde, Aylin Bonifacino, So Gun Hong, Cynthia E. Dunbar, Leanne Lanieri, Anjali Bhat, Rahul Palchaudhuri, Bindu Bennet, Megan Hoban, Kirk Bertelsen, Lisa M. Olson, Robert E. Donahue, John F. Tisdale
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Hematopoietic stem cell (HSC) gene therapy has curative potential; however, its use is limited by the morbidity and mortality associated with current chemotherapy-based conditioning. Targeted conditioning using antibody-drug conjugates (ADC)
Externí odkaz:
https://doaj.org/article/da5777a8fdb54d1094c35c66359052e6
Autor:
Meera A. Srikanthan, Olivier Humbert, Kevin G. Haworth, Christina Ironside, Yogendra S. Rajawat, Bruce R. Blazar, Rahul Palchaudhuri, Anthony E. Boitano, Michael P. Cooke, David T. Scadden, Hans-Peter Kiem
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 455-464 (2020)
Conditioning chemotherapy is used to deplete hematopoietic stem cells in the recipient’s marrow, facilitating donor cell engraftment. Although effective, a major issue with chemotherapy is the systemic genotoxicity that increases the risk for secon
Externí odkaz:
https://doaj.org/article/c5914d1b216b478194b953206195ad04
Autor:
Agnieszka Czechowicz, Rahul Palchaudhuri, Amelia Scheck, Yu Hu, Jonathan Hoggatt, Borja Saez, Wendy W. Pang, Michael K. Mansour, Tiffany A. Tate, Yan Yi Chan, Emily Walck, Gerlinde Wernig, Judith A. Shizuru, Florian Winau, David T. Scadden, Derrick J. Rossi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Hematopoietic stem cell (HSC) transplantation is a desirable treatment for many non-malignant and malignant diseases, but its use requires preconditioning of recipients with irradiation or chemotherapy that often induces high toxicity. Here the autho
Externí odkaz:
https://doaj.org/article/9ffac621975f4bccb6eaeafd10b5ba55
Autor:
Rahul Palchaudhuri, Michael J. Lambrecht, Rachel C. Botham, Kathryn C. Partlow, Tjakko J. van Ham, Karson S. Putt, Laurie T. Nguyen, Seok-Ho Kim, Randall T. Peterson, Timothy M. Fan, Paul J. Hergenrother
Publikováno v:
Cell Reports, Vol 13, Iss 9, Pp 2027-2036 (2015)
Apoptosis is generally believed to be a process that requires several hours, in contrast to non-programmed forms of cell death that can occur in minutes. Our findings challenge the time-consuming nature of apoptosis as we describe the discovery and c
Externí odkaz:
https://doaj.org/article/530d352d31b840048247d0aebf599f18
Autor:
Rahul Palchaudhuri, Selami Demirci, Leanne Lanieri, Sharon L. Hyzy, Anjali Bhat, Tahirih L. Lamothe, Katelyn Hammond, Tiffany Tate, Zhuyan Guo, Eric Cheah, Xin Qiao, Jing Zeng, Stacy A. Maitland, Bindu Bennet, Kirk Bertelsen, Robert E. Donahue, Scot A. Wolfe, Daniel E. Bauer, John F. Tisdale, Lisa M. Olson
Publikováno v:
Transplantation and Cellular Therapy. 29:S165-S166
Publikováno v:
Blood. 140:10227-10228
Autor:
Anthony E. Boitano, Rahul Palchaudhuri, Hans-Peter Kiem, David T. Scadden, Meera A. Srikanthan, Christina Ironside, Olivier Humbert, Kevin G. Haworth, Bruce R. Blazar, Yogendra S. Rajawat, Michael P. Cooke
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 455-464 (2020)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Conditioning chemotherapy is used to deplete hematopoietic stem cells in the recipient’s marrow, facilitating donor cell engraftment. Although effective, a major issue with chemotherapy is the systemic genotoxicity that increases the risk for secon
Autor:
Asim Saha, Sharon Hyzy, Tahirih Lamothe, Katelyn Hammond, Nicholas Clark, Leanne Lanieri, Prashant Bhattarai, Rahul Palchaudhuri, Geoffrey O. Gillard, Jennifer Proctor, Megan J. Riddle, Angela Panoskaltsis-Mortari, Margaret L. MacMillan, John E. Wagner, Hans-Peter Kiem, Lisa M. Olson, Bruce R. Blazar
Publikováno v:
Blood
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative treatment of patients with nonmalignant or malignant blood disorders. Its success has been limited by graft-versus-host disease (GVHD). Current systemic nontarge
Autor:
Tiffany A. Tate, David T. Scadden, Emily Walck, Judith A. Shizuru, Rahul Palchaudhuri, Yu Hu, Jonathan Hoggatt, Wendy W. Pang, Amelia Scheck, Yan-Yi Chan, Michael K. Mansour, Borja Saez, Agnieszka Czechowicz, Derrick J. Rossi, Florian Winau, Gerlinde Wernig
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Nature Communications
Hematopoietic stem cell transplantation (HSCT) is a curative therapy for blood and immune diseases with potential for many settings beyond current standard-of-care. Broad HSCT application is currently precluded largely due to morbidity and mortality
Autor:
Rahul Palchaudhuri, Naoya Uchida, Ulana Stasula, Malikiya Hinds, Paula Germino-Watnick, Allen E Krouse, Nathaniel Linde, Aylin Bonifacino, Kellie Latimer, Prashant raj Bhattarai, Nicholas C Yoder, Qing Li, Kirk Bertelsen, Lisa M Olson, Robert E. Donahue, John F. Tisdale
Publikováno v:
Transplantation and Cellular Therapy. 28:S238