Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Rahul K Suryawanshi"'
Autor:
Taha Y Taha, Rahul K Suryawanshi, Irene P Chen, Galen J Correy, Maria McCavitt-Malvido, Patrick C O'Leary, Manasi P Jogalekar, Morgan E Diolaiti, Gabriella R Kimmerly, Chia-Lin Tsou, Ronnie Gascon, Mauricio Montano, Luis Martinez-Sobrido, Nevan J Krogan, Alan Ashworth, James S Fraser, Melanie Ott
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1011614 (2023)
Despite unprecedented efforts, our therapeutic arsenal against SARS-CoV-2 remains limited. The conserved macrodomain 1 (Mac1) in NSP3 is an enzyme exhibiting ADP-ribosylhydrolase activity and a possible drug target. To determine the role of Mac1 cata
Externí odkaz:
https://doaj.org/article/389ee82ba53647589bf5956389b4ea8e
Autor:
Chandrashekhar D Patil, Hemant P Borase, Rahul B Salunkhe, Rahul K Suryawanshi, Chandrakant P Narkhade, Bipinchandra K Salunke, Satish V Patil
Publikováno v:
Journal of Arthropod-Borne Diseases, Vol 8, Iss 1 (2014)
Background: We aimed to extract the ingredients from leaves of Gossypium hirsutum (Bt cotton) using different solvents and evaluate for potential use to control different larval stages of mosquito species, Aedes aegypti and Anopheles stephensi. Metho
Externí odkaz:
https://doaj.org/article/ae9f8bb7918349109043d42e37e1612c
Autor:
Rahul K. Suryawanshi, Chandrashekhar D. Patil, Alex Agelidis, Raghuram Koganti, Joshua M. Ames, Lulia Koujah, Tejabhiram Yadavalli, Krishnaraju Madavaraju, Lisa M. Shantz, Deepak Shukla
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The immune response to herpes simplex virus is essential in limiting immunopathology during infection, however factors linked to neuroprotection are currently unclear. Here the authors implicate mTORC2 in the host response to viral infection and link
Externí odkaz:
https://doaj.org/article/27f4f68e4f724618b102cf6fe1166fed
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Herpes simplex virus type-1 (HSV-1) infections are known to alter the host metabolism for efficient propagation in vitro. However, in vivo metabolic perturbations upon prolonged HSV-1 infection remain poorly understood. We used high-resoluti
Externí odkaz:
https://doaj.org/article/3710d6cc1a814be395f6900a572b1ee7
Autor:
Alex Agelidis, Benjamin A. Turturice, Rahul K. Suryawanshi, Tejabhiram Yadavalli, Dinesh Jaishankar, Joshua Ames, James Hopkins, Lulia Koujah, Chandrashekhar D. Patil, Satvik R. Hadigal, Evan J. Kyzar, Anaamika Campeau, Jacob M. Wozniak, David J. Gonzalez, Israel Vlodavsky, Jin-ping Li, David L. Perkins, Patricia W. Finn, Deepak Shukla
Publikováno v:
JCI Insight, Vol 6, Iss 7 (2021)
The drive to withstand environmental stresses and defend against invasion is a universal trait extant in all forms of life. While numerous canonical signaling cascades have been characterized in detail, it remains unclear how these pathways interface
Externí odkaz:
https://doaj.org/article/2ffdf956e9364785bc5fbcaa308dd5a9
Autor:
Alex Agelidis, Rahul K. Suryawanshi, Chandrashekhar D. Patil, Anaamika Campeau, David J. Gonzalez, Deepak Shukla
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102242- (2021)
Summary: Balance between cell proliferation and elimination is critical in handling threats both exogenous and of internal dysfunction. Recent work has implicated a conserved but poorly understood endoglycosidase heparanase (HPSE) in the restriction
Externí odkaz:
https://doaj.org/article/d6de59674eed41b6af36ffc3548641d6
Autor:
Rahul K. Suryawanshi, Chandrashekhar D. Patil, Raghuram Koganti, Sudhanshu Kumar Singh, Joshua M. Ames, Deepak Shukla
Publikováno v:
Pathogens, Vol 10, Iss 7, p 803 (2021)
A novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic. While the world is striving for a treatment modality against SARS-CoV-2, our understanding about the virus entry mechanisms may help to design entry in
Externí odkaz:
https://doaj.org/article/6df489a65d924cd4b742e1bb8bbc33bc
Autor:
Rahul K. Suryawanshi, Chandrashekhar D. Patil, Alex Agelidis, Raghuram Koganti, Tejabhiram Yadavalli, Joshua M. Ames, Hemant Borase, Deepak Shukla
Publikováno v:
Science Advances. 9
Limited knowledge exists on exogenous DNA virus reinfections. Herpes simplex virus-1 (HSV-1), a prototype DNA virus, causes multiple human diseases including vision-threatening eye infections. While reinfection with an exogenous HSV-1 strain is consi
Autor:
Taha Y. Taha, Irene P. Chen, Jennifer M. Hayashi, Takako Tabata, Keith Walcott, Gabriella R. Kimmerly, Abdullah M. Syed, Alison Ciling, Rahul K. Suryawanshi, Hannah S. Martin, Bryan H. Bach, Chia-Lin Tsou, Mauricio Montano, Mir M. Khalid, Bharath K. Sreekumar, G. Renuka Kumar, Stacia Wyman, Jennifer A. Doudna, Melanie Ott
Publikováno v:
bioRxiv
Nature communications, vol 14, iss 1
Nature communications, vol 14, iss 1
Although the SARS-CoV-2 Omicron variant (BA.1) spread rapidly across the world and effectively evaded immune responses, its viral fitness in cell and animal models was reduced. The precise nature of this attenuation remains unknown as generating repl
Autor:
Taha Y. Taha, Rahul K. Suryawanshi, Irene P. Chen, Galen J. Correy, Patrick C. O’Leary, Manasi P. Jogalekar, Maria McCavitt-Malvido, Morgan E. Diolaiti, Gabriella R. Kimmerly, Chia-Lin Tsou, Luis Martinez-Sobrido, Nevan J. Krogan, Alan Ashworth, James S. Fraser, Melanie Ott
Publikováno v:
bioRxiv
Despite unprecedented efforts, our therapeutic arsenal against SARS-CoV-2 remains limited. The conserved macrodomain 1 (Mac1) in NSP3 is an enzyme exhibiting ADP-ribosylhydrolase activity and a possible drug target. To determine the therapeutic poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8197d088d3f7b4343977c88a4c32d846
https://europepmc.org/articles/PMC10153184/
https://europepmc.org/articles/PMC10153184/