Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ragnberth Helleday"'
Autor:
Jenny A Bosson, Anders Blomberg, Nikolai Stenfors, Ragnberth Helleday, Frank J Kelly, Annelie F Behndig, Ian S Mudway
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81816 (2013)
BackgroundOzone concentrations are predicted to increase over the next 50 years due to global warming and the increased release of precursor chemicals. It is therefore urgent that good, reliable biomarkers are available to quantify the toxicity of th
Externí odkaz:
https://doaj.org/article/5e8594836e68471ca7732787ec1b37cc
Autor:
Thomas Sandström, Nirina Larsson, Ragnberth Helleday, Sean T Duggan, Annelie F. Behndig, Susan J. Wilson, Ian Mudway, Joanna L Brown, Anders Blomberg, Frank J. Kelly, Nikolai Stenfors, Rosamund Dove
Publikováno v:
Thorax. 66:12-19
Exposure to traffic-derived air pollutants, particularly diesel emissions, has been associated with adverse health effects, predominantly in individuals with pre-existing respiratory disease. Here the hypothesis that this heightened sensitivity refle
Autor:
Anthony J. Frew, Annelie F. Behndig, Nikolai Stenfors, Anders Blomberg, Ragnberth Helleday, Ian Mudway, Frank J. Kelly, Jenny A. Bosson, Jamshid Pourazar, Håkan Törnqvist, Thomas Sandström
Publikováno v:
Inhalation Toxicology. 22:133-139
Asthmatics are recognised to be more susceptible than healthy individuals to adverse health effects caused by exposure to the common air pollutant ozone. Ozone has been reported to induce airway neutrophilia in mild asthmatics, but little is known ab
Autor:
Sean T Duggan, Anders Blomberg, Ian Mudway, Annelie F. Behndig, Frank J. Kelly, Ragnberth Helleday
Publikováno v:
Inhalation Toxicology. 21:933-942
The aim of the study was to characterize ozone-induced antioxidant responses in the human airway, including the resident leukocyte population, bronchial mucosa, and respiratory-tract lining fluids. Fifteen healthy subjects were exposed to 0.2 ppm ozo
Autor:
Anthony J. Frew, Susan J. Wilson, James M. Samet, Thomas Sandström, Ian Mudway, Jamshid Pourazar, Anders Blomberg, Ragnberth Helleday, Frank J. Kelly
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 289:L724-L730
Diesel exhaust (DE) is a major component of airborne particulate matter. In previous studies we have described the acute inflammatory response of the human airway to inhaled DE. This was characterized by neutrophil, mast cell, and lymphocyte infiltra
Autor:
Nikolai Stenfors, Anders Blomberg, A. J. Frew, Susan J. Wilson, Thomas Sandström, Frank J. Kelly, Stephen T. Holgate, Jenny A. Bosson, Jamshid Pourazar, Ragnberth Helleday, Anders Bucht
Publikováno v:
Clinical & Experimental Allergy. 33:777-782
Background Ozone (O3) is a common air pollutant associated with adverse health effects. Asthmatics have been suggested to be a particularly sensitive group. Objective This study evaluated whether b ...
Publikováno v:
Revue Française d'Allergologie et d'Immunologie Clinique. 40:47-51
Summary This review has been directed to describe the present state of experimental animal studies investigating the effects of automobile associated air pollution on allergen sensitization and responsiveness. There is mounting evidence from a large
Publikováno v:
European Respiratory Journal. 7:1213-1220
We have previously reported on the bronchoalveolar inflammatory effects of the common air pollutant NO2 in nonsmokers. In this study, we have investigated these effects in tobacco smokers. Eight young nonbronchitic smokers and, as a reference group,
Publikováno v:
Inhalation toxicology. 21(3)
Low molecular weight antioxidants within human respiratory tract lining fluids (RTLFs) have been proposed to confer protection against the damaging action of inhaled oxidant gases. There is therefore considerable interest in augmenting the concentrat
Autor:
Bo Segerstedt, Anders Blomberg, Gunnar F. Nordberg, Ian Mudway, Ragnberth Helleday, Alfred Bernard, Bertil Forsberg
Publikováno v:
Chest. 130(3)
We have previously demonstrated Clara cell protein (CC16) [secretoglobin 1A1] in serum to be a highly sensitive biomarker of altered lung epithelial permeability after ozone challenge. As a previous experimental study has indicated a diurnal variatio