Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Rahul K Lall"'
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119859 (2015)
Prostate cancer is a leading of cause of cancer related death in men. Despite intensive investment in improving early diagnosis, it often escapes timely detection. Mortality remains high in advanced stage prostate cancer where palliative care remains
Externí odkaz:
https://doaj.org/article/d9b8f82788d64896a6e8310e03b244b9
Autor:
Mario Sechi, Rahul K. Lall, Saheed O Afolabi, Anant Singh, Dinesh C. Joshi, Shing-Yan Chiu, Hasan Mukhtar, Deeba N. Syed
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract The anti-proliferative activity of dietary flavonoid fisetin has been validated in various cancer models. Establishing its precise mechanism of action has proved somewhat challenging given the multiplicity of its targets. We demonstrated tha
Externí odkaz:
https://doaj.org/article/5e2df20b2938453aa0b4f7b03494c319
Publikováno v:
Neuropsychiatric Disease and Treatment. 15:1343-1354
Alzheimer's disease (AD) is the most common neurodegenerative disease. Histological characterization of amyloid plaques and neurofibrillary tangles in the brains of AD patients, alongside genetic studies in individuals suffering the familial form of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a1c8f7aca63af5545c9276f0b06a3ed
https://doi.org/10.2147/ndt.s203103
https://doi.org/10.2147/ndt.s203103
Publikováno v:
Neural Development
Neural Development, Vol 15, Iss 1, Pp 1-9 (2020)
Neural Development, Vol 15, Iss 1, Pp 1-9 (2020)
As humans, we cannot regenerate axons within the central nervous system (CNS), therefore, making any damage to it permanent. This leads to the loss of sensory and motor function below the site of injury and can be crippling to a person’s health. Sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038f8d0041e881dcb8babded70bdea7b
Publikováno v:
Molecular Carcinogenesis. 57:653-663
Epithelial-to-mesenchymal transition (EMT) plays a crucial role in prostate cancer (PCa) metastasis. This has led to a surge in the efforts for identification of safer and more effective compounds which can modulate EMT and consequently inhibiting mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16924df77bd799bebf499cd91b639c6b
https://doi.org/10.1002/mc.22790
https://doi.org/10.1002/mc.22790
Autor:
Xu Shi, Robert E. Gerszten, Rahul K. Lall, Laurie A. Farrell, Marielle Scherrer-Crosbie, Igal A. Sebag, Aarti Asnani, Juan Carlos Plana
Publikováno v:
Journal of cardiovascular translational research. 13(3)
Anthracyclines and HER2-targeted antibodies are very effective for the treatment of breast cancer, but their use is limited by cardiotoxicity. In this nested case-control study, we assessed the role of intermediary metabolism in 38 women with breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfbf445b3eaec84cb591f6cef1feeade
https://pubmed.ncbi.nlm.nih.gov/31278494
https://pubmed.ncbi.nlm.nih.gov/31278494
Autor:
Wei Huang, Imtiaz A. Siddiqui, Hani Choudhry, Bushra Ateeq, Mario Sechi, Suvasmita Rath, James M. Ntambi, Hasan Mukhtar, Nishat Manzar, Vaqar M. Adhami, Rahul K. Lall, Thomas C. Havighurst, Mohammad Imran Khan, Abid Hamid, Ahmed Al Johani, Mazin A. Zamzami
Growth factor receptor-binding protein 10 (GRB10) is a well-known adaptor protein and a recently identified substrate of the mammalian target of rapamycin (mTOR). Depletion of GRB10 increases insulin sensitivity and overexpression suppresses PI3K/Akt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99602cee44ff75f4d841f2d15bac2b10
https://europepmc.org/articles/PMC6404554/
https://europepmc.org/articles/PMC6404554/
Autor:
Hasan Mukhtar, Rahul K. Lall, Dinesh C. Joshi, Anant Singh, Mario Sechi, Saheed O. Afolabi, Shing Yan Chiu, Deeba N. Syed
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports
Scientific Reports
The anti-proliferative activity of dietary flavonoid fisetin has been validated in various cancer models. Establishing its precise mechanism of action has proved somewhat challenging given the multiplicity of its targets. We demonstrated that YB-1 pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55f898402d5a858ad1a87af657ea5c0
https://doi.org/10.1038/s41598-018-33879-w
https://doi.org/10.1038/s41598-018-33879-w
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 2, Pp 3350-3376 (2015)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Prostate cancer is the most prevalent disease affecting males in many Western countries, with an estimated 29,480 deaths in 2014 in the US alone. Incidence rates for prostate cancer deaths have been decreasing since the early 1990s in men of all race
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b867eaab3574ed92e73c1214776b31e5
http://www.mdpi.com/1422-0067/16/2/3350
http://www.mdpi.com/1422-0067/16/2/3350
Autor:
Imtiaz A. Siddiqui, Deeba N. Syed, Dinesh C. Joshi, Rahul K. Lall, Mario Sechi, Vaqar M. Adhami, Omar Mohammad Haidar, Mohammad Imran Khan, Shing Yan Chiu, Hasan Mukhtar
Publikováno v:
Oncotarget
// Mohammad Imran Khan 1 , Vaqar Mustafa Adhami 1 , Rahul Kumar Lall 1 , Mario Sechi 3 , Dinesh C. Joshi 2 , Omar M. Haidar 1 , Deeba Nadeem Syed 1 , Imtiaz Ahmad Siddiqui 1 , Shing-Yan Chiu 2 , Hasan Mukhtar 1 1 Department of Dermatology, School of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::709c99025bbfc919c4d38863cc2bc2b4
http://europepmc.org/articles/PMC4058019
http://europepmc.org/articles/PMC4058019