Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Rahul Kuver"'
Autor:
George N. Ioannou, Charles S. Landis, Ga‐Young Jin, W. Geoffrey Haigh, Geoffrey C. Farrell, Rahul Kuver, Sum P. Lee, Christopher Savard
Publikováno v:
Hepatology Communications, Vol 3, Iss 6, Pp 776-791 (2019)
It is unclear what drives the development of fibrosing nonalcoholic steatohepatitis (NASH). We aimed to determine whether cholesterol crystallization within hepatocyte lipid droplets (LDs) distinguishes patients with fibrosing NASH from patients with
Externí odkaz:
https://doaj.org/article/8c4438f8f6c6437b998d19525840e1a2
Publikováno v:
F1000Research, Vol 5 (2016)
A variety of diseases are included under the umbrella term ‘cholangitis’, including hepatobiliary diseases with an autoimmune pathogenesis (such as primary sclerosing cholangitis, primary biliary cholangitis, and IgG4-associated sclerosing cholan
Externí odkaz:
https://doaj.org/article/8f60555a15be4cf69a40f2644c598fe5
Autor:
Puangrat Yongvanit, W. Geoffrey Haigh, Anchalee Techasen, Apinya Jusakul, Watcharin Loilome, Christopher E. Savard, George N. Ioannou, Nisana Namwat, Rahul Kuver
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 138:368-375
The oxysterols cholestan-3β, 5α, 6β-triol (Triol) and 3-keto-cholest-4-ene (3K4) are increased in Opisthorchis viverrini-associated hamster cholangiocarcinoma and induce DNA damage and apoptosis via a mitochondria-dependent mechanism in MMNK-1 hum
Autor:
Rahul Kuver
Publikováno v:
Clinical Lipidology. 7:537-548
Oxysterols are oxidized species of cholesterol that are derived from exogenous (e.g. dietary) and endogenous (in vivo) sources. Oxysterols play critical roles in normal physiologic functions as well as in pathophysiologic processes in a variety of or
Autor:
Rahul Kuver
Publikováno v:
Journal of Gastroenterology and Hepatology. 25:1020-1023
Publikováno v:
The American Journal of Pathology. 174:842-853
We tested the hypothesis that well-differentiated gallbladder epithelial cells (GBECs) are capable of engrafting and surviving in murine liver and acquire phenotypic characteristics of hepatocytes. GBECs isolated from transgenic mice that constitutiv
Publikováno v:
Journal of Surgical Research. 141:183-191
The cellular and molecular mechanisms of fibrogenesis in the extrahepatic biliary epithelium are not known. Transforming growth factor-beta1 (TGF-beta1) is a cytokine implicated in signaling pathways that mediate collagen formation. An observation th
Autor:
Sum P. Lee, Rahul Kuver
Publikováno v:
New England Journal of Medicine. 354:1848-1851
Autor:
Rahul Kuver
Publikováno v:
Journal of Surgical Research. 182:207-209
Autor:
Rahul Kuver, Sum P. Lee
Publikováno v:
Biochemical and Biophysical Research Communications. 314:330-334
Because hypersecretion of gallbladder (GB) mucus occurs in gallstone formation and because binding of Ca(2+) to biliary lipids only accounts for 50% of the total Ca(2+) in GB bile, we investigated the binding of Ca(2+) to human biliary mucin. Biliary