Výsledky vyhledávání - "Rahul K. Das"

Abstract 4400: Machine learning (ML) on real-world data (RWD) of front-line (1L) metastatic castration resistance prostate cancer (mCRPC) patients for dynamic prediction of time to tx discontinuation (TTD)

Autor: Prerna Jain, Deep K. Hathi, Hossein Honarvar, Rahul K. Das

Publikováno v: Cancer Research. 83:4400-4400

Background: Abiraterone (abi) and enzalutamide (enza) are two novel androgen therapies (NAT) for 1L treatment (tx) for mCRPC. As there is no head-to-head randomized controlled clinical trial (RCT) between Abi and Enza, predicting 1L comparative effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::951a00f1d82cddf4fd8ab9158bf95dae
https://doi.org/10.1158/1538-7445.am2023-4400

Zobrazit plný text záznamu

Abstract 851: Machine learning (ML) model for prediction of pneumonitis using real-world data (RWD) on immune checkpoint inhibitor (ICI)-treated advanced non-small cell lung cancer (aNSCLC)

Autor: Deep K. Hathi, Heather Hall, Judith Mueller, Mona H. Cai, Yangyang Liu, Alexander Liede, Rahul K. Das

Publikováno v: Cancer Research. 83:851-851

Background: Immune-related pneumonitis (IRP) is a rare adverse event (AE) associated with ICIs that may result in treatment interruption or death if not managed properly. IRP prediction is critical to identify at-risk patients and estimate background

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ead32290d41ea3f60c0ec70d7bc0f5df
https://doi.org/10.1158/1538-7445.am2023-851

Zobrazit plný text záznamu

APOBEC mutagenesis and selection for NFE2L2 contribute to the origin of lung squamous-cell carcinoma

Autor: Vincent L. Cannataro, Shalley Kudalkar, Krishna Dasari, Stephen G. Gaffney, Heather M. Lazowski, Laura K. Jackson, Isil Yildiz, Rahul K. Das, Bonnie E. Gould Rothberg, Karen S. Anderson, Jeffrey P. Townsend

Publikováno v: Lung cancer (Amsterdam, Netherlands). 171

Lung squamous-cell carcinoma originates as a consequence of oncogenic molecular variants arising from diverse mutagenic processes such as tobacco, defective homologous recombination, aging, and cytidine deamination by APOBEC proteins. Only some of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17cb2bd7dc0dfa5ba87f4bbfb17fd3d
https://pubmed.ncbi.nlm.nih.gov/35872531

Zobrazit plný text záznamu

N-Doped Carbon Quantum Dot (NCQD)-Deposited Carbon Capsules for Synergistic Fluorescence Imaging and Photothermal Therapy of Oral Cancer

Autor: Rahul K. Das, Sasmita Mohapatra, Snigdharani Panda, Sujit K. Bhutia, Chandra Sekhar Bhol

Publikováno v: Langmuir. 35:15320-15329

Use of nanomaterials blessed with both therapeutic and diagnostic properties is a proficient strategy in the treatment of cancer in its early stage. In this context, our paper reports the synthesis of uniform size N-rich mesoporous carbon nanospheres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd3bb6b37da4c3acec076bf7290d112
https://doi.org/10.1021/acs.langmuir.9b03001

Zobrazit plný text záznamu

Ion Mobility Mass Spectrometry Uncovers the Impact of the Patterning of Oppositely Charged Residues on the Conformational Distributions of Intrinsically Disordered Proteins

Autor: Perdita E. Barran, Rohit V. Pappu, Lukasz G. Migas, Rahul K. Das, Rebecca Beveridge, Richard W. Kriwacki

Publikováno v: Journal of the American Chemical Society. 141:4908-4918

[Image: see text] The global dimensions and amplitudes of conformational fluctuations of intrinsically disordered proteins are governed, in part, by the linear segregation versus clustering of oppositely charged residues within the primary sequence.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d993d11cde94099d731da1d52f62ddd
https://doi.org/10.1021/jacs.8b13483

Zobrazit plný text záznamu

Machine learning modeling of real-world primary resistance and hyperprogression in immune checkpoint inhibitor (ICI) treated advanced non-small cell lung cancer (aNSCLC) patients

Autor: Rahul K Das, Deep K Hathi

Publikováno v: Journal of Clinical Oncology. 40:e21127-e21127

e21127 Background: Many ICI-eligible patients display primary resistance (10-res), with some experiencing hyperprogressive disease (HPD). Machine learning (ML) on real-world data (RWD) can improve our clinical and mechanistic understanding related to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aad0c23df9c3128f7db4dc8b96c8eba4
https://doi.org/10.1200/jco.2022.40.16_suppl.e21127

Zobrazit plný text záznamu

Rapid 'turn-on' detection of atrazine using highly luminescent N-doped carbon quantum dot

Autor: Sasmita Mohapatra, Rahul K. Das, Mihir K. Bera

Publikováno v: Sensors and Actuators B: Chemical. 263:459-468

Nitrogen doped carbon quantum dot based highly selective luminescent probe has been designed for the detection of herbicide atrazine. Nitrogen doped carbon quantum dot with PLQY 28% has been prepared from hydrothermal treatment of orthophenylene diam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e0cc0e3ff4a62bf49a5d93276f7b6e3
https://doi.org/10.1016/j.snb.2018.02.155

Zobrazit plný text záznamu

Highly luminescent, heteroatom-doped carbon quantum dots for ultrasensitive sensing of glucosamine and targeted imaging of liver cancer cells

Autor: Rahul K. Das, Sasmita Mohapatra

Publikováno v: J. Mater. Chem. B. 5:2190-2197

A novel fluorescent boronate nanoprobe has been synthesized by judiciously doping boron, nitrogen, and sulphur in carbon quantum dots (BNSCQD). Specifically, the synergistic presence of nitrogen and sulphur along with boronic acid provides excellent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e81da42832acf879fa0d446f322d0b4
https://doi.org/10.1039/c6tb03141b

Zobrazit plný text záznamu

CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins

Autor: Rahul K. Das, Alex S. Holehouse, Mary O.G. Richardson, James N. Ahad, Rohit V. Pappu

Publikováno v: Biophysical Journal. 112:16-21

Intrinsically disordered proteins and regions (IDPs) represent a large class of proteins that are defined by conformational heterogeneity and lack of persistent tertiary/secondary structure. IDPs play important roles in a range of biological function

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7126e3f25156eb26ee1847d511b125a
https://doi.org/10.1016/j.bpj.2016.11.3200

Zobrazit plný text záznamu

Enhanced Photodegradation of Organic Pollutants by Carbon Quantum Dot (CQD) Deposited Fe3O4@mTiO2 Nano-Pom-Pom Balls

Autor: Sasmita Mohapatra, Rahul K. Das, Jyoti Prakash Kar

Publikováno v: Industrial & Engineering Chemistry Research. 55:5902-5910

Highly water dispersible, superparamagnetic carbon quantum dot (CQD) deposited Fe3O4@mTiO2 pom-pom balls have been prepared by a simple hydrothermal method. The effective deposition of carbon dots expands the light absorption of mTiO2 from the UV to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0c6787c258c7d3dfd91546bf680be91
https://doi.org/10.1021/acs.iecr.6b00792

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání