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pro vyhledávání: '"Rahma M. Elbagoury"'
Autor:
Rahma M. Elbagoury, Miriam A. Shenouda, Heba E. Elnakib, Jannette Wober, Ashraf H. Abadi, Nermin S. Ahmed
Publikováno v:
Bioorganic chemistry. 131
Tamoxifen (TAM) is used in treatment of hormonal dependent breast cancer, both in premenopausal and postmenopausal women. TAM is intrinsically metabolized by CYP450 enzymes to more active metabolites. Recent reports identified CYP2D6, an enzyme invol