Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Raghunadha Reddy Burri"'
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112983 (2014)
The viral protein U (Vpu) encoded by HIV-1 has been shown to assist in the detachment of virion particles from infected cells. Vpu forms cation-specific ion channels in host cells, and has been proposed as a potential drug target. An understanding of
Externí odkaz:
https://doaj.org/article/1fd7c35dbc2a4b56bea1b12c1800a876
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 38:3972-3989
Alzheimer's disease (AD), a most prevailing neurodegenerative disorder with turbulence in cognitive and behavioural abilities, epitomizes one of the highest unmet medical requirements. The current AD treatment focuses merely on symptomatic relief, th
Autor:
Nisha K. Anchan, Thomas Langer, Vishal Subhash Mane, Raghunadha Reddy Burri, Christine Rudolph, Herman Schreuder, Joerg Czech, Ramachandraiah Gosu, Rajendra Kristam, Saravanakumar Dhakshinamoorthy, Ramesh Mullangi, Juluri Suresh, Mahanandeesha S. Hallur, Sridharan Rajagopal, Takeshi Yura, Manvi Singh, Aimo Kannt, Devaraj Venkatapura Chandrasekar, Shama Shaik, Sanjay Venkatachalapathi Kadnur, V.P. Rama Kishore Putta, Lokesh Kananti Narasimhulu, Karthikai Raj Murugesan, Ravi Kanth Bhamidipati, Sven Ruf, Indu N. Swamy, Alexander Marker, Sayantani Sarkar
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:922-925
Nicotinamide N-methyltransferase (NNMT) has been linked to obesity and diabetes. We have identified a novel nicotinamide (NA) analog, compound 12 that inhibited NNMT enzymatic activity and reduced the formation of 1-methyl-nicotinamide (MNA), the pri
Autor:
Srinivasan Swaminathan, Rajendra Kristam, Manish Kumar Thakur, Anja Pfenninger, Vishal Subhash Mane, Saravanakumar Dhakshinamoorthy, Ralf Elvert, Saravanan Kandan, Niranjan Naranapura Anand, Takeshi Yura, Reejuana Parveen, Ravi Kanth Bhamidipati, Devaraj Venkatapura Chandrasekar, Ramesh Mullangi, Sridharan Rajagopal, Raghunadha Reddy Burri, Herman Schreuder, Mahanandeesha S. Hallur, Sven Ruf, Manvi Singh, Jörg Czech, Juluri Suresh, Ramachandraiah Gosu, Shama Shaik, Sanjay Venkatachalapathi Kadnur, Swarnakumari Birudukota, Bharat Ravindra Zope, Aimo Kannt, Christine Rudolph
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports
Scientific Reports
Nicotinamide N-methyltransferase (NNMT) is a cytosolic enzyme that catalyzes the transfer of a methyl group from the co-factor S-adenosyl-L-methionine (SAM) onto the substrate, nicotinamide (NA) to form 1-methyl-nicotinamide (MNA). Higher NNMT expres
Autor:
Saravanakumar Dhakshinamoorthy, Dhanalakshmi Sivanandhan, Amir Siddiqui, Zaheerbasha Sameermahmood, Srinivasan Swaminathan, V. Krishnakumar, D.A Jeyaraj, Biswajit Kalita, Rudresh G, Madhuri Kanavalli, Sowmya Ramaiah, Raghunadha Reddy Burri, Sanjay Venkatachalapathi Kadnur, Rajendra Kristam, Sriram Rajagopal, Bharat Ravindra Zope, Sunil Mohire
Publikováno v:
Diabetes. 68
Impaired insulin secretion, a characteristic of type 2 diabetes (T2D) is partly attributed to decreased β-cell mass due to apoptotic cell death under diabetogenic conditions. Current therapies for diabetes do not address apoptotic cell death mediate
Autor:
Saravanakumar Dhakshinamoorthy, Ramachandraiah Gosu, Saravanan Kandan, Herman Schreuder, Suresh Juluri, Raghunadha Reddy Burri, Swarnakumari Birudukota, Aimo Kannt, Christine Rudolph, Shama Shaik, Thomas Langer, Srinivasan Swaminathan, Niranjan Naranapura Anand, Manish Kumar Thakur, Rajendra Kristam, Mahanandeesha S. Hallur, Sridharan Rajagopal, Sven Ruf, Reejuana Parveen
Publikováno v:
Biochemical and biophysical research communications. 491(2)
Nicotinamide N-methyltransferase (NNMT) is a S-adenosyl- l -methionine (SAM)-dependent enzyme that catalyzes N-methylation of nicotinamide (NA) and other pyridines to form N-methyl pyridinium ions. Here we report the first ternary complex X-ray cryst
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112983 (2014)
PLoS ONE
PLoS ONE
The viral protein U (Vpu) encoded by HIV-1 has been shown to assist in the detachment of virion particles from infected cells. Vpu forms cation-specific ion channels in host cells, and has been proposed as a potential drug target. An understanding of
Autor:
Akio Kitao, Takeshi Ishikawa, Nobuyuki Matubayasi, Shun Sakuraba, Kazuo Kuwata, Raghunadha Reddy Burri, Yuji O. Kamatari
Publikováno v:
Physical chemistry chemical physics : PCCP. 15(10)
To examine the stabilities and binding characteristics, fragment molecular orbital (FMO) calculations were performed for the two binding modes of hen egg-white lysozyme with tri-N-acetyl-D-glucosamine (tri-NAG). Solvent effects were considered using
Autor:
Raghunadha Reddy Burri, Nikolai N. Medvedev, Alfons Geiger, Maximilian N. Andrews, Vladimir P. Voloshin, Roland Winter
Publikováno v:
The journal of physical chemistry. B. 115(48)
The study of hydration, folding, and interaction of proteins by volumetric measurements has been promoted by recent advances in the development of highly sensitive instrumentations. However, the separation of the measured apparent volumes into contri
Autor:
Akio Kitao, Raghunadha Reddy Burri
Publikováno v:
Seibutsu Butsuri. 51:S130