CryoBench: Diverse and challenging datasets for the heterogeneity problem in cryo-EM

Autor: Jeon, Minkyu, Raghu, Rishwanth, Astore, Miro, Woollard, Geoffrey, Feathers, Ryan, Kaz, Alkin, Hanson, Sonya M., Cossio, Pilar, Zhong, Ellen D.

Cryo-electron microscopy (cryo-EM) is a powerful technique for determining high-resolution 3D biomolecular structures from imaging data. As this technique can capture dynamic biomolecular complexes, 3D reconstruction methods are increasingly being de

Externí odkaz: http://arxiv.org/abs/2408.05526

Conformational states of the microtubule nucleator, the γ-tubulin ring complex.

Autor: Romer B; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Travis SM; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Mahon BP; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.; Present address: Molecular Structure and Design, Bristol Myers Squibb, Princeton, NJ, USA., McManus CT; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Jeffrey PD; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Coudray N; Department of Cell Biology, NYU School of Medicine, New York City, NY, USA.; Applied Bioinformatics Laboratories, NYU School of Medicine, New York, NY, USA., Raghu R; Department of Computer Science, Princeton University, Princeton, NJ, USA., Rale MJ; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.; Present address: Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Zhong ED; Department of Computer Science, Princeton University, Princeton, NJ, USA., Bhabha G; Department of Cell Biology, NYU School of Medicine, New York City, NY, USA., Petry S; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Dec 21. Date of Electronic Publication: 2023 Dec 21.