Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Rahul, Kalla"'
Autor:
Jie Chen, Han Zhang, Tian Fu, Jianhui Zhao, Jan Krzysztof Nowak, Rahul Kalla, Judith Wellens, Shuai Yuan, Alexandra Noble, Nicholas T. Ventham, Malcolm G. Dunlop, Jonas Halfvarson, Ren Mao, Evropi Theodoratou, Jack Satsangi, Xue Li
Publikováno v:
EBioMedicine, Vol 110, Iss , Pp 105443- (2024)
Summary: Background: This study aims to confirm the associations of air pollution with ulcerative colitis (UC) and Crohn's disease (CD); to explore interactions with genetics and lifestyle; and to characterize potential epigenetic mechanisms. Methods
Externí odkaz:
https://doaj.org/article/2f7b2d8722784ab88ccf8c0ceb2b28a7
Autor:
Han Zhang, Rahul Kalla, Jie Chen, Jianhui Zhao, Xuan Zhou, Alex Adams, Alexandra Noble, Nicholas T. Ventham, Judith Wellens, Gwo-Tzer Ho, Malcolm G. Dunlop, Jan Krzysztof Nowak, Yuan Ding, Zhanju Liu, Jack Satsangi, Evropi Theodoratou, Xue Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract This work aims to investigate how smoking exerts effect on the development of inflammatory bowel disease (IBD). A prospective cohort study and a Mendelian randomization study are first conducted to evaluate the association between smoking be
Externí odkaz:
https://doaj.org/article/04a74e10927f428d84730e560996c873
Autor:
Nicholas T. Ventham, Nicholas A. Kennedy, Rahul Kalla, Alex T. Adams, Alexandra Noble, Holly Ennis, Craig Mowat, Malcolm G. Dunlop, Jack Satsangi, Ian Arnott, Aiden Cahill, Malcolm Smith, Tariq Ahmad, Sreedhar Subramanian, Simon Travis, John Morris, John Hamlin, Anjan Dhar, Chuka Nwokolo, Cathryn Edwards, Tom Creed, Stuart Bloom, Mohamed Yousif, Linzi Thomas, Simon Campbell, Stephen J. Lewis, Shaji Sebastian, Sandip Sen, Simon Lal, Chris Hawkey, Charles Murray, Fraser Cummings, Jason Goh, James O. Lindsay, Naila Arebi, Lindsay Potts, Aileen J. McKinley, John M. Thomson, John A. Todd, Mhairi Collie, Ashley Mowat, Daniel R. Gaya, Jack Winter, Graham D. Naismith, Catriona Keerie, Steff Lewis, Robin J. Prescott, Gordan Lauc, Harry Campbell, Dermot P.B. McGovern, Vito Annese, Vlatka Zoldoš, Iain K. Permberton, Manfred Wuhrer, Daniel Kolarich, Daryl L. Fernandes, Evropi Theorodorou, Victoria Merrick Daniel I. Spencer, Richard A. Gardner, Ray Doran, Archana Shubhakar, Ray Boyapati, Igor Rudan, Paolo Lionetti, Irena Trbojević Akmačić, Jasminka Krištić, Frano Vuč ković, Jerko Štambuk, Mislav Novokmet, Maja Pučić-Baković, Olga Gornik, Angelo Andriulli, Laura Cantoro, Giancarlo Sturniolo, Gionata Fiorino, Natalia Manetti, Anna Latiano, Anna Kohn, Renata D’Inca`, Silvio Danese, Ian D. Arnott, Colin L. Noble, Charlie W. Lees, Alan G. Shand, Gwo-Tzer Ho, Lee Murphy, Jude Gibson, Louise Evenden, Nicola Wrobel, Tamara Gilchrist, Angie Fawkes, Guinevere S.M. Kammeijer, Florent Clerc, Noortje de Haan, Aleksandar Vojta, Ivana Samaržija, Dora Markulin, Marija Klasić, Paula Dobrinić, Yurii Aulchenko, Tim van den Heuve, Daisy Jonkers, Marieke Pierik
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 3, Pp 431-450 (2023)
Background & Aims: DNA methylation alterations may provide important insights into gene-environment interaction in cancer, aging, and complex diseases, such as inflammatory bowel disease (IBD). We aim first to determine whether the circulating DNA me
Externí odkaz:
https://doaj.org/article/f32b67ecfa854c6487a3c5196a5070e3
Autor:
Jie Chen, Judith Wellens, Rahul Kalla, Tian Fu, Minzi Deng, Han Zhang, Shuai Yuan, Xiaoyan Wang, Evropi Theodoratou, Xue Li, Jack Satsangi
Publikováno v:
Chen, J, Wellens, J, Kalla, R, Fu, T, Deng, M, Zhang, H, Yuan, S, Wang, X, Theodoratou, E, Li, X & Satsangi, J 2022, ' Intake of ultra-processed foods is associated with an increased risk of Crohn's disease : a cross-sectional and prospective analysis of 187,154 participants in the UK Biobank ', Journal of Crohn's and Colitis . https://doi.org/10.1093/ecco-jcc/jjac167
Background and Aims Ultra-processed food [UPF] consumption has been linked to globally increasing incidence and prevalence of chronic diseases, including inflammatory bowel diseases [IBD]. We aimed to investigate the association between UPF consumpti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b53cf60e9209c73c9f3a3e94f0c6e99e
https://doi.org/10.1093/ecco-jcc/jjac167
https://doi.org/10.1093/ecco-jcc/jjac167
Publikováno v:
F1000Research, Vol 9 (2020)
Crohn’s disease and ulcerative colitis are increasingly prevalent, relapsing and remitting inflammatory bowel diseases (IBDs) with variable disease courses and complications. Their aetiology remains unclear but current evidence shows an increasingl
Externí odkaz:
https://doaj.org/article/ac0a57b517704aaca8e7f43e0238dac5
Autor:
Jianhui Zhao, Jie Chen, Yuhao Sun, Shuai Yuan, Judith Wellens, Rahul Kalla, Evropi Theodoratou, Xue Li, Jack Satsangi
Publikováno v:
Zhao, J, Chen, J, Sun, Y, Yuan, S, Wellens, J, Kalla, R, Theodoratou, E, Li, X & Satsangi, J 2023, ' Defining gene–lifestyle interactions in inflammatory bowel disease : progress towards understanding disease pathogenesis ', Gut . https://doi.org/10.1136/gutjnl-2023-329875
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc1a4bfd5c43d961259a23346577b50
https://www.pure.ed.ac.uk/ws/files/339515149/Modifiable_lifestyle_factors_for_the_prevention_of_inflammatory_bowel_disease.pdf
https://www.pure.ed.ac.uk/ws/files/339515149/Modifiable_lifestyle_factors_for_the_prevention_of_inflammatory_bowel_disease.pdf
Publikováno v:
Journal of Crohn's and Colitis.
Biomarkers to guide clinical decision making at diagnosis of inflammatory bowel disease [IBD] are urgently needed. We investigated a composite serum N-glycomic biomarker to predict future disease course in a discovery cohort of 244 newly diagnosed IB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95fa27331ca69306a46c1689fd35f7df
https://doi.org/10.1093/ecco-jcc/jjad012
https://doi.org/10.1093/ecco-jcc/jjad012
Autor:
Yuhao Sun, Shuai Yuan, Xuejie Chen, Jing Sun, Rahul Kalla, Lili Yu, Lijuan Wang, Xuan Zhou, Xiangxing Kong, Therese Hesketh, Gwo-tzer Ho, Kefeng Ding, Malcolm Dunlop, Susanna C. Larsson, Jack Satsangi, Jie Chen, Xiaoyan Wang, Xue Li, Evropi Theodoratou, Edward L Giovannucci
Publikováno v:
Sun, Y, Yuan, S, Chen, X, Sun, J, Kalla, R, Yu, L, Wang, L, Zhou, X, Kong, X, Hesketh, T, Ho, G-T, Ding, K, Dunlop, M G, Larsson, S C, Satsangi, J, Chen, J, Wang, X, Li, X, Theodoratou, E & Giovannucci, E L 2023, ' The contribution of genetic risk and lifestyle factors in the development of adult-onset inflammatory bowel disease : a prospective cohort study ', The American Journal of Gastroenterology, vol. 118, no. 3, pp. 511-522 . https://doi.org/10.14309/ajg.0000000000002180
SummaryObjectiveThere are few prospective data exploring the combined effect of genetic and lifestyle factors on the incidence of inflammatory bowel disease (IBD), and whether genetic risk of IBD may be mitigated by lifestyle remains unclear.DesignWe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89327c84039adfbb5e0337640fccd465
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-507039
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-507039
Autor:
Mauro D'Amato, Petr Ricanek, Alex Adams, Jonas Christoffer Lindstrøm, Nicholas A. Kennedy, Morten H. Vatn, Fernando Gomollón, Nicholas T. Ventham, Jonas Halfvarson, Christine Olbjørn, Rahul Kalla, Johan D. Söderholm, Daniel Bergemalm, Simen Vatn, Rebecca C Richmond, Jan Krzysztof Nowak, Caroline L Relton, Jørgen Jahnsen, Jack Satsangi, Marieke Pierik
Publikováno v:
Journal of Crohn's & Colitis, 17(2), 170-184. Oxford University Press
Background Epigenetic alterations may provide valuable insights into gene–environment interactions in the pathogenesis of inflammatory bowel disease [IBD]. Methods Genome-wide methylation was measured from peripheral blood using the Illumina 450k p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079c3041e49e3aea6df6864b62c84c43
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-190960
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-190960
Autor:
Rahul Kalla, Marianne Smith, Sarah-Louise Gillespie, Gail S M Masterton, William M Brindle, Eleanor F Watson, Nicholas I Church, Alexander R Robertson, Ian D. Penman, Angus Wallace, Rebecca K Grant, Colin L. Noble, John N. Plevris, Meghan Suddaby, Christian P. Selinger
Publikováno v:
Brindle, W M, Grant, R K, Smith, M, Suddaby, M, Wallace, W A, Gillespie, S-L, Church, N I, Noble, C L, Penman, I, Plevris, J, Robertson, A, Watson, E, P. Selinger, C & Kalla, R & Masterton, G S 2021, ' Risk stratifying gastric ulcers : Development and validation of a scoring system ', Frontline Gastroenterology, vol. 13, no. 2, pp. 111-118 . https://doi.org/10.1136/flgastro-2020-101759
Frontline Gastroenterol
Frontline Gastroenterol
ObjectiveDebate is ongoing regarding the need for universal endoscopic follow-up to ensure gastric ulcer healing. We aimed to assess the value of follow-up oesophago-gastro-duodenoscopies (OGDs) for gastric ulcer healing and stratify patients accordi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::966821b590f5eee02bc7c43a0c7141a2
https://doi.org/10.1136/flgastro-2020-101759
https://doi.org/10.1136/flgastro-2020-101759