Výsledky vyhledávání - "Rahmel, Tim (Dr. med.)"

The \(\it NF{\kappa}B1\) promoter polymorphism (-94ins/delATTG) is associated with susceptibility to cytomegalovirus infection after kidney transplantation and should have implications on CMV prophylaxis regimens

Autor: Nowak, Hartmuth Sebastian Burkhard (Dr. med.), Vornweg, Svenja (Dr. med.), Rump, Katharina (Dr. rer. nat.), Rahmel, Tim (Dr. med.), Unterberg, Matthias, Koos, Björn, Schenker, Peter (Prof. Dr. med.), Viebahn, Richard (Prof. Dr. med.), Adamzik, Michael (Prof. Dr. med.), Bergmann, Lars (Dr. med.)

Infections with cytomegalovirus (CMV) are one of the most frequent opportunistic infections in kidney transplant recipients. Current risk-adapted CMV chemoprophylaxis regimens are based almost solely on the donor and recipient CMV serostatus. Of note

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3579::9e63bcd71a070711da31d2af8b62a143
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/frontdoor/index/index/docId/8233

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Impact of carbohydrate-reduced nutrition in septic patients on ICU

Autor: Rahmel, Tim (Dr. med.), Hübner, Max, Koos, Björn, Wolf, Alexander (Dr. med.), Willemsen, Katrin, Strauß, Gabriele (Dr. med.), Effinger, David, Adamzik, Michael (Prof. Dr. med.), Kreth, Simone (PD Dr. med.)

\(\bf Introduction\) Sepsis is defined as detrimental immune response to an infection. This overwhelming reaction often abolishes a normal reconstitution of the immune cell homeostasis that in turn increases the risk for further complications. Recent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3579::4725fa2ed23c488e0d91a35d81670ac7
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/frontdoor/index/index/docId/7814

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The aquaporin 3 promoter polymorphism − 1431 A/G is associated with acute graft rejection and cytomegalovirus infection in kidney recipients due to altered immune cell migration

Autor: Rump, Katharina (Dr. rer. nat.), Rahmel, Tim (Dr. med.), Rustige, Anna-Maria (Dr. med.), Unterberg, Matthias, Nowak, Hartmuth Sebastian Burkhard (Dr. med.), Koos, Björn, Schenker, Peter (Prof. Dr. med.), Viebahn, Richard (Prof. Dr. med.), Adamzik, Michael (Prof. Dr. med.), Bergmann, Lars (Dr. med.)

Major complications after kidney transplantation are graft rejection and cytomegalovirus (CMV) infection, which are related to T-cell function, which depends on aquaporin 3 (AQP3) expression. The impact of the AQP3 A(−1431)G promoter polymorphism i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3579::c2d80a0b05e0301ce572c574d5fe5a5a
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/files/7587/RumpKatharina.pdf

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Major adverse kidney events are associated with the aquaporin 5-1364A/C promoter polymorphism in sepsis

Autor: Bergmann, Lars (Dr. med.), Nowak, Hartmuth Sebastian Burkhard (Dr. med.), Siffert, Winfried (Prof. Dr. med.), Peters, Jürgen, Adamzik, Michael (Prof. Dr. med.), Koos, Björn, Rahmel, Tim (Dr. med.)

Since the functionally important \(\it AQP5\) -1364A/C single nucleotide promoter polymorphism alters key mechanisms of inflammation and survival in sepsis, it may affect the risk of an acute kidney injury. Accordingly, we tested the hypothesis in se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3579::7e730a9f779af07195f666d89b17c14d
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/files/7434/Supplement1.pdf

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Long-term mortality and outcome in hospital survivors of septic shock, sepsis, and severe infections

Autor: Rahmel, Tim (Dr. med.), Schmitz, Stefanie, Nowak, Hartmuth Sebastian Burkhard (Dr. med.), Schepanek, Kaspar, Bergmann, Lars (Dr. med.), Halberstadt, Peter, Hörter, Stefan (Dipl.), Peters, Jürgen, Adamzik, Michael (Prof. Dr. med.)

Patients with severe infections and especially sepsis have a high in-hospital mortality, but even hospital survivors face long-term sequelae, decreased health-related quality of life, and high risk of death, suggesting a great need for specialized af

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3579::86bce02231a12acaf6013439e93b1a29
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/files/7678/RahmelTim3.pdf

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DNA methylation of a NF-\(\kappa\)B binding site in the aquaporin 5 promoter impacts on mortality in sepsis

Autor: Rump, Katharina (Dr. rer. nat.), Unterberg, Matthias, Dahlke, Agnes Maria, Nowak, Hartmuth Sebastian Burkhard (Dr. med.), Koos, Björn, Bergmann, Lars (Dr. med.), Siffert, Winfried (Prof. Dr. med.), Schäfer, Simon Thomas (Dr. med.), Peters, Jürgen, Adamzik, Michael (Prof. Dr. med.), Rahmel, Tim (Dr. med.)

Altered aquaporin 5 (\(\it AQP5\)) expression in immune cells impacts on key mechanisms of inflammation and is associated with sepsis survival. Since epigenetic regulation via DNA methylation might contribute to a differential \(\it AQP5\) expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3579::07d25d2ef008c1e58f5001bfca6f728f
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/files/7747/RahmelTim7.pdf

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The aquaporin 5 −1364A/C promoter polymorphism is associated with cytomegalovirus infection risk in kidney transplant recipients

Autor: Rahmel, Tim (Dr. med.), Nowak, Hartmuth Sebastian Burkhard (Dr. med.), Frisenda, Sandra (Dr. med.), Rump, Katharina (Dr. rer. nat.), Koos, Björn, Schenker, Peter (Prof. Dr. med.), Viebahn, Richard (Prof. Dr. med.), Adamzik, Michael (Prof. Dr. med.), Bergmann, Lars (Dr. med.)

\(\bf Background:\) The aquaporin 5 (AQP5) −1364A/C promoter single nucleotide polymorphism affects key mechanisms of inflammation and immune cell migration. Thus, it could be involved in the pathogenesis of cytomegalovirus infection. Accordingly,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3579::1830a24cd0e140484b2dc3e309b418c6
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/frontdoor/index/index/docId/7262

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A novel understanding of postoperative complications

Autor: Holtkamp, Caroline, Koos, Björn, Unterberg, Matthias, Rahmel, Tim (Dr. med.), Bergmann, Lars (Dr. med.), Bazzi, Zainab, Bazzi, Maha, Bukhari, Hassan, Adamzik, Michael (Prof. Dr. med.), Rump, Katharina (Dr. rer. nat.)

\(\bf Background\) Propofol is a widely used anaesthetic drug with advantageous operating conditions and recovery profile. However, propofol could have long term effects on neuronal cells and is associated with post-operative delirium (POD). In this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3579::0beaf81b5f29a806b70ecd060b4d3850
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/frontdoor/index/index/docId/7187

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Evaluation of inhaled salbutamol effectiveness under supportive use of electrical impedance tomography in ventilated ICU patients

Autor: Rahmel, Tim (Dr. med.), Koniusch, Alexandra, Schwertner, Martin, Oprea, Günther, Adamzik, Michael (Prof. Dr. med.), Nowak, Hartmuth Sebastian Burkhard (Dr. med.)

\(\bf Introduction\) The inhalative administration of drugs is a non-invasive application form that is regularly used in the treatment of ventilated patients in critical care setting. However, assessment of effectiveness or distribution of nebulised

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3579::2cef0faccf234be88000cda855829142
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/files/7129/RahmelTim5.pdf

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