Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Rahul Gokarn"'
Autor:
Samantha M. Solon-Biet, Sarah J. Mitchell, Sean C.P. Coogan, Victoria C. Cogger, Rahul Gokarn, Aisling C. McMahon, David Raubenheimer, Rafael de Cabo, Stephen J. Simpson, David G. Le Couteur
Publikováno v:
Cell Reports, Vol 11, Iss 10, Pp 1529-1534 (2015)
Both caloric restriction (CR) and low-protein, high-carbohydrate (LPHC) ad-libitum-fed diets increase lifespan and improve metabolic parameters such as insulin, glucose, and blood lipids. Severe CR, however, is unsustainable for most people; therefor
Externí odkaz:
https://doaj.org/article/5e413f3b03974ecc8c1d89c5aa4daf48
Autor:
Nicholas J. Hunt, Rahul Gokarn, Samantha M. Solon-Biet, David E. James, Alistair M. Senior, David G. Le Couteur, Gregory J. Cooney, Stephen J. Simpson, Amanda E. Brandon, Benjamin L. Parker, Tamara Pulpitel, David Raubenheimer, Jibran A Wali, Victoria C. Cogger
Publikováno v:
Cell metabolism. 33(12)
Nutrient sensing pathways influence metabolic health and aging, offering the possibility that diet might be used therapeutically, alone or with drugs targeting these pathways. We used the Geometric Framework for Nutrition to study interactive and com
Autor:
Michelle M. Adams, Cédric Albinet, Banu Alicioglu, Paolo Amami, Nathalie André, Narin Ilgim Ardic-Avci, Elizabeth Arslanoglou, Guilherme Giannini Artioli, Michel Audiffren, Hande Ozge Aydogan, Francisco Javier Belchí, Marvin H. Berman, Ondrej Bezdicek, Cynthia Bianco, Jasmina Boban, Carlos Roberto Bueno Júnior, Blake E. Butler, Daniele Cartelli, Augusto Pietro Casani, Dilan Celebi-Birand, Zikuan Chen, Zeyuan Chen, Bihong T. Chen, Katie E. Cherry, Christian Chicherio, Jeshya A. Chio, Pere Clavé, Victoria C. Cogger, Márcia Regina Cominetti, Ma Fe P. de Guzman, Maria Clarissa O. del Moral, Eimear Dolan, Jacqueline C. Dominguez, Premchand Dommaraju, Theresa Ebo, Melissa K. Edler, Begun Erbaba, Ghazaleh Eskandari-Sedighi, Delphine Fagot, Fereshteh Farajdokht, Isabel Fariñas, Laís Francielle Francisca Felício, Luiz Felipe da Silva Figueiredo, Karen L. Fortuna, Máximo Ibo Galindo, Ekavi N. Georgousopoulou, Rahul Gokarn, Gabriel Gold, Hayley Groetz, Bruno Gualano, G.M. Halliday, Erin E. Harrington, Claudia Heidenreich, Boris Henčić, Rafael Hernández, Björn Herrmann, Jasna Jančić, R.C. Jeżewski, Hulusi Kafaligonul, Hakki Muammer Karakas, Elif Tugce Karoglu-Eravsar, Dimitris Kiosses, Dusko Kozic, Enikö Kövari, Lewis H. Kuller, Thomas J. LaRocca, David G. Le Couteur, Gary Jek Chong Lee, Unax Lertxundi, Víctor López del Amo, Mariana Luciano de Almeida, Javad Mahmoudi, João O. Malva, Patricia Regina Manzine, Beatriz Martins, Douglas B. Matthews, Derval McCormack, Juan Medrano, Duane D. Mellor, Juan C. Meléndez, Jonas Mengel-From, Jelena Milić, Jody Monkovic, Renato Sobral Monteiro-Junior, Ricardo Moreira, Emily L. Munger, Elena Navari, M. Christopher Newland, João Novo, Reinaldo B. Oriá, Fiadhnait O’Keeffe, Demosthenes B. Panagiotakos, Frederico C. Pereira, Ana Perez-Villalba, Rafaela Peron, Victor R. Preedy, Mary Ann Raghanti, Simona Raimo, Rajkumar Rajendram, Ana López Ramírez, Ramon Raposo, David Raubenheimer, Punam Rawal, Celinda Reese-Melancon, Hannah Reich, Carmen Requena, Carlos Fontes Ribeiro, Ana Carolina de Mello Alves Rodrigues, Luis Miguel Rondón García, Rosa Raquel Ruiz Trascastro, Saeed Sadigh-Eteghad, Farzad Salehpour, Janko Samardžić, Gabriella Santangelo, Encarnación Satorres, Andrew N. Shen, C.E. Shepherd, Stephen J. Simpson, Marina Yazigi Solis, Samantha M. Solon-Biet, Dunja Stankić, Timo E. Strandberg, Astrid M. Suchy-Dicey, Andrea Tapia, Majda M. Thurnher, Paula Álvarez-Merino, Noemí Tomsen, Luigi Trojano, Melek Umay Tuz-Sasik, Henryk F. Urbanski, Rodrigo Portes Ureshino, Ed van Beeck, Candice E. Van Skike, Izabela Pereira Vatanabe, Devin Wahl, David Westaway, Shawn Wong, Long Wu, Túlio Brandão Xavier-Rocha, Janko Zeković, Xin Zhang, Liqin Zhao
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29030ec9d0d9b573eaa7429179db2306
https://doi.org/10.1016/b978-0-12-818000-6.01002-7
https://doi.org/10.1016/b978-0-12-818000-6.01002-7
Autor:
Victoria C. Cogger, Stephen J. Simpson, Samantha M. Solon-Biet, Thomas J. LaRocca, Devin Wahl, David G. Le Couteur, David Raubenheimer, Rahul Gokarn
Publikováno v:
Assessments, Treatments and Modeling in Aging and Neurological Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17e8725722faea8a159199ad5aa6be04
https://doi.org/10.1016/b978-0-12-818000-6.00046-9
https://doi.org/10.1016/b978-0-12-818000-6.00046-9
Autor:
Samantha M. Solon-Biet, J. William O. Ballard, Gregory J. Cooney, Devin Wahl, Victoria C. Cogger, Rahul Gokarn, David Raubenheimer, Margaret J. Morris, Neil A. Youngson, David G. Le Couteur, Aisling C. McMahon, Stephen J. Simpson
Publikováno v:
The Journals of Gerontology: Series A. 73:446-449
Macronutrients and dietary energy influence aging, age-related health, and life span. Reduction in telomere length has been proposed as one mechanism for aging. Therefore, this study investigated the effects of varying ratios of dietary macronutrient
Autor:
Stephen J. Simpson, Victoria C. Cogger, David G. Le Couteur, Rafael de Cabo, Samantha M. Solon-Biet, Devin Wahl, Sarah J. Mitchell, Rahul Gokarn
Publikováno v:
Nutrition and Healthy Aging
Background Sirtuin 1 (SIRT1) is a NAD+-dependent enzyme that has important roles in many biological processes involved in aging, including cell growth and repair, inflammation, and energy regulation. SIRT1 activity is modulated in response to certain
Autor:
Mark P. Mattson, Rahul Gokarn, Rafael de Cabo, David G. Le Couteur, Samantha M. Solon-Biet, Stephen J. Simpson, Tamara Pulpitel, Victoria C. Cogger, David Raubenheimer, Rosilene V. R. Waern, Devin Wahl
Publikováno v:
Ageing Research Reviews. 31:80-92
Old age is the greatest risk factor for most neurodegenerative diseases. During recent decades there have been major advances in understanding the biology of aging, and the development of nutritional interventions that delay aging including calorie r
Autor:
Jibran A Wali, Samantha M. Solon-Biet, Rahul Gokarn, David E. James, David G. Le Couteur, Stephen J. Simpson, Fleur Ponton, Tamara Pulpitel, Christopher D. Morrison, Kirsty A Walters, Victoria C. Cogger, Marika Heblinski, Arthur D. Conigrave, Kari Ruohonen, David Raubenheimer, James R. Krycer, Aisling C. McMahon, Jessica Durrant-Whyte, Devin Wahl, Alessandra Warren
Publikováno v:
Cell Metabolism. 24:555-565
Fibroblast growth factor 21 (FGF21) is the first known endocrine signal activated by protein restriction. Although FGF21 is robustly elevated in low-protein environments, increased FGF21 is also seen in various other contexts such as fasting, overfee
Autor:
James R. Mitchell, Sarah J. Mitchell, Christopher Hine, Aisling C. McMahon, Victoria C. Cogger, Rafael de Cabo, Devin Wahl, David G. Le Couteur, Rahul Gokarn, David Raubenheimer, Gregory J. Cooney, Samantha M. Solon-Biet, Stephen J. Simpson
Nutrition influences both hepatic function and aging, but mechanisms are poorly understood. Here, the effects of lifelong, ad libitum-fed diets varying in macronutrients and energy on hepatic gene expression were studied. Gene expression was measured
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763f7f5f3ceda39944ed7d6cb646da93
https://europepmc.org/articles/PMC6454416/
https://europepmc.org/articles/PMC6454416/
Autor:
Sarah J. Mitchell, Rafael de Cabo, Rahul Gokarn, Sean C. P. Coogan, Samantha M. Solon-Biet, David Raubenheimer, Aisling C. McMahon, David G. Le Couteur, Stephen J. Simpson, Victoria C. Cogger
Publikováno v:
Cell Reports, Vol 11, Iss 10, Pp 1529-1534 (2015)
SummaryBoth caloric restriction (CR) and low-protein, high-carbohydrate (LPHC) ad-libitum-fed diets increase lifespan and improve metabolic parameters such as insulin, glucose, and blood lipids. Severe CR, however, is unsustainable for most people; t