Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Rahul Nahire"'
Publikováno v:
International Journal of Genomics, Vol 2016 (2016)
Identification of pathogenic germline mutations by next generation sequencing is a widely accepted tool for predicting the risk of hereditary cancer development. Blood is the most common source of DNA for such tests. However, blood as a sample type h
Externí odkaz:
https://doaj.org/article/fb90a477f64e4bb883cbbd6016042585
Publikováno v:
International Journal of Genomics
International Journal of Genomics, Vol 2016 (2016)
International Journal of Genomics, Vol 2016 (2016)
Identification of pathogenic germline mutations by next generation sequencing is a widely accepted tool for predicting the risk of hereditary cancer development. Blood is the most common source of DNA for such tests. However, blood as a sample type h
Autor:
Kara N. Gange, Estelle Leclerc, Avinash H. Ambre, Kalpana S. Katti, Sanku Mallik, Varsha Meghnani, Kausik Sarkar, Rupa Patel, D. K. Srivastava, Rayat Hossain, Rahul Nahire, Shirshendu Paul
Publikováno v:
Molecular Pharmaceutics
Liposomes are representative lipid nanoparticles widely used for delivering anticancer drugs, DNA fragments, or siRNA to cancer cells. Upon targeting, various internal and external triggers have been used to increase the rate for contents release fro
Publikováno v:
Acta Chromatographica. 24:419-432
Summary A simple, rapid, precise, and accurate, stability-indicating reversed phase high performance liquid chromatographic method was developed and validated for simultaneous determination of metformin HCl and repaglinide. The chromatographic separa
Autor:
Wallace W. Muhonen, Rahul Nahire, Sanku Mallik, Kausik Sarkar, Raushan K. Singh, Kara N. Gange, Michael D. Scott, D. K. Srivastava, John B. Shabb, Shirshendu Paul
Publikováno v:
Molecular Pharmaceutics. 9:2554-2564
The extracellular enzyme matrix metalloproteinase-9 (MMP-9) is overexpressed in atherosclerotic plaques and in metastatic cancers. The enzyme is responsible for rupture of the plaques and for the invasion and metastasis of a large number of cancers.
Autor:
Sathish K.R. Padi, Wallace W. Muhonen, John B. Shabb, Katie M. Reindl, Bin Guo, Kalpana S. Katti, D. K. Shrivastava, Manas K. Haldar, Preeya Katti, Avinash H. Ambre, Rahul Nahire, Pawel P. Borowicz, Prajakta Kulkarni, Sanku Mallik, Raushan K. Singh
Publikováno v:
Molecular Pharmaceutics
Significant differences in biochemical parameters between normal and tumor tissues offer an opportunity to chemically design drug carriers which respond to these changes and deliver the drugs at the desired site. For example, overexpression of the ma
Autor:
Rahul Nahire, Shirshendu Paul, Buddhadev Layek, Kausik Sarkar, Kara N. Gange, Jagdish Singh, Sanku Mallik, Kalpana S. Katti, Varsha Meghnani, Avinash H. Ambre, Manas K. Haldar
Although liposomes are widely used as carriers of drugs and imaging agents, they suffer from a lack of stability and the slow release of the encapsulated contents at the targeted site. Polymersomes (vesicles of amphiphilic polymers) are considerably
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd03dbd08768af6e92a52f64bccf2f2
https://europepmc.org/articles/PMC4059508/
https://europepmc.org/articles/PMC4059508/
Micron- to nanometer-sized ultrasound agents, like encapsulated microbubbles and echogenic liposomes, are being developed for diagnostic imaging and ultrasound mediated drug/gene delivery. This review provides an overview of the current state of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21caeb3d244db531eeb582d6eee6ef57
https://europepmc.org/articles/PMC4470369/
https://europepmc.org/articles/PMC4470369/
Autor:
Sanku Mallik, Kalpana S. Katti, Rahul Nahire, Manas K. Haldar, Kausik Sarkar, Kara N. Gange, Avinash H. Ambre, D. K. Srivastava, Anaas Mergoum, Shirshendu Paul
Publikováno v:
Biomacromolecules. 14(3)
Although lipid nanoparticles are promising drug delivery vehicles, passive release of encapsulated contents at the target site is often slow. Herein, we report contents release from targeted, polymer coated, echogenic lipid nanoparticles in the cell
Autor:
Kalpana S. Katti, Avinash H. Ambre, Daniel Russakow, Rahul Nahire, Kausik Sarkar, Sanku Mallik, Tapas Nandy, Shirshendu Paul
Publikováno v:
Ultrasonics. 52(7)
Echogenic liposomes (ELIP) are an excellent candidate for concurrent imaging and drug delivery applications. They combine the advantages of liposomes-biocompatibility and ability to encapsulate both hydrophobic and hydrophilic drugs-with strong refle