Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Rahul, Mannan"'
Autor:
Anbarasu Kumaraswamy, Zhi Duan, Diana Flores, Chao Zhang, Archana Sehrawat, Ya-Mei Hu, Olivia A. Swaim, Eva Rodansky, William K. Storck, Joshua A. Kuleape, Karan Bedi, Rahul Mannan, Xiao-Ming Wang, Aaron Udager, Visweswaran Ravikumar, Armand Bankhead III, Ilsa Coleman, John K. Lee, Colm Morrissey, Peter S. Nelson, Arul M. Chinnaiyan, Arvind Rao, Zheng Xia, Joel A. Yates, Joshi J. Alumkal
Publikováno v:
JCI Insight, Vol 8, Iss 15 (2023)
Lysine-specific demethylase 1 (LSD1) is a histone demethylase that promotes stemness and cell survival in cancers such as prostate cancer. Most prostate malignancies are adenocarcinomas with luminal differentiation. However, some tumors undergo cellu
Externí odkaz:
https://doaj.org/article/e4a07a2910524a9eab732b3ab8ace38b
Autor:
Chandan Kumar-Sinha, Pankaj Vats, Nguyen Tran, Dan R. Robinson, Valerie Gunchick, Yi-Mi Wu, Xuhong Cao, Yu Ning, Rui Wang, Erica Rabban, Janice Bell, Sunita Shankar, Rahul Mannan, Yuping Zhang, Mark M. Zalupski, Arul M. Chinnaiyan, Vaibhav Sahai
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 42, Iss , Pp 100910- (2023)
Background: Biliary tract cancers (BTCs) including intrahepatic, perihilar, and distal cholangiocarcinoma as well as gallbladder cancer, are rare but aggressive malignancies with few effective standard of care therapies. Methods: We implemented integ
Externí odkaz:
https://doaj.org/article/267f07005d4148529c8e940f763e1135
Autor:
Josh N. Vo, Yi-Mi Wu, Jeanmarie Mishler, Sarah Hall, Rahul Mannan, Lisha Wang, Yu Ning, Jin Zhou, Alexander C. Hopkins, James C. Estill, Wallace K. B. Chan, Jennifer Yesil, Xuhong Cao, Arvind Rao, Alexander Tsodikov, Moshe Talpaz, Craig E. Cole, Jing C. Ye, Multiple Myeloma Research Consortium, P. Leif Bergsagel, Daniel Auclair, Hearn Jay Cho, Dan R. Robinson, Arul M. Chinnaiyan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The genetic factors involved in disease progression and drug resistance in multiple myeloma (MM) are varied and complex. Here, genomic and transcriptomic profiling of 511 relapsed and refractory MM patients reveals genetic alterations in several onco
Externí odkaz:
https://doaj.org/article/f655f451b78e4e7097fa8cd313e2e43d
Autor:
Vipulkumar Dadhania, Daniel Gonzalez, Mustafa Yousif, Jerome Cheng, Todd M. Morgan, Daniel E. Spratt, Zachery R. Reichert, Rahul Mannan, Xiaoming Wang, Anya Chinnaiyan, Xuhong Cao, Saravana M. Dhanasekaran, Arul M. Chinnaiyan, Liron Pantanowitz, Rohit Mehra
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background TMPRSS2-ERG gene rearrangement, the most common E26 transformation specific (ETS) gene fusion within prostate cancer, is known to contribute to the pathogenesis of this disease and carries diagnostic annotations for prostate cance
Externí odkaz:
https://doaj.org/article/6aa8b0e8ad3d49c0bb4daed53a3894ce
Autor:
Hasandeep Singh, Ripdaman Singh, Sarabjit kaur, Rohit Arora, Rahul Mannan, Harpal Singh Buttar, Saroj Arora, Balbir Singh
Publikováno v:
Journal of Ayurveda and Integrative Medicine, Vol 11, Iss 4, Pp 391-398 (2020)
Background: Phyllanthus fraternus is a pantropical weed of family phyllanthaceae, mainly found in northeast India. It has been used in the folklore medicine of Manipur tribe for treating type 2 diabetes. Objective: The present study was commenced to
Externí odkaz:
https://doaj.org/article/6ef46ffa069d48019f8d4367e2995bb7
Autor:
Sunita Shankar, Jean Ching-Yi Tien, Ronald F. Siebenaler, Seema Chugh, Vijaya L. Dommeti, Sylvia Zelenka-Wang, Xiao-Ming Wang, Ingrid J. Apel, Jessica Waninger, Sanjana Eyunni, Alice Xu, Malay Mody, Andrew Goodrum, Yuping Zhang, John J. Tesmer, Rahul Mannan, Xuhong Cao, Pankaj Vats, Sethuramasundaram Pitchiaya, Stephanie J. Ellison, Jiaqi Shi, Chandan Kumar-Sinha, Howard C. Crawford, Arul M. Chinnaiyan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Argonaute 2 (AGO2) binds RAS and is required for cellular transformation. Here, the authors establish a KRAS-driven mouse model of pancreatic cancer with conditional loss of AGO2 and show that the early phase of neoplastic lesion initiation is depend
Externí odkaz:
https://doaj.org/article/4879439f815846169a9d5e62cae6d7c2
Autor:
Manpreet Kaur, Tejinder Singh Bhasin, Mridu Manjari, Rahul Mannan, Sonam Sharma, Gurupriya Anand
Publikováno v:
Journal of Pathology of Nepal, Vol 8, Iss 1, Pp 1289-1296 (2018)
Background: Gastrointestinal tract endoscopy along with biopsy is an established procedure for investigating a wide range of gastrointestinal conditions especially inflammatory and malignant diseases. The aim was to study and categorizing the morphol
Externí odkaz:
https://doaj.org/article/7af82fe60baf4ba4875ff51619abeb6a
Publikováno v:
Cell & Bioscience, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Cancer, the main cause of human deaths in the modern world is a group of diseases. Anticancer drug discovery is a challenge for scientists because of involvement of multiple survival pathways of cancer cells. An extensive study on the regula
Externí odkaz:
https://doaj.org/article/aaeab174b5fd48bf9aaeef7e08be1c54
Autor:
Richard L. Cantley, Xiaoming Wang, Zachery R. Reichert, Arul M. Chinnaiyan, Rahul Mannan, Xuhong Cao, Daniel E. Spratt, Ulka N. Vaishampayan, Joshi J. Alumkal, Todd M. Morgan, Ganesh Palapattu, Matthew S. Davenport, Liron Pantanowitz, Rohit Mehra
Publikováno v:
Cancer Cytopathology. 131:117-135
The diagnosis of metastatic prostatic cancer (MPC) by fine needle aspiration (FNA) can usually be rendered by typical cytomorphologic and immunohistochemical (IHC) features. However, MPC diagnosis may be complicated by transformation to atypical phen
Autor:
Jasmeet Kaur, Rahul Mannan, Mridu Manjari, Sonam Sharma, Jasmine Kaur, Tejinder Singh Bhasin, Amritpal Kaur
Publikováno v:
Journal of Pathology of Nepal, Vol 7, Iss 2, Pp 1141-1148 (2017)
Background: In recent years, p53 has emerged as an important tool for not only diagnosis and predicting prognosis in head and neck squamous cell carcinoma. The aim of this study was to find the role of p53 staining intensity in determining prognosis.
Externí odkaz:
https://doaj.org/article/7c2a49be9c854010837f2e1c3bc4dc9e