Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ragna S, Boerma"'
Autor:
Ragna S Boerma, T Sonia Boender, Kim C.E. Sigaloff, Tobias F Rinke de Wit, Michael Boele vanHensbroek, Nicaise Ndembi, Titilope Adeyemo, Edamisan O Temiye, Akin Osibogun, Pascale Ondoa, Job C Calis, Alani Sulaimon Akanmu
Publikováno v:
Journal of the International AIDS Society, Vol 19, Iss 1, Pp n/a-n/a (2016)
Introduction Pre‐treatment HIV drug resistance (PDR) is an increasing problem in sub‐Saharan Africa. Children are an especially vulnerable population to develop PDR given that paediatric second‐line treatment options are limited. Although monit
Externí odkaz:
https://doaj.org/article/c37e572d41f942fdb6fd5609f62a39a4
Reaching 90-90-90: outcomes of a 15-year multi-country HIV workplace programme in sub-Saharan Africa
Autor:
Henk Rijckborst, Stefaan van der Borght, Patrick Chukwumah, Onno P. Schellekens, Ferdinand W. N. M. Wit, Herbert Schilthuis, Tobias F. Rinke de Wit, Ragna S. Boerma
Publikováno v:
Antiviral therapy, 24(5), 363-370. International Medical Press Ltd
Background In 2001, an international beverage company implemented an HIV workplace programme providing free antiretroviral treatment (ART) for employees and dependents in sub-Saharan Africa, at a time when ART, cost assessments of ART programmes and
Autor:
M Boele van Hensbroek, R Nakanjako, Peter Mugyenyi, K C E Sigaloff, Minke H. W. Huibers, Job C. J. Calis, Silvia Bertagnolio, T. F. Rinke de Wit, Sheila Balinda, Elizabeth Kaudha, Ragna S. Boerma, Cissy Kityo
Publikováno v:
The Journal of antimicrobial chemotherapy, 74(10), 3035-3043
Journal of antimicrobial chemotherapy, 74(10), 3035-3043. Oxford University Press
Huibers, M H W, Kityo, C, Boerma, R S, Kaudha, E, Sigaloff, K C E, Balinda, S N, Bertagnolio, S, Nakanjako, R, Mugyenyi, P, Calis, J C J, Boele van Hensbroek, M & Rinke de Wit, T F 2019, ' Long-term virological outcomes, failure and acquired resistance in a large cohort of Ugandan children ', The Journal of antimicrobial chemotherapy, vol. 74, no. 10, pp. 3035-3043 . https://doi.org/10.1093/jac/dkz266
Journal of antimicrobial chemotherapy, 74(10), 3035-3043. Oxford University Press
Huibers, M H W, Kityo, C, Boerma, R S, Kaudha, E, Sigaloff, K C E, Balinda, S N, Bertagnolio, S, Nakanjako, R, Mugyenyi, P, Calis, J C J, Boele van Hensbroek, M & Rinke de Wit, T F 2019, ' Long-term virological outcomes, failure and acquired resistance in a large cohort of Ugandan children ', The Journal of antimicrobial chemotherapy, vol. 74, no. 10, pp. 3035-3043 . https://doi.org/10.1093/jac/dkz266
Objectives To evaluate long-term virological failure (VF) and drug resistance among HIV-infected Ugandan children on first-line ART. Methods In a multicentre prospective cohort study, viral load (VL) and drug resistance mutations (DRMs) were investig
Autor:
Clement Zeh, Ragna S. Boerma, Kim C. E. Sigaloff, Peter Mugyenyi, Job C. J. Calis, Tobias F. Rinke de Wit, Sulaimon Akanmu, Raph L. Hamers, Seth C Inzaule
Publikováno v:
AIDS, 143-147
STARTPAGE=143;ENDPAGE=147;TITLE=AIDS
AIDS (London, England), 32(2), 143-147. Lippincott Williams and Wilkins
Inzaule, S C, Hamers, R L, Calis, J, Boerma, R, Sigaloff, K, Zeh, C, Mugyenyi, P, Akanmu, S & Rinke De Wit, T F 2018, When prevention of mother-To-child HIV transmission fails: Preventing pretreatment drug resistance in African children . in AIDS . AIDS, vol. 32, pp. 143-147 . https://doi.org/10.1097/QAD.0000000000001696
STARTPAGE=143;ENDPAGE=147;TITLE=AIDS
AIDS (London, England), 32(2), 143-147. Lippincott Williams and Wilkins
Inzaule, S C, Hamers, R L, Calis, J, Boerma, R, Sigaloff, K, Zeh, C, Mugyenyi, P, Akanmu, S & Rinke De Wit, T F 2018, When prevention of mother-To-child HIV transmission fails: Preventing pretreatment drug resistance in African children . in AIDS . AIDS, vol. 32, pp. 143-147 . https://doi.org/10.1097/QAD.0000000000001696
The scale-up of antiretroviral prophylaxis to prevent mother-to-child transmission of HIV has significantly reduced new pediatric infections in sub-Saharan Africa. However, among infants who become HIV-infected despite prevent mother-to-child transmi
Autor:
Ragna S, Boerma, Kees P, Braun, Marcel P H, van den Broek, Maarten P H, van de Broek, Frederique M C, van Berkestijn, Marielle E, Swinkels, Eveline O, Hagebeuk, Dick, Lindhout, Marjan, van Kempen, Maartje, Boon, Joost, Nicolai, Carolien G, de Kovel, Eva H, Brilstra, Bobby P C, Koeleman
Publikováno v:
Neurotherapeutics
Neurotherapeutics, 13(1), 192. Springer New York
Neurotherapeutics, 13(1), 192-197. SPRINGER
Neurotherapeutics, 13(1), 192-197. Springer Verlag
Neurotherapeutics, 13(1), 192. Springer New York
Neurotherapeutics, 13(1), 192-197. SPRINGER
Neurotherapeutics, 13(1), 192-197. Springer Verlag
Mutations in SCN8A are associated with epilepsy and intellectual disability. SCN8A encodes for sodium channel Nav1.6, which is located in the brain. Gain-of-function missense mutations in SCN8A are thought to lead to increased firing of excitatory ne
Autor:
Dara A. Lehman, Torsak Bunupuradah, Sam Sophan, Kim C. E. Sigaloff, Victor Musiime, Joseph Fokam, Ragna S. Boerma, Annelot F Schoffelen, Paul Palumbo, Cissy Kityo, Brian C. Zanoni, Tobias F. Rinke de Wit, Dorothy E. Dow, Azar Kariminia, Job C. J. Calis
Publikováno v:
Journal of the International AIDS Society
Journal of the international aids society, 20(1):1930. International AIDS Society
Boerma, R S, Bunupuradah, T, Dow, D, Fokam, J, Kariminia, A, Lehman, D, Kityo, C, Musiime, V, Palumbo, P, Schoffelen, A, Sophan, S, Zanoni, B, Rinke De Wit, T F, Calis, J C J & Sigaloff, K C E 2017, ' Multicentre analysis of second-line antiretroviral treatment in HIV-infected children : Adolescents at high risk of failure ', Journal of the international aids society, vol. 20, no. 1, 1930 . https://doi.org/10.7448/IAS.20.1.21930
Journal of the International AIDS Society, 20(1). International AIDS Society
Journal of the international aids society, 20(1):1930. International AIDS Society
Boerma, R S, Bunupuradah, T, Dow, D, Fokam, J, Kariminia, A, Lehman, D, Kityo, C, Musiime, V, Palumbo, P, Schoffelen, A, Sophan, S, Zanoni, B, Rinke De Wit, T F, Calis, J C J & Sigaloff, K C E 2017, ' Multicentre analysis of second-line antiretroviral treatment in HIV-infected children : Adolescents at high risk of failure ', Journal of the international aids society, vol. 20, no. 1, 1930 . https://doi.org/10.7448/IAS.20.1.21930
Journal of the International AIDS Society, 20(1). International AIDS Society
Introduction: The number of HIV-infected children and adolescents requiring second-line antiretroviral treatment (ART) is increasing in low- and middle-income countries (LMIC). However, the effectiveness of paediatric second-line ART and potential ri
Autor:
Elizabeth Kaudha, Victor Musiime, Rita Nakanjako, Kim C. E. Sigaloff, Job C. J. Calis, Sheila Balinda, Cissy Kityo, Peter Mugyenyi, Ragna S. Boerma, T. Sonia Boender, Tobias F. Rinke de Wit
Publikováno v:
Kityo, C, Boerma, R S, Sigaloff, K C E, Kaudha, E, Calis, J C J, Musiime, V, Balinda, S, Nakanjako, R, Boender, T S, Mugyenyi, P N & Rinke de Wit, T F 2017, ' Pretreatment HIV drug resistance results in virological failure and accumulation of additional resistance mutations in Ugandan children ', Journal of Antimicrobial Chemotherapy, vol. 72, no. 9, pp. 2587-2595 . https://doi.org/10.1093/jac/dkx188
Journal of Antimicrobial Chemotherapy, 72(9), 2587-2595. Oxford University Press
Journal of Antimicrobial Chemotherapy
Journal of antimicrobial chemotherapy, 72(9), 2587-2595. Oxford University Press
Journal of Antimicrobial Chemotherapy, 72(9), 2587-2595. Oxford University Press
Journal of Antimicrobial Chemotherapy
Journal of antimicrobial chemotherapy, 72(9), 2587-2595. Oxford University Press
Background: Pretreatment HIV drug resistance (PDR) can impair virological response to ART, jeopardizing effective treatment for children. Methods: Children aged ≤12 years initiated first-line ART in Uganda during 2010-11. Baseline and 6 monthly vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef3de170dfe2c5ee2152cb0392ebd3f8
https://research.vumc.nl/en/publications/a6c33335-b9ac-4171-8988-ff31d5a4d361
https://research.vumc.nl/en/publications/a6c33335-b9ac-4171-8988-ff31d5a4d361
Autor:
Kim Steegen, Kim C. E. Sigaloff, T. Sonia Boender, Mariette E. Botes, Pascale Ondoa, Tobias F. Rinke de Wit, Maureen Wellington, Raph L. Hamers, Immaculate Nankya, Margaret Siwale, Ragna S. Boerma, Job C. J. Calis, Alani S Akanmu, Cissy Kityo, Elizabeth Kaudha
Publikováno v:
Journal of antimicrobial chemotherapy, 71(10), 2918-2927. Oxford University Press
Journal of Antimicrobial Chemotherapy, 71(10):dkw218, 2918-2927. Oxford University Press
Boender, T S, Kityo, C M, Boerma, R S, Hamers, R L, Ondoa, P, Wellington, M, Siwale, M, Nankya, I, Kaudha, E, Akanmu, A S, Botes, M E, Steegen, K, Calis, J C J, Rinke de Wit, T F & Sigaloff, K C E 2016, ' Accumulation of HIV-1 drug resistance after continued virological failure on first-line ART in adults and children in sub-Saharan Africa ', Journal of Antimicrobial Chemotherapy, vol. 71, no. 10, dkw218, pp. 2918-2927 . https://doi.org/10.1093/jac/dkw218
Journal of Antimicrobial Chemotherapy, 71(10):dkw218, 2918-2927. Oxford University Press
Boender, T S, Kityo, C M, Boerma, R S, Hamers, R L, Ondoa, P, Wellington, M, Siwale, M, Nankya, I, Kaudha, E, Akanmu, A S, Botes, M E, Steegen, K, Calis, J C J, Rinke de Wit, T F & Sigaloff, K C E 2016, ' Accumulation of HIV-1 drug resistance after continued virological failure on first-line ART in adults and children in sub-Saharan Africa ', Journal of Antimicrobial Chemotherapy, vol. 71, no. 10, dkw218, pp. 2918-2927 . https://doi.org/10.1093/jac/dkw218
Objectives Limited availability of viral load (VL) monitoring in HIV treatment programmes in sub-Saharan Africa can delay switching to second-line ART, leading to the accumulation of drug resistance mutations (DRMs). The objective of this study was t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940b7cdf36598aa86e3c6b206c24ada4
https://doi.org/10.1093/jac/dkw218
https://doi.org/10.1093/jac/dkw218
Autor:
Seth C Inzaule, Job C. J. Calis, T. F. Rinke de Wit, Ragna S. Boerma, M Boele van Hensbroek, Alani S Akanmu, Kim C. E. Sigaloff
Publikováno v:
Boerma, R S, Sigaloff, K C E, Akanmu, A S, Inzaule, S, van Hensbroek, M B, de Wit, T F R & Calis, J C 2017, ' Alarming increase in pretreatment HIV drug resistance in children living in sub-Saharan Africa : A systematic review and meta-analysis ', Journal of Antimicrobial Chemotherapy, vol. 72, no. 2, pp. 365-371 . https://doi.org/10.1093/jac/dkw463
Journal of Antimicrobial Chemotherapy, 72(2), 365-371. Oxford University Press
Journal of Antimicrobial Chemotherapy, 72(2), 365-371. Oxford University Press
Background: Children have an augmented risk of pretreatment HIV drug resistance (PDR) due to exposure to antiretroviral drugs for the prevention of mother-to-child transmission (PMTCT). Paediatric data are essential to evaluate the effectiveness of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e0ab184ba3ea1a4c8bb7cab8546026b
https://research.vumc.nl/en/publications/2017c625-ae1e-4fe9-b679-85355a3a3863
https://research.vumc.nl/en/publications/2017c625-ae1e-4fe9-b679-85355a3a3863
Autor:
Affuenti Bakia, Michael Boele van Hensbroek, Caroline M. Hartdorff, Sammy Oben Orock, Dieneke Schonenberg-Meinema, Ragna S. Boerma, Ferdinand W. N. M. Wit
Publikováno v:
Boerma, R S, Wit, F W N M, Orock, S O, Schonenberg-Meinema, D, Hartdorff, C M, Bakia, A & van Hensbroek, M B 2015, ' Mortality risk factors among HIV-exposed infants in rural and urban Cameroon ', Tropical Medicine and International Health, vol. 20, no. 2, pp. 170-176 . https://doi.org/10.1111/tmi.12424
Tropical medicine & international health, 20(2), 170-176. Wiley-Blackwell
Tropical Medicine and International Health, 20(2), 170-176. Wiley-Blackwell
Tropical medicine & international health, 20(2), 170-176. Wiley-Blackwell
Tropical Medicine and International Health, 20(2), 170-176. Wiley-Blackwell
Objectives HIV-exposed infants including those who do not become infected have higher morbidity and mortality rates than HIV unexposed infants. The underlying mechanisms of this difference are largely unknown. The objective of this study was to ident