Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Rahel Kasonta"'
Autor:
Anne Rechtien, Laura Richert, Hadrien Lorenzo, Gloria Martrus, Boris Hejblum, Christine Dahlke, Rahel Kasonta, Madeleine Zinser, Hans Stubbe, Urte Matschl, Ansgar Lohse, Verena Krähling, Markus Eickmann, Stephan Becker, Selidji Todagbe Agnandji, Sanjeev Krishna, Peter G. Kremsner, Jessica S. Brosnahan, Philip Bejon, Patricia Njuguna, Marylyn M. Addo, Claire-Anne Siegrist, Angela Huttner, Marie-Paule Kieny, Vasee Moorthy, Patricia Fast, Barbara Savarese, Olivier Lapujade
Publikováno v:
Cell Reports, Vol 20, Iss 9, Pp 2251-2261 (2017)
Predicting vaccine efficacy remains a challenge. We used a systems vaccinology approach to identify early innate immune correlates of antibody induction in humans receiving the Ebola vaccine rVSV-ZEBOV. Blood samples from days 0, 1, 3, 7, and 14 were
Externí odkaz:
https://doaj.org/article/b6715c79bca245bab050971e0d2eb903
Autor:
Christine Dahlke, Rahel Kasonta, Sebastian Lunemann, Verena Krähling, Madeleine E. Zinser, Nadine Biedenkopf, Sarah K. Fehling, My L. Ly, Anne Rechtien, Hans C. Stubbe, Flaminia Olearo, Saskia Borregaard, Alen Jambrecina, Felix Stahl, Thomas Strecker, Markus Eickmann, Marc Lütgehetmann, Michael Spohn, Stefan Schmiedel, Ansgar W. Lohse, Stephan Becker, Marylyn M. Addo, Selidji Todagbe Agnandji, Sanjeev Krishna, Peter G. Kremsner, Jessica S. Brosnahan, Philip Bejon, Patricia Njuguna, Claire-Anne Siegrist, Angela Huttner, Marie-Paule Kieny, Kayvon Modjarrad, Vasee Moorthy, Patricia Fast, Barbara Savarese, Olivier Lapujade
Publikováno v:
EBioMedicine, Vol 19, Iss C, Pp 107-118 (2017)
Background: The recent West African Ebola epidemic led to accelerated efforts to test Ebola vaccine candidates. As part of the World Health Organisation-led VSV Ebola Consortium (VEBCON), we performed a phase I clinical trial investigating rVSV-ZEBOV
Externí odkaz:
https://doaj.org/article/d0ce2f1c3c5144fda4534dfdc5f9b942
Autor:
Rahel Kasonta, Jacqueline Mauritz, Christina Spohr, Carola Sauter-Louis, Karin Duchow, Klaus Cussler, Mark Holsteg, Max Bastian
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Bovine neonatal pancytopenia (BNP) was a vaccine-induced alloimmune disease observed in young calves and characterized by hemorrhages, pancytopenia, and severe destruction of the hematopoietic tissues. BNP was induced by alloreactive maternal antibod
Externí odkaz:
https://doaj.org/article/7e57a28770d04126a37c2a8745fdc3e3
Autor:
Rahel Kasonta, Mark Holsteg, Karin Duchow, James W Dekker, Klaus Cussler, Justin G Bendall, Max Bastian
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109239 (2014)
In 2006, a new haemorrhagic syndrome affecting newborn calves, Bovine Neonatal Pancytopenia (BNP), was reported in southern Germany. It is characterized by severe bleeding, destruction of the red bone marrow, and a high case fatality rate. The syndro
Externí odkaz:
https://doaj.org/article/e68ac231b0c74991aa68206148e1eacf
Autor:
Sabine Yerly, Saskia Borregaard, Benjamin Tsofa, Axel Finckh, Marylyn M. Addo, Laurent Kaiser, Christophe Combescure, Sarah Katharina Fehling, Martin P. Grobusch, Alen Jambrecina, Philip Bejon, Marie-Paule Kieny, Markus Eickmann, Selidji T Agnandji, Nadine Biedenkopf, Michael Ramharter, Patricia Njuguna, Alain Matthey, Domtila Kimani, Rahel Kasonta, Ansgar W. Lohse, Angela Huttner, Emmanuel B. Bache, Patricia E. Fast, Hans Stubbe, Rebekah Burrow, Vasee S. Moorthy, Verena Kraehling, Henry M. Staines, Stefan Schmiedel, Anne Nolting, Gürkan Kaya, A.A. Adegnika, Jessica S Brosnahan, Jay W. Hooper, Marguerite Massinga-Loembe, Thomas Strecker, Sanjeev Krishna, Stephan Becker, Christine Dahlke, José Francisco Fernandes, Sherif R. Zaki, Caroline Ogwang, Floriane Auderset, Benjamin Mordmüller, Peter Silvera, Madeleine E Zinser, Claire-Anne Siegrist, Ana Rita Gonçalves, Jules Alexandre Desmeules, Anita Lumeka Kabwende, Jonas Schmidt-Chanasit, Julie-Anne Dayer, Peter G. Kremsner, Bertrand Lell, Barbara Lemaître, Felix R. Stahl, Marcus Altfeld
Publikováno v:
New England journal of medicine, 374(17), 1647-1660. Massachussetts Medical Society
BACKGROUND: The replication-competent recombinant vesicular stomatitis virus (rVSV)-based vaccine expressing a Zaire ebolavirus (ZEBOV) glycoprotein was selected for rapid safety and immunogenicity testing before its use in West Africa. METHODS: We p
Autor:
Carola Sauter-Louis, Christina Spohr, Max Bastian, Klaus Cussler, Karin Duchow, Rahel Kasonta, Jacqueline Mauritz, M. Holsteg
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology
Bovine neonatal pancytopenia (BNP) was a vaccine-induced alloimmune disease observed in young calves and characterized by hemorrhages, pancytopenia, and severe destruction of the hematopoietic tissues. BNP was induced by alloreactive maternal antibod
Autor:
Hans Stubbe, Michael Spohn, Anne Rechtien, Flaminia Olearo, Christine Dahlke, Vebcon, Stefan Schmiedel, Adam Grundhoff, T. Fischer, Madeleine E Zinser, Ansgar W. Lohse, My L Ly, Marylyn M. Addo, Rahel Kasonta
Publikováno v:
Vaccine. 36(46)
VSV-EBOV is a replication-competent Ebola virus (EBOV) vaccine, which was tested in clinical trials as response to the Ebola virus disease (EVD) outbreak 2013–2016. It is the most advanced EBOV candidate currently in the licensure process. The expe
Autor:
Stephan Becker, My L Ly, Stefan Schmiedel, Rahel Kasonta, Marylyn M. Addo, Sarah Katharina Fehling, Christine Dahlke, Ansgar W. Lohse, Abdourahmane Sow, Benno Kreuels, Marcus Altfeld, Sebastian Lunemann, Thomas Strecker, César Muñoz-Fontela
Publikováno v:
The Journal of infectious diseases. 215(2)
The West African Ebola virus disease (EVD) outbreak was the largest EVD outbreak in history. However, data on lymphocyte dynamics and the antigen specificity of T cells in Ebola survivors are scarce, and our understanding of EVD pathophysiology is li
Publikováno v:
Veterinary Record Case Reports. 2
Bovine neonatal pancytopenia (BNP) is a vaccine-induced alloimmune disease. The syndrome affects young calves and is characterised by haemorrhages, pancytopenia and severe destruction of the haematopoietic tissue. Recent evidence indicates that vacci