Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Ragna Sannerud"'
Autor:
Zoë P. Van Acker, Anika Perdok, Ruben Hellemans, Katherine North, Inge Vorsters, Cedric Cappel, Jonas Dehairs, Johannes V. Swinnen, Ragna Sannerud, Marine Bretou, Markus Damme, Wim Annaert
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Phospholipase D3 (PLD3) polymorphisms are linked to late-onset Alzheimer’s disease (LOAD). Being a lysosomal 5’-3’ exonuclease, its neuronal substrates remained unknown as well as how a defective lysosomal nucleotide catabolism connect
Externí odkaz:
https://doaj.org/article/293aabf59d5247c19a7f1c12925e6771
Autor:
Abril Angélica Escamilla-Ayala, Ragna Sannerud, Magali Mondin, Karin Poersch, Wendy Vermeire, Laura Paparelli, Caroline Berlage, Marcelle Koenig, Lucia Chavez-Gutierrez, Maximilian H Ulbrich, Sebastian Munck, Hideaki Mizuno, Wim Annaert
Publikováno v:
eLife, Vol 9 (2020)
γ-Secretase is a multi-subunit enzyme whose aberrant activity is associated with Alzheimer’s disease and cancer. While its structure is atomically resolved, γ-secretase localization in the membrane in situ relies mostly on biochemical data. Here,
Externí odkaz:
https://doaj.org/article/a670ba027c4a475a924b0ed9c1d6e874
Autor:
Laura Paparelli, Nikky Corthout, Benjamin Pavie, Devin L Wakefield, Ragna Sannerud, Tijana Jovanovic-Talisman, Wim Annaert, Sebastian Munck
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 9, p e1005095 (2016)
Cell surface protein and lipid molecules are organized in various patterns: randomly, along gradients, or clustered when segregated into discrete micro- and nano-domains. Their distribution is tightly coupled to events such as polarization, endocytos
Externí odkaz:
https://doaj.org/article/03f9975abff148eda93e9a50bbddc1a2
Publikováno v:
Alzheimer's & Dementia. 18
Publikováno v:
Alzheimer's & Dementia. 18
Publikováno v:
Alzheimer's & Dementia. 17
Autor:
Wim Annaert, Katleen Dillen, Randy Schekman, Ragna Sannerud, Bertrand Kleizen, Rosanne Wouters, David Demedts, Christine Michiels, Abril Escamilla Ayala, Wendy Vermeire
Publikováno v:
Journal of Cell Biology, 220(9), 1. Rockefeller University Press
γ-Secretase affects many physiological processes through targeting >100 substrates; malfunctioning links γ-secretase to cancer and Alzheimer's disease. The spatiotemporal regulation of its stoichiometric assembly remains unresolved. Fractionation,
Autor:
Norin Nabil Hamouda, Steven H. L. Verhelst, Mujahid Azfar, Chris Van den Haute, Jan Eggermont, Patrizia Agostinis, Álvaro Cortés Calabuig, Rupert L. Mayer, Ragna Sannerud, Veerle Baekelandt, Johannes V. Swinnen, Francis Impens, Roeland Vanhoutte, Shaun Martin, Wim Annaert, Peter Vangheluwe
Publikováno v:
JOURNAL OF BIOLOGICAL CHEMISTRY
The Journal of Biological Chemistry
The Journal of Biological Chemistry
Polyamines, such as putrescine, spermidine, and spermine, are physiologically important polycations, but the transporters responsible for their uptake in mammalian cells remain poorly characterized. Here, we reveal a new component of the mammalian po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3668301cd9df2fa08723616ddfa1c32
https://lirias.kuleuven.be/handle/123456789/665088
https://lirias.kuleuven.be/handle/123456789/665088
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Wim Annaert, Bertrand Kleizen, Randy Schekman, Ragna Sannerud, Katleen Dillen, David Demedts, Rosanne Wouters, Christine Michiels, Wendy Vermeire
Publikováno v:
Alzheimer's & Dementia. 16