Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Raghida Bukhalid"'
Autor:
Naniye Malli Cetinbas, Travis Monnell, Jahna Soomer-James, Pamela Shaw, Kelly Lancaster, Kalli C. Catcott, Melissa Dolan, Rebecca Mosher, Caitlin Routhier, Chen-Ni Chin, Dorin Toader, Jeremy Duvall, Raghida Bukhalid, Timothy B. Lowinger, Marc Damelin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Activating interferon responses with STING agonists (STINGa) is a current cancer immunotherapy strategy, and therapeutic modalities that enable tumor-targeted delivery via systemic administration could be beneficial. Here we demonstrate that
Externí odkaz:
https://doaj.org/article/699282d864e84cab83d32547f5f5c8e1
Autor:
Pamela Shaw, Phonphimon Wongthida, Kalli Catcott, Keith Bentley, Eugene Kelleher, Joshua Thomas, Rebecca Mosher, Dorin Toader, Jeremy Duvall, Raghida Bukhalid, Marc Damelin, Timothy Lowinger, Kelly Lancaster, Anouk Dirksen, Bingfan Du, Timothy Eitas, Naniye Malli, Marina Protopopova, Cheri Stevenson, Alex Uttard
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/6092ea6269d840da93e0822a70aedaac
Autor:
Brian Jones, Pamela Shaw, Naniye Malli Cetinbas, Travis Monnell, Winnie Lee, Kalli Catcott, Chen-Ni Chin, Kelly Slocum, LiuLiang Qin, Kenneth Avocetien, Keith Bentley, Susan Clardy, Eugene Kelleher, Joshua Thomas, Rebecca Mosher, Dorin Toader, Jeremy Duvall, Raghida Bukhalid, Marc Damelin, Timothy Lowinger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/b5031bee1db5458fb014131f0b1a8d8c
Autor:
Beni B. Wolf, Ulrik B. Nielsen, Jonathan B. Fitzgerald, Anne M. King, Callum M. Sloss, Olga Burenkova, Neeraj Kohli, Shannon L. Werner, Nastaran Gerami-Moayed, Gege Tan, Mark Sevecka, Raghida Bukhalid, Jeffrey D. Kearns
Supplementary Methods, Figures S1-S11, and Table Legends. Supplementary Methods: description of methods used in the Supplementary figures, expanded description of ELISA assays, and description of the computational model of multiple EGFR ligand antago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0589dd9379473a98d20e9845ac6751
https://doi.org/10.1158/1535-7163.22501833.v1
https://doi.org/10.1158/1535-7163.22501833.v1
Autor:
Beni B. Wolf, Ulrik B. Nielsen, Jonathan B. Fitzgerald, Anne M. King, Callum M. Sloss, Olga Burenkova, Neeraj Kohli, Shannon L. Werner, Nastaran Gerami-Moayed, Gege Tan, Mark Sevecka, Raghida Bukhalid, Jeffrey D. Kearns
Supplementary Tables S2, S3, S4. Structure of the computational model of multiple ligand antagonists: species (Table S2), parameters (Table S3), and Reactions (Table S4).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c534d560032452e0b5101eea8d16d10b
https://doi.org/10.1158/1535-7163.22501827
https://doi.org/10.1158/1535-7163.22501827
Autor:
Beni B. Wolf, Ulrik B. Nielsen, Jonathan B. Fitzgerald, Anne M. King, Callum M. Sloss, Olga Burenkova, Neeraj Kohli, Shannon L. Werner, Nastaran Gerami-Moayed, Gege Tan, Mark Sevecka, Raghida Bukhalid, Jeffrey D. Kearns
Supplementary Table S1. Cell lines and cell culture conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0501a563d004db70756494b7092751e4
https://doi.org/10.1158/1535-7163.22501830
https://doi.org/10.1158/1535-7163.22501830
Autor:
Beni B. Wolf, Ulrik B. Nielsen, Jonathan B. Fitzgerald, Anne M. King, Callum M. Sloss, Olga Burenkova, Neeraj Kohli, Shannon L. Werner, Nastaran Gerami-Moayed, Gege Tan, Mark Sevecka, Raghida Bukhalid, Jeffrey D. Kearns
Supplementary Tables S5, S6, S7, S8. mRNA expression data for EGFR ligands as measured by RNAseq from The Cancer Genome Atlas (TCGA) across 14 cancer indications or by RT-qPCR of colorectal cancer FFPE samples. Table S5: Summary of TCGA datasets incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5782fe1fa8c256671852ceadb513a3f4
https://doi.org/10.1158/1535-7163.22501824
https://doi.org/10.1158/1535-7163.22501824
Autor:
Naniye Malli Cetinbas, Kalli C. Catcott, Travis Monnell, Jahna Soomer-James, Keith Bentley, Susan Clardy, Bingfan Du, Eoin Kelleher, Marina Protopopova, Cheri Stevenson, Joshua D. Thomas, Alex Uttard, Dorin Toader, Jeremy Duvall, Raghida Bukhalid, Marc Damelin, Timothy B. Lowinger
Publikováno v:
Cancer Research. 82:2114-2114
STING pathway agonism has emerged as a potential therapeutic strategy to stimulate anti-tumor immune responses. We have previously shown that tumor cell-targeted antibody-drug conjugates (ADCs) carrying a novel STING agonist induce anti-tumor activit
Publikováno v:
Plant disease. 81(8)
Autor:
Neeraj Kohli, Olga Burenkova, Mark Sevecka, Ulrik B. Nielsen, Nastaran Gerami-Moayed, Callum M. Sloss, Raghida Bukhalid, Jonathan Fitzgerald, Beni B. Wolf, Shannon L. Werner, Jeffrey D. Kearns, Gege Tan, Anne M. King
Publikováno v:
Molecular Cancer Therapeutics. 14:1625-1636
Although EGFR is a validated therapeutic target across multiple cancer indications, the often modest clinical responses to current anti-EGFR agents suggest the need for improved therapeutics. Here, we demonstrate that signal amplification driven by h