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Akademický článek

Integrated Machine Learning and Chemoinformatics-Based Screening of Mycotic Compounds against Kinesin Spindle ProteinEg5 for Lung Cancer Therapy

Autor: Priyanka Maiti, Priyanka Sharma, Mahesha Nand, Indra D. Bhatt, Muthannan Andavar Ramakrishnan, Shalini Mathpal, Tushar Joshi, Ragini Pant, Shafi Mahmud, Jesus Simal-Gandara, Sultan Alshehri, Mohammed M. Ghoneim, Maha Alruwaily, Ahmed Abdullah Al Awadh, Mohammed Merae Alshahrani, Subhash Chandra

Publikováno v: Molecules, Vol 27, Iss 5, p 1639 (2022)

Among the various types of cancer, lung cancer is the second most-diagnosed cancer worldwide. The kinesin spindle protein, Eg5, is a vital protein behind bipolar mitotic spindle establishment and maintenance during mitosis. Eg5 has been reported to c

Externí odkaz: https://doaj.org/article/67edef1b92e64ca888667c58a5958980

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Identification of potent Antigen 85C inhibitors of Mycobacterium tuberculosis via in-house lichen library and binding free energy studies Part-II

Autor: Tushar Joshi, Amit Joshi, Ragini Pant, Priyanka Maiti, Mahesha Nand, Subhash Chandra, Tanuja Joshi, Veena Pande

Publikováno v: Journal of molecular graphicsmodelling. 103

Tuberculosis remains the cause of mortality throughout the world. Currently, the available anti-tubercular drugs are not effective because of the existence of Multi-Drug resistant tuberculosis (MDR-TB) and Extensively-Drug resistant tuberculosis (XDR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d6a4db34ceedb53d08bf08e69689d6
https://pubmed.ncbi.nlm.nih.gov/33333421

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Identification of potential Mycolyltransferase Ag85C inhibitors of Mycobacterium tuberculosis H37Rv via Virtual High Throughput Screening and Binding free energy studies

Autor: Subhash Chandra, Ragini Pant, Amit Joshi, Priyanka Maiti, Veena Pande, Mahesha Nand

Publikováno v: Journal of molecular graphicsmodelling. 98

Tuberculosis (TB) is a deadly disease which causes millions of death annually worldwide. Although TB is treatable but the rise of cases of multidrug-resistant and totally drug-resistant strains of Mycobacterium tuberculosis (Mtb) poses a great challe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d629eb6a98e61e78e95ef015923f45c5
https://pubmed.ncbi.nlm.nih.gov/32200279

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Virtual screening of natural compounds as inhibitors of EGFR 696-1022 T790M associated with non-small cell lung cancer

Autor: Veena Pande, Subhash Chandra, Madhulata Kumari, Mahesha Nand, Ragini Pant, Priyanka Maiti

Publikováno v: Bioinformation

Non-small cell lung cancer (NSCLC) is the most dominating and lethal type of lung cancer triggering more than 1.3 million deaths per year. The most effective line of treatment against NSCLC is to target epidermal growth factor receptor (EGFR) activat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4283f08a303e20fd6be878c52f34f0
https://doi.org/10.6026/97320630012311

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