The importance of plasmin for the healing of the anterior cruciate ligament

Autor: Benjamin Gantenbein, Rahel Deborah May, Karin Tschan, Ezgi Bakirci, Barbara Katharina Kleer, Sufian S. Ahmad

Publikováno v: Bone & Joint Research, Vol 9, Iss 9, Pp 543-553 (2020)
Bone & Joint Research
Bakirci, Ezgi; Tschan, Karin; May, Rahel D.; Ahmad, Sufian S; Kleer, Barbara; Gantenbein, Benjamin (2020). The importance of plasmin for the healing of the anterior cruciate ligament. Bone & joint research, 9(9), pp. 543-553. British Editorial Society of Bone & Joint Surgery 10.1302/2046-3758.99.BJR-2020-0048.R1

Aims The anterior cruciate ligament (ACL) is known to have a poor wound healing capacity, whereas other ligaments outside of the knee joint capsule such as the medial collateral ligament (MCL) apparently heal more easily. Plasmin has been identified

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ffdf93f96269937cb98cf2ea57c6de
https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.99.BJR-2020-0048.R1

Differentiation of MSC and annulus fibrosus cells on genetically engineered silk fleece-membrane-composites enriched for GDF-6 or TGF-β3

Autor: Benjamin Gantenbein, Daniela Angelika Frauchiger, Silvan Heeb, Lorin Michael Benneker, Michael Wöltje, Rahel Deborah May

Publikováno v: Journal of Orthopaedic Research®. 36:1324-1333

Intervertebral disc (IVD) repair is a high-priority topic in our active and increasingly ageing society. Since a high number of people are affected by low back pain treatment options that are able to restore the biological function of the IVD are hig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7de525ecbdd59997754a1ded81f0d9c2
https://doi.org/10.1002/jor.23778

Exogenous Stimulation of Human Intervertebral Disc Cells in 3-Dimensional Alginate Bead Culture With BMP2 and L51P: Cytocompatibility and Effects on Cell Phenotype

Autor: Daniela Angelika Frauchiger, Rahel Deborah May, Christoph E. Albers, Benjamin Gantenbein, Willy Hofstetter

Publikováno v: Neurospine
May, Rahel D.; Frauchiger, Daniela A.; Albers, Christoph E.; Hofstetter, Wilhelm; Gantenbein, Benjamin (2020). Exogenous Stimulation of Human Intervertebral Disc Cells in 3-Dimensional Alginate Bead Culture With BMP2 and L51P: Cytocompatibility and Effects on Cell Phenotype. Neurospine, 17(1), pp. 77-87. Korean Spinal Neurosurgery Society 10.14245/ns.2040002.001
Neurospine, Vol 17, Iss 1, Pp 77-87 (2020)

Objective: Spinal fusion surgery is a common treatment modality for various pathologic conditions of the spine. The bone morphogenetic protein 2 (BMP2) analogue L51P acts as a general inhibitor of BMP antagonists, whereas it shows a weak affinity for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de496bf994fdc76ce9a15230ae49d0d
https://pubmed.ncbi.nlm.nih.gov/32252157

Inhibitory Effects of Human Primary Intervertebral Disc Cells on Human Primary Osteoblasts in a Co-Culture System

Autor: Christoph E. Albers, Daniela Angelika Frauchiger, Lorin Michael Benneker, Rahel Deborah May, Sandro Kohl, Benjamin Gantenbein

Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 4, p 1195 (2018)
International Journal of Molecular Sciences
May, Rahel Deborah; Frauchiger, Daniela Angelika; Albers, Christoph; Benneker, Lorin Michael; Kohl, Sandro; Gantenbein, Benjamin (2018). Inhibitory Effects of Human Primary Intervertebral Disc Cells on Human Primary Osteoblasts in a Co-Culture System. International journal of molecular sciences, 19(4) Molecular Diversity Preservation International MDPI 10.3390/ijms19041195
International Journal of Molecular Sciences; Volume 19; Issue 4; Pages: 1195

Spinal fusion is a common surgical procedure to address a range of spinal pathologies, like damaged or degenerated discs. After the removal of the intervertebral disc (IVD), a structural spacer is positioned followed by internal fixation, and fusion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6b91601f45b4ad154eb97560b137bba
http://www.mdpi.com/1422-0067/19/4/1195

Efficient Nonviral Transfection of Primary Intervertebral Disc Cells by Electroporation for Tissue Engineering Application

Autor: Benjamin Gantenbein, Daniela Angelika Frauchiger, Lorin Michael Benneker, Rahel Deborah May, Adel Tekari, Anna Krismer

Low back pain (LBP) is an increasing global health problem associated with intervertebral disc (IVD) trauma and degeneration. Current treatment options include surgical interventions with partial unsatisfactory outcomes reported such as failure to re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dde5aed66be06b54c0b809c274d6f68