Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rahel Fitzel"'
Autor:
Max Schumacher, Sina Beer, Emmanuelle Moraes Ribeiro, Fulya Korkmaz, Hildegard Keppeler, Rahel Fitzel, Estelle Erkner, Pia Radszuweit, Claudia Lengerke, Corina Schneidawind, Sebastian Hoefert, Paul Stefan Mauz, Dominik Schneidawind
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Locally advanced or metastatic head and neck squamous cell carcinoma (HNSCC) is associated with a poor prognosis. The introduction of PD-1 inhibitors has led to a significant improvement in survival, but only a subpopulation of patients responds to t
Externí odkaz:
https://doaj.org/article/d33f19f03c004d94af433713e6586503
Autor:
Rahel Fitzel, Kathy-Ann Secker-Grob, Hildegard Keppeler, Fulya Korkmaz, Rebekka Schairer, Estelle Erkner, Dominik Schneidawind, Claudia Lengerke, Thomas Hentrich, Julia M. Schulze-Hentrich, Corina Schneidawind
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 41, Iss , Pp 100902- (2023)
MLL rearranged (MLLr) leukemias are associated with a poor prognosis and a limited response to conventional therapies. Moreover, chemotherapies result in severe side effects with significant impairment of the immune system. Therefore, the identificat
Externí odkaz:
https://doaj.org/article/5a2bbb231dbd41e0b156cb49a9804d52
Autor:
Jacqueline Fischer, Estelle Erkner, Rahel Fitzel, Pia Radszuweit, Hildegard Keppeler, Fulya Korkmaz, Giovanni Roti, Claudia Lengerke, Dominik Schneidawind, Corina Schneidawind
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14466 (2023)
MLL rearrangement (MLLr) is responsible for the development of acute leukemias with poor outcomes. Therefore, new therapeutic approaches are urgently needed. The NOTCH1 pathway plays a critical role in the pathogenesis of many cancers including acute
Externí odkaz:
https://doaj.org/article/141c8ec1797b428787335dc5fdca4e83
Autor:
Verena J. Herbener, Timo Burster, Alicia Goreth, Maximilian Pruss, Hélène von Bandemer, Tim Baisch, Rahel Fitzel, Markus D. Siegelin, Georg Karpel-Massler, Klaus-Michael Debatin, Mike-Andrew Westhoff, Hannah Strobel
Publikováno v:
Biomedicines, Vol 8, Iss 6, p 151 (2020)
Temozolomide (TMZ) currently remains the only chemotherapeutic component in the approved treatment scheme for Glioblastoma (GB), the most common primary brain tumour with a dismal patient’s survival prognosis of only ~15 months. While frequently de
Externí odkaz:
https://doaj.org/article/0dbaa97e9f6545918629051de32f143c
Autor:
Hannah Strobel, Tim Baisch, Rahel Fitzel, Katharina Schilberg, Markus D. Siegelin, Georg Karpel-Massler, Klaus-Michael Debatin, Mike-Andrew Westhoff
Publikováno v:
Biomedicines, Vol 7, Iss 3, p 69 (2019)
The alkylating agent temozolomide (TMZ) together with maximal safe bulk resection and focal radiotherapy comprises the standard treatment for glioblastoma (GB), a particularly aggressive and lethal primary brain tumor. GB affects 3.2 in 100,000 peopl
Externí odkaz:
https://doaj.org/article/3cafa8d21c9b43a3b1de5c21f052f962
Autor:
John Fehilly, Olivia Carey, Eoghan Thomas O’Leary, Stephen O’Shea, Klaudia Juda, Rahel Fitzel, Pooja Selvaraj, Andrew J. Lindsay, Bálint Mészáros, Kellie Dean
SMAUG1 is a human RNA-binding protein that is known to be dysregulated in a wide range of diseases. It is evolutionarily conserved and has been shown to form condensates containing translationally repressed RNAs. This indicates that condensation is c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f67838b227ac88dd916f208640f1442
https://doi.org/10.1101/2023.02.09.527857
https://doi.org/10.1101/2023.02.09.527857
Autor:
Estelle Erkner, Thomas Hentrich, Rahel Fitzel, Hildegard Keppeler, Fulya Korkmaz, Johan Jeong, Julia Schulze-Hentrich, Claudia Lengerke, Dominik Schneidawind, Corina Schneidawind
Publikováno v:
Blood. 140:2999-3000
Autor:
Pia Radszuweit, Fulya Korkmaz, Barbara Mankel, Rahel Fitzel, Estelle Erkner, Hildegard Keppeler, Claudia Lengerke, Dominik Schneidawind, Corina Schneidawind
Publikováno v:
Blood. 140:5879-5879
Autor:
Rahel Fitzel, Sarah Brüstl, Fulya Korkmaz, Barbara Mankel, Estelle Erkner, Hildegard Keppeler, Claudia Lengerke, Dominik Schneidawind, Corina Schneidawind
Publikováno v:
Blood. 140:5857-5857
Autor:
Emmanuelle Moraes Ribeiro, Rahel Fitzel, Anita Schmitt, Brigitte Neuber, Hildegard Keppeler, Fulya Korkmaz, Claudia Lengerke, Michael Schmitt, Dominik Schneidawind
Publikováno v:
Transplantation and Cellular Therapy. 28:S165-S166