A triazine-based BODIPY trimer as a molecular viscometer

Autor: Sergei V. Dzyuba, Joseph Kimball, Ignacy Gryczynski, Zygmunt Gryczynski, Ilkay Bora, Hana Jaafari, Rahul Chib, Nicholas W. Smith, Marlius Castillo, Rafal Fudala, Sangram Raut

Publikováno v: Raut, S L, Kimball, J D, Fudala, R, Bora, I, Chib, R, Jaafari, H, Castillo, M K, Smith, N W, Gryczynski, I, Dzyuba, S V & Gryczynski, Z 2016, ' A triazine-based BODIPY trimer as a molecular viscometer ', Physical Chemistry Chemical Physics, vol. 18, no. 6, pp. 4535-4540 . https://doi.org/10.1039/c5cp07214j

Photophysical behaviour of a novel trimeric BODIPY rotor with a high extinction coefficient is reported. Steady state and time resolved fluorescence measurements established that the trimer could be used as a viscometer for molecular solvents, membra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070a3b67be5dc74493d42cdc1a5aca0b
https://doi.org/10.1039/c5cp07214j

Evidence of energy transfer from tryptophan to BSA/HSA protected gold nanoclusters

Autor: Sangram Raut, Susan Butler, Julian Borejdo, Zygmunt Gryczynski, Rahul Chib, Ignacy Gryczynski

Publikováno v: Methods and applications in fluorescence. 2(3)

This work reports on the chromophores interactions within protein-protected gold nanoclusters. We conducted spectroscopic studies of fluorescence emissions originated from gold nanoclusters and intrinsic tryptophan (Trp) in BSA or HSA proteins. Both

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035b458476dfbc56193d85e86e1d4220
https://pubmed.ncbi.nlm.nih.gov/29148473

FRET Based Ratio-Metric Sensing of Hyaluronidase in Synthetic Urine as a Biomarker for Bladder and Prostate Cancer

Autor: Aaron Chang, Mark E. Mummert, Ignacy Gryczynski, Rahul Chib, Sangram Raut, Ryan Rich, Zygmunt Gryczynski, Rafal Fudala

Publikováno v: Current Pharmaceutical Biotechnology. 14:470-474

Elevated hyaluronidase levels are found in the urine of bladder and prostate cancer patients. Therefore, HA-ase is regarded as an important biomarker for the detection of these cancers. In this report, we use a FRET based ratiometric sensing approach

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b88d5c58a0f8d0ec61d9c716e3533b
https://doi.org/10.2174/13892010113149990222

Fluorescent biosensor for the detection of hyaluronidase: intensity-based ratiometric sensing and fluorescence lifetime-based sensing using a long lifetime azadioxatriangulenium (ADOTA) fluorophore

Autor: Rahul Chib, Ignacy Gryczynski, Zygmunt Gryczynski, Ilkay Bora, Rafal Fudala, Robert Pendry, Mark E. Mummert, Sunil Shah, Julian Borejdo, Bo W. Laursen

Publikováno v: Analytical and bioanalytical chemistry. 408(14)

In this report, we have designed a rapid and sensitive, intensity-based ratiometric sensing as well as lifetime-based sensing probe for the detection of hyaluronidase activity. Hyaluronidase expression is known to be upregulated in various pathologic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf63ffcc5a2da5cc5416d2aa40e53f78
https://pubmed.ncbi.nlm.nih.gov/26993308

Associated Anisotropy Decays of Ethidium Bromide Interacting with DNA

Autor: Rahul Chib, Preeti Singhal, Zygmunt Gryczynski, Sangram Raut, Ignacy Gryczynski, Sarika Sabnis

Publikováno v: Methods and applications in fluorescence. 2(1)

Ethidium Bromide (EB) is a commonly used dye in a deoxyribonucleic acid (DNA) study. Upon an intercalation, this dye significantly increases its brightness and fluorescence lifetime. In this report we have studied the time resolved fluorescence prope

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc16657634e9b7c4baad213e6fdcf9f
https://pubmed.ncbi.nlm.nih.gov/26640693