Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Rahaf Issa"'
Autor:
Luke R. Green, Rahaf Issa, Fawzyah Albaldi, Lucy Urwin, Ruth Thompson, Henna Khalid, Claire E. Turner, Barbara Ciani, Lynda J. Partridge, Peter N. Monk
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Epithelial colonization is a critical first step in bacterial pathogenesis. Staphylococcus aureus can utilize several host factors to associate with cells, including α5β1 integrin and heparan sulfate proteoglycans, such as the syndecans. H
Externí odkaz:
https://doaj.org/article/5d075cea95f446b7b507d17006be5322
Human lung organoids (HLOs) are increasingly used to model development and infectious diseases, however their ability to recapitulate functional pulmonary tissue response to nanomaterials (NMs) has yet to be demonstrated. Here, we established a lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5203eb7edb53919a0940f60a27c3d0ed
https://doi.org/10.1101/2023.03.30.534957
https://doi.org/10.1101/2023.03.30.534957
147 Human Lung Organoids Predict Response to Carbon-Based Nanomaterials and Model Pulmonary Fibrosis
Publikováno v:
Annals of Work Exposures and Health. 67:i73-i74
Advances in in-vitro culture systems have stimulated an interest in more reliable testing approaches that predict nanomaterial toxicity. Lung organoids are one example, and display functions consistent with their in-vivo counterparts. Organoids have
Autor:
Kathakali De, Jayanta Haldar, Peter N. Monk, Swagatam Barman, Mohini M. Konai, Utsarga Adhikary, Rahaf Issa, Sheila MacNeil
Publikováno v:
ACS Infectious Diseases. 6:703-714
The role of molecular arrangement of hydrophobic and hydrophilic groups for designing membrane-active molecules remains largely ambiguous. To explore this aspect, herein we report a series of membrane-active small molecules by varying the spatial dis
Publikováno v:
Trends in Microbiology. 27:323-338
As more antibiotics are rendered ineffective by drug-resistant bacteria, focus must be shifted towards alternative therapies for treating infections. Although several alternatives already exist in nature, the challenge is to implement them in clinica
Publikováno v:
Journal of dermatological science. 105(2)
Elevated protease activity is a characteristic feature of chronic wounds, where the inflammatory phase of wound healing is prolonged. The choice of dressings in treatment of chronic wounds can change the nature of the wound base and have a significan
Autor:
Nata Bakuradze, Khatuna Makalatia, Elene Kakabadze, Jon Caplin, Ian Cooper, Rahaf Issa, Nina Chanishvili
Publikováno v:
Journal of Applied Microbiology
Aims This paper presents the potential of environmentally sourced bacteriophages to affect the growth of clinical isolates of Pseudomonas aeruginosa biofilms, and assesses the respective plaque morphotypes presented by each bacteriophage, in vitro. M
Autor:
Roxana Jijie, Sabine Szunerits, N. Dumitrascu, Rahaf Issa, Rabah Boukherroub, Ian Cooper, Peter J. Cragg, Vladimir Zaitsev, Lyuba Mikhalovska, Alexandre Barras, Volodymyr Turcheniuk, Viktoria Raks
Publikováno v:
Diamond and Related Materials. 57:2-8
Advances in nanotechnology have seen the development of several microbiocidal nanoparticles displaying activity against biofilms. These applications benefit from one or more combinations of the nanoparticle properties. Nanoparticles may indeed concen
Autor:
Rabah Boukherroub, Alexandre Barras, Viktoria Raks, Aloysius Siriwardena, José M. García Fernández, Manakamana Khanal, V. O. Chernyshenko, Sabine Szunerits, Vladimir Zaitsev, Volodymyr Turcheniuk, Rahaf Issa, Ian Cooper, Peter J. Cragg, Lyuba Mikhalovska
Publikováno v:
Particle & Particle Systems Characterization. 32:822-830
Diamond nanoparticles (NDs) have demonstrated great promise as useful materials in a variety of biomedical settings. In this paper, the antimicrobial and antibiofi lm activities of variously functionalized NDs against two common bacterial targets Gra
Use of Poly (ε-Lysine) Dendrons: A Strategy Targeting Bacterial Quorum Sensing and Biofilm Formation
Publikováno v:
Conference Papers in Science. 2014:1-8
Pseudomonas aeruginosa is recognised as a major aetiological agent of nosocomial infections, which are associated with multiple-antibiotic resistance. Among many of its important virulence factors is its ability to form biofilms on the surfaces of im