Development of a fibrin-targeted theranostic for gastric cancer.

Autor: Esfahani SA; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Ma L; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA., Krishna S; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA., Ma H; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA., Raheem SJ; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Shuvaev S; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA., Rotile NJ; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA., Weigand-Whittier J; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA., Boice AT; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA., Borges N; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Treaba CA; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA., Deffler C; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Diyabalanage H; Collagen Medical LLC, Boston, MA 02116, USA., Humblet V; Collagen Medical LLC, Boston, MA 02116, USA., Sosnovik DE; Cardiovascular Research Center, Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA., Mahmood U; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Heidari P; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Shih A; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Catana C; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA., Strickland MR; Division of Hematology-Oncology, Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Klempner SJ; Division of Hematology-Oncology, Mass General Cancer Center and Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Caravan P; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.; Institute for Innovation in Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA.

Publikováno v: Science translational medicine [Sci Transl Med] 2024 Dec 11; Vol. 16 (777), pp. eadn7218. Date of Electronic Publication: 2024 Dec 11.

DFO-Km: A Modular Chelator as a New Chemical Tool for the Construction of Zirconium-89-Based Radiopharmaceuticals.

Autor: Salih AK; Radiopharmacology, Mariana Oncology, Woburn, Massachusetts 01801, United States., Dominguez Garcia M; Department of Chemistry, College of Arts and Science, University of Saskatchewan, 110 Science Place, Saskatoon, Saskatchewan S7N-5C9, Canada., Raheem SJ; Department of Chemistry, College of Arts and Science, University of Saskatchewan, 110 Science Place, Saskatoon, Saskatchewan S7N-5C9, Canada., Ahiahonu WK; Department of Chemistry, College of Arts and Science, University of Saskatchewan, 110 Science Place, Saskatoon, Saskatchewan S7N-5C9, Canada., Price EW; Department of Chemistry, College of Arts and Science, University of Saskatchewan, 110 Science Place, Saskatoon, Saskatchewan S7N-5C9, Canada.

Publikováno v: Inorganic chemistry [Inorg Chem] 2023 Dec 18; Vol. 62 (50), pp. 20806-20819. Date of Electronic Publication: 2023 Sep 26.

Design, Synthesis, and Evaluation of DFO-Em: A Modular Chelator with Octadentate Chelation for Optimal Zirconium-89 Radiochemistry.

Autor: Salih AK; Department of Chemistry, College of Arts and Science, University of Saskatchewan, 110 Science Place, S7N-5C9Saskatoon, SKCanada., Raheem SJ; Department of Chemistry, College of Arts and Science, University of Saskatchewan, 110 Science Place, S7N-5C9Saskatoon, SKCanada., Garcia MD; Department of Chemistry, College of Arts and Science, University of Saskatchewan, 110 Science Place, S7N-5C9Saskatoon, SKCanada., Ahiahonu WK; Department of Chemistry, College of Arts and Science, University of Saskatchewan, 110 Science Place, S7N-5C9Saskatoon, SKCanada., Price EW; Department of Chemistry, College of Arts and Science, University of Saskatchewan, 110 Science Place, S7N-5C9Saskatoon, SKCanada.

Publikováno v: Inorganic chemistry [Inorg Chem] 2022 Dec 26; Vol. 61 (51), pp. 20964-20976. Date of Electronic Publication: 2022 Dec 14.

A High-Denticity Chelator Based on Desferrioxamine for Enhanced Coordination of Zirconium-89.

Autor: Sarbisheh EK; Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, Saskatchewan S7N 5C9, Canada., Salih AK; Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, Saskatchewan S7N 5C9, Canada., Raheem SJ; Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, Saskatchewan S7N 5C9, Canada., Lewis JS; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.; Radiochemistry and Molecular Imaging Probes Core, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.; Department of Pharmacology, Weill Cornell Medical College, New York, New York 10065, United States.; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.; Department of Radiology, Weill Cornell Medical College, New York, New York 10065, United States., Price EW; Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, Saskatchewan S7N 5C9, Canada.

Publikováno v: Inorganic chemistry [Inorg Chem] 2020 Aug 17; Vol. 59 (16), pp. 11715-11727. Date of Electronic Publication: 2020 Jul 28.