Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Raghupathy, Vengoji"'
Autor:
Shakeel Mir, Briana D. Ormsbee Golden, Brandon J. Griess, Raghupathy Vengoji, Eric Tom, Elizabeth A. Kosmacek, Rebecca E. Oberley-Deegan, Geoffrey A. Talmon, Vimla Band, Melissa LT. Teoh-Fitzgerald
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-19 (2022)
Abstract Background A pro-oxidant enzyme, NADPH oxidase 4 (Nox4) has been reported to be a critical downstream effector of TGFβ-induced myofibroblast transformation during fibrosis. While there are a small number of studies suggesting an oncogenic r
Externí odkaz:
https://doaj.org/article/0efaa35fefb54dbf9ab0273a80bfaa76
Autor:
Sanchita Rauth, Koelina Ganguly, Pranita Atri, Seema Parte, Rama Krishna Nimmakayala, Venkatesh Varadharaj, Palanisamy Nallasamy, Raghupathy Vengoji, Ayoola O. Ogunleye, Imayavaramban Lakshmanan, Ramakanth Chirravuri, Mika Bessho, Jesse L. Cox, Jason M. Foster, Geoffrey A. Talmon, Tadayoshi Bessho, Apar Kishor Ganti, Surinder K. Batra, Moorthy P. Ponnusamy
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112043- (2023)
Summary: Cisplatin- and gemcitabine-based chemotherapeutics represent a mainstay of cancer therapy for most solid tumors; however, resistance limits their curative potential. Here, we identify RNA polymerase II-associated factor 1 (PAF1) as a common
Externí odkaz:
https://doaj.org/article/54869e1709fb4e06a58c522c9efae474
Autor:
Jawed Akhtar Siddiqui, Parthasarathy Seshacharyulu, Sakthivel Muniyan, Ramesh Pothuraju, Parvez Khan, Raghupathy Vengoji, Sanjib Chaudhary, Shailendra Kumar Maurya, Subodh Mukund Lele, Maneesh Jain, Kaustubh Datta, Mohd Wasim Nasser, Surinder Kumar Batra
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Bone metastases occur in patients with advanced-stage prostate cancer (PCa). The cell-cell interaction between PCa and the bone microenvironment forms a vicious cycle that modulates the bone microenvironment, increases bone deformities, and
Externí odkaz:
https://doaj.org/article/66ee524372bc4b95b2b7a2c41afe3342
Autor:
Naveenkumar Perumal, Ranjana K. Kanchan, David Doss, Noah Bastola, Pranita Atri, Ramakanth Chirravuri-Venkata, Ishwor Thapa, Raghupathy Vengoji, Shailendra K. Maurya, David Klinkebiel, Geoffrey A. Talmon, Mohd W. Nasser, Surinder K. Batra, Sidharth Mahapatra
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-19 (2021)
Abstract Haploinsufficiency of chromosome 17p and c-Myc amplification distinguish group 3 medulloblastomas which are associated with early metastasis, rapid recurrence, and swift mortality. Tumor suppressor genes on this locus have not been adequatel
Externí odkaz:
https://doaj.org/article/69e1273dd0ee4e588d50bef0ffca43ce
Autor:
Raghupathy Vengoji, Pranita Atri, Muzafar A. Macha, Parthasarathy Seshacharyulu, Naveenkumar Perumal, Kavita Mallya, Yutong Liu, Lynette M. Smith, Satyanarayana Rachagani, Sidharth Mahapatra, Moorthy P. Ponnusamy, Maneesh Jain, Surinder K. Batra, Nicole Shonka
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)
Abstract Background Glioblastoma (GBM) has a devastating median survival of only one year. Treatment includes resection, radiation therapy, and temozolomide (TMZ); however, the latter increased median survival by only 2.5 months in the pivotal study.
Externí odkaz:
https://doaj.org/article/4e0ce5e978e945f986e962d8700e2ec6
Autor:
Imayavaramban Lakshmanan, Sanjib Chaudhary, Raghupathy Vengoji, Parthasarathy Seshacharyulu, Satyanarayana Rachagani, Joseph Carmicheal, Rahat Jahan, Pranita Atri, Ramakanth Chirravuri‐Venkata, Rohitesh Gupta, Saravanakumar Marimuthu, Naveenkumar Perumal, Sanchita Rauth, Sukhwinder Kaur, Kavita Mallya, Lynette M. Smith, Subodh M. Lele, Moorthy P. Ponnusamy, Mohd W. Nasser, Ravi Salgia, Surinder K. Batra, Apar Kishor Ganti
Publikováno v:
Molecular Oncology, Vol 15, Iss 7, Pp 1866-1881 (2021)
Lung cancer (LC) is the leading cause of cancer‐related mortality. However, the molecular mechanisms associated with the development of metastasis are poorly understood. Understanding the biology of LC metastasis is critical to unveil the molecular
Externí odkaz:
https://doaj.org/article/79cbd717b199455f95a62235380b7911
Autor:
Parthasarathy Seshacharyulu, Sushanta Halder, Ramakrishna Nimmakayala, Satyanarayana Rachagani, Sanjib Chaudhary, Pranita Atri, Ramakanth Chirravuri-Venkata, Michel M. Ouellette, Joseph Carmicheal, Shailendra K. Gautam, Raghupathy Vengoji, Shuo Wang, Sicong Li, Lynette Smith, Geoffrey A. Talmon, Kelsey Klute, Quan Ly, Bradley N Reames, Jean L Grem, Lyudmyla Berim, James C Padussis, Sukhwinder Kaur, Sushil Kumar, Moorthy P. Ponnusamy, Maneesh Jain, Chi Lin, Surinder K Batra
Publikováno v:
EBioMedicine, Vol 75, Iss , Pp 103772- (2022)
Summary: Background: Radiation therapy (RT) has a suboptimal effect in patients with pancreatic ductal adenocarcinoma (PDAC) due to intrinsic and acquired radioresistance (RR). Comprehensive bioinformatics and microarray analysis revealed that choles
Externí odkaz:
https://doaj.org/article/391f86e6510b4029a18fb205640acaf2
Autor:
Raghupathy Vengoji, Muzafar A. Macha, Rama Krishna Nimmakayala, Satyanarayana Rachagani, Jawed A. Siddiqui, Kavita Mallya, Santhi Gorantla, Maneesh Jain, Moorthy P. Ponnusamy, Surinder K. Batra, Nicole Shonka
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-13 (2019)
Abstract Background Glioblastoma (GBM) is an aggressive brain tumor with universal recurrence and poor prognosis. The recurrence is largely driven by chemoradiation resistant cancer stem cells (CSCs). Epidermal growth factor receptor (EGFR) and its m
Externí odkaz:
https://doaj.org/article/00e5ea5617f04ca8bff2f16fb4dd63f2
Autor:
Kavita Mallya, Dhanya Haridas, Parthasarathy Seshacharyulu, Ramesh Pothuraju, Wade M. Junker, Shiv Ram Krishn, Sakthivel Muniyan, Raghupathy Vengoji, Surinder K. Batra, Satyanarayana Rachagani
Publikováno v:
Biology Open, Vol 9, Iss 9 (2020)
Pancreatic cancer (PC) is acquired postnatally; to mimic this scenario, we developed an inducible KrasG12D; Ptf1a-CreER™ (iKC) mouse model, in which Kras is activated postnatally at week 16 upon tamoxifen (TAM) administration. Upon TAM treatment, i
Externí odkaz:
https://doaj.org/article/65294a45226d488aa2a5d7ecd2ef03e4
Autor:
Surinder K. Batra, Moorthy P. Ponnusamy, Mokenge P. Malafa, Kavita Mallya, Satyanarayana Rachagani, Subodh M. Lele, Raghupathy Vengoji, Palanisamy Nallasamy, Saravanakumar Marimuthu, Ramakanth Chirravuri Venkata, Sanchita Rauth, Rama Krishna Nimmakayala
Analysis of FAO-OCR using extracellular flux analyzer and Seahorse XF-Palmitate-BSA FAO substrate kit in KC6141 (KC control) cells in the presence and absence of doxycycline.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6fab6040331136a47588c4eb8fa06ec
https://doi.org/10.1158/1078-0432.22481703.v1
https://doi.org/10.1158/1078-0432.22481703.v1
